The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity (Q28260075)

positive regulation of toll-like receptor 7 signaling pathway

1 reference

Myeloid differentiation primary response gene 88

1 reference

Toll-like receptor 7

1 reference

Triggering receptor expressed on myeloid cells-like 4

1 reference

10

Nir Hacohen

0 references

David E Root

6

object named as

David E Root

0 references

Glenn S Cowley

5

object named as

Glenn S Cowley

0 references

author name string

Zaida G Ramirez-Ortiz

1

0 references

Amit Prasad

2

0 references

Jason W Griffith

3

0 references

William F Pendergraft

4

0 references

Melissa Tai

7

0 references

Andrew D Luster

8

0 references

Joseph El Khoury

9

0 references

Terry K Means

describes a project that uses

11

0 references

language of work or name

English

0 references

publication date

May 2015

0 references

published in

Nature Immunology

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volume

16

0 references

issue

5

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page(s)

495-504

0 references

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4406861/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

TLRs and interferons: a central paradigm in autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

TREM2 Variants in Alzheimer's Disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells

20 March 2017

1 reference

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Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

20 March 2017

1 reference

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Toll-like receptor signalling

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

20 March 2017

1 reference

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Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

20 March 2017

1 reference

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TREM-1 amplifies inflammation and is a crucial mediator of septic shock

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

20 March 2017

1 reference

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TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

7 April 2017

1 reference

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Integrative DNA, RNA, and protein evidence connects TREML4 to coronary artery calcification

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Genetic variations in Toll-like receptors (TLRs 3/7/8) are associated with systemic lupus erythematosus in a Taiwanese population

29 September 2017

1 reference

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The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity

29 September 2017

1 reference

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Structure, expression pattern and biological activity of molecular complex TREM-2/DAP12.

29 September 2017

1 reference

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Nucleic acid recognition by the innate immune system

29 September 2017

1 reference

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TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus

29 September 2017

1 reference

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TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Cross-regulation of signaling by ITAM-associated receptors

29 September 2017

1 reference

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TREM and TREM-like receptors in inflammation and disease

29 September 2017

1 reference

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TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Highly parallel identification of essential genes in cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Functional genomics of silencing TREM-1 on TLR4 signaling in macrophages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

The TREM receptor family and signal integration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

A Tlr7 translocation accelerates systemic autoimmunity in murine lupus

29 September 2017

1 reference

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Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

STAT1 plays a role in TLR signal transduction and inflammatory responses.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

T cell-independent and toll-like receptor-dependent antigen-driven activation of autoreactive B cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

Drosophila Toll and IL-1 receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406861

The history of Toll-like receptors - redefining innate immunity.

2 June 2018

1 reference

Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12.

21 January 2018

1 reference

Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.

21 January 2018

1 reference

Novel genes detected by transcriptional profiling from whole-blood cells in patients with early onset of acute coronary syndrome.

21 January 2018

1 reference

Cutting Edge: TREM-2 Attenuates Macrophage Activation

21 January 2018

1 reference

Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25848864

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.3143

1 reference

1 reference

1 reference

PubMed publication ID

25848864

1 reference