To die or not to die: how does p53 decide? (Q28255819)

Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane

Europe PubMed Central

title

To die or not to die: how does p53 decide? (English)

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author name string

Elizabeth A Slee

series ordinal

1

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Daniel J O'Connor

series ordinal

2

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Xin Lu

series ordinal

3

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language of work or name

English

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publication date

12 April 2004

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published in

Oncogene

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volume

23

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issue

16

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page(s)

2809-18

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cites work

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Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: correlation with clinical outcome

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Drosophila p53 preserves genomic stability by regulating cell death

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Identification of a novel p53 functional domain that is necessary for efficient growth suppression

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DNA damage-induced inhibition of securin expression is mediated by p53.

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Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

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Chk1 and Chk2 kinases in checkpoint control and cancer

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Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

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The p53 proto-oncogene can act as a suppressor of transformation

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p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

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Pharmacological rescue of mutant p53 conformation and function

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Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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Synergistic activation of transcription by CBP and p53

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Mdm2 promotes the rapid degradation of p53

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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

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Cooper instability of composite fermions

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Regulation of p53 stability by Mdm2

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7 January 2021

T antigen is bound to a host protein in SY40-transformed cells

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Data mining the p53 pathway in the Fugu genome: evidence for strong conservation of the apoptotic pathway

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Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

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The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis

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p53 is required for radiation-induced apoptosis in mouse thymocytes

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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Stress signals induce transcriptionally inactive E2F-1 independently of p53 and Rb

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p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

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Amplification of a gene encoding a p53-associated protein in human sarcomas

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7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

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Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.

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7 January 2021

A model for p53-induced apoptosis

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7 January 2021

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Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions.

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7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

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7 January 2021

Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207516

7 January 2021

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207516

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207516

7 January 2021

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207516

7 January 2021

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207516

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207516

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

4752786

1040807258

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4752786

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference