Central role for PELP1 in nonandrogenic activation of the androgen receptor in prostate cancer (Q28261485)

2

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Meera Ramanan

3

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Payal Kapur

4

0 references

Stephen R Hammes

5

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Jer-Tsong Hsieh

6

0 references

Ganesh V Raj

Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis

7

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language of work or name

English

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publication date

April 2012

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published in

Molecular Endocrinology

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volume

26

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issue

4

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page(s)

550-61

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cites work

1 reference

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PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity

26 May 2017

1 reference

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PELP1: A novel therapeutic target for hormonal cancers

26 May 2017

1 reference

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The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype

26 May 2017

1 reference

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PELP1--a novel estrogen receptor-interacting protein

26 May 2017

1 reference

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Endocrine disruptors and prostate cancer risk

26 May 2017

1 reference

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Functional and biological properties of the nuclear receptor coregulator PELP1/MNAR

26 May 2017

1 reference

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Proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor enhances androgen receptor functions through LIM-only coactivator, four-and-a-half LIM-only protein 2

26 May 2017

1 reference

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The transcriptional corepressor, PELP1, recruits HDAC2 and masks histones using two separate domains

26 May 2017

1 reference

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Molecular determinants of resistance to antiandrogen therapy

26 May 2017

1 reference

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Molecular cloning and characterization of PELP1, a novel human coregulator of estrogen receptor alpha

26 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Elevated androgens and prolactin in aromatase-deficient mice cause enlargement, but not malignancy, of the prostate gland

26 May 2017

1 reference

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Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated

26 May 2017

1 reference

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Starving the addiction: new opportunities for durable suppression of AR signaling in prostate cancer

29 September 2017

1 reference

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Microarray coupled to quantitative RT-PCR analysis of androgen-regulated genes in human LNCaP prostate cancer cells

29 September 2017

1 reference

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Androgen modulation of coregulator expression in prostate cancer cells.

29 September 2017

1 reference

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Targeting the androgen receptor pathway in prostate cancer

29 September 2017

1 reference

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Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer

29 September 2017

1 reference

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Molecular signaling pathways that regulate prostate gland development

29 September 2017

1 reference

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A potential paradox in prostate adenocarcinoma progression: oestrogen as the initiating driver

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

MNAR plays an important role in ERa activation of Src/MAPK and PI3K/Akt signaling pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

The role of estrogens and estrogen receptors in normal prostate growth and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Estrogen action on the prostate gland: a critical mix of endocrine and paracrine signaling.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Estrogens and mechanisms of prostate cancer progression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

17beta-Estradiol differentially regulates androgen-responsive genes through estrogen receptor-beta- and extracellular-signal regulated kinase-dependent pathways in LNCaP human prostate cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Emerging significance of ER-coregulator PELP1/MNAR in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Estrogen signaling and disruption of androgen metabolism in acquired androgen-independence during cadmium carcinogenesis in human prostate epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Estrogen receptor beta (ERbeta) and inhibition of prostate cancer cell proliferation: studies on the possible mechanism of action in DU145 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Aromatase and prostate cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 2: Androgen-receptor cofactors and bypass pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: Modifications to the androgen receptor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

The modulator of nongenomic actions of the estrogen receptor (MNAR) regulates transcription-independent androgen receptor-mediated signaling: evidence that MNAR participates in G protein-regulated meiosis in Xenopus laevis oocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Role of estrogens in development of prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Epigenetic changes in prostate cancer: implication for diagnosis and treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Estrogen receptor beta in prostate cancer: brake pedal or accelerator?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Frequent methylation of estrogen receptor in prostate cancer: correlation with tumor progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Role of PELP1/MNAR signaling in ovarian tumorigenesis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Estrogen enhancement of androgen-responsive gene expression in hormone-induced hyperplasia in the ventral prostate of F344 rats

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Progesterone receptor expression in human prostate cancer: correlation with tumor progression

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Frequent loss of estrogen receptor-beta expression in prostate cancer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417135

Expression of estrogen receptor (ER-alpha and ER-beta) mRNA in human prostate cancer

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22403175

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Metastases of prostate cancer express estrogen receptor-beta

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22403175

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Loss of estrogen receptor beta expression in malignant human prostate cells in primary cultures and in prostate cancer tissues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22403175