Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model. (Q28261563)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405502%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model (English)

1 reference

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25 January 2020

1 reference

5

1 reference

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25 January 2020

author name string

S M Goebel-Goody

1

1 reference

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25 January 2020

E D Wilson-Wallis

2

1 reference

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25 January 2020

S Royston

3

1 reference

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25 January 2020

S M Tagliatela

4

1 reference

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25 January 2020

P J Lombroso

6

1 reference

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25 January 2020

language of work or name

English

0 references

publication date

6 April 2012

1 reference

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Genes, Brain and Behavior

25 January 2020

published in

1 reference

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25 January 2020

volume

11

1 reference

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25 January 2020

issue

5

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25 January 2020

page(s)

586-600

1 reference

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describes a project that uses

25 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3922131/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Differential interaction of the tyrosine phosphatases PTP-SL, STEP and HePTP with the mitogen-activated protein kinases ERK1/2 and p38alpha is determined by a kinase specificity sequence and influenced by reducing agents

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Evidence that fragile X mental retardation protein is a negative regulator of translation

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STEP61: a member of a family of brain-enriched PTPs is localized to the endoplasmic reticulum

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The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

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Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD

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NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling

20 March 2017

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Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase

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Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice

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Altered neocortical rhythmic activity states in Fmr1 KO mice are due to enhanced mGluR5 signaling and involve changes in excitatory circuitry

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Imbalance of neocortical excitation and inhibition and altered UP states reflect network hyperexcitability in the mouse model of fragile X syndrome

29 September 2017

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29 September 2017

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Unaltered hormonal response to stress in a mouse model of fragile X syndrome

29 September 2017

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Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome

29 September 2017

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29 September 2017

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FMRP mediates mGluR5-dependent translation of amyloid precursor protein

29 September 2017

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29 September 2017

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29 September 2017

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The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95

29 September 2017

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Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation

29 September 2017

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Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420.

29 September 2017

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Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation

29 September 2017

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Developmental and genetic audiogenic seizure models: behavior and biological substrates

29 September 2017

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29 September 2017

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Molecular and cellular genetics of fragile X syndrome

29 September 2017

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Hairpins are formed by the single DNA strands of the fragile X triplet repeats: structure and biological implications

29 September 2017

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Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines

29 September 2017

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Ethologically-based animal models of anxiety disorders

29 September 2017

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Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome

29 September 2017

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Autism profiles of males with fragile X syndrome

2 June 2018

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Immunocytochemical localization of the striatal enriched protein tyrosine phosphatase in the rat striatum: a light and electron microscopic study with a complementary DNA-generated polyclonal antibody

2 June 2018

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Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety.

2 June 2018

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Mapping patterns of c-fos expression in the central nervous system after seizure

2 June 2018

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Biochemical characterization of a filtered synaptoneurosome preparation from guinea pig cerebral cortex: cyclic adenosine 3':5'-monophosphate-generating systems, receptors, and enzymes

2 June 2018

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The greeting behavior of fragile X males.

2 June 2018

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Audiogenic seizures evoked in DBA/2 mice induce c-fos oncogene expression into subcortical auditory nuclei.

2 June 2018

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Evaluation of marble-burying behavior as a model of anxiety.

2 June 2018

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Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice

2 June 2018

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Prolonged epileptiform discharges induced by altered group I metabotropic glutamate receptor-mediated synaptic responses in hippocampal slices of a fragile X mouse model.

21 January 2018

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Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

21 January 2018

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Neurons in the deep layers of superior colliculus play a critical role in the neuronal network for audiogenic seizures: mechanisms for production of wild running behavior

21 January 2018

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Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices

21 January 2018

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Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome

21 January 2018

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Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome

21 January 2018

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Audiogenic seizures susceptibility in transgenic mice with fragile X syndrome.

21 January 2018

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The periaqueductal grey is a critical site in the neuronal network for audiogenic seizures: modulation by GABA(A), NMDA and opioid receptors

21 January 2018

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(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features

21 January 2018

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Genetic-background modulation of core and variable autistic-like symptoms in Fmr1 knock-out mice

21 January 2018

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Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.

21 January 2018

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Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model

21 January 2018

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Tyrosine phosphatases regulate AMPA receptor trafficking during metabotropic glutamate receptor-mediated long-term depression.

27 November 2018

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Effects of harmaline on anxiety-related behavior in mice

27 November 2018

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Ethopharmacological analysis of rat behavior on the elevated plus-maze.

27 November 2018

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Social Dominance in Inbred Mouse Strains

27 November 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1601-183X.2012.00781.X

10.1111/J.1601-183X.2012.00781.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405502%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

25 January 2020

2348665

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22405502%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

22405502

1 reference