HIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidase (Q28261913)

2

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O Chaloin

3

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R El-Khoury

4

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M Brabant

5

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A Langonné

6

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M Porceddu

7

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J-J Brière

8

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N Buron

9

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D Rebouillat

10

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C Péchoux

11

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A Deniaud

12

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C Brenner

13

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J-P Briand

14

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S Muller

15

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P Rustin

16

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E Jacotot

Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization

17

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language of work or name

English

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publication date

15 March 2012

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published in

Cell Death and Disease

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volume

3

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issue

3

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page(s)

e282

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cites work

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Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

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HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.

20 March 2017

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Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation

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Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2

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The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore

20 March 2017

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Energy transduction in ATP synthase

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7 April 2017

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The HIV-1 transactivator factor (Tat) induces enterocyte apoptosis through a redox-mediated mechanism

7 April 2017

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Developing neuroprotective strategies for treatment of HIV-associated neurocognitive dysfunction

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A flavivirus protein M-derived peptide directly permeabilizes mitochondrial membranes, triggers cell death and reduces human tumor growth in nude mice

29 September 2017

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Role of Tat protein in HIV neuropathogenesis

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Mitochondrial outer-membrane permeabilization and remodelling in apoptosis

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HIV Protease Cleavage of Procaspase 8 is Necessary for Death of HIV-Infected Cells

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The HIV-1 Tat protein: a multifaceted target for novel therapeutic opportunities

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Viral proteins targeting mitochondria: controlling cell death

29 September 2017

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Respiratory chain defects: what do we know for sure about their consequences in vivo?

29 September 2017

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HIV infection, highly active antiretroviral therapy and the cardiovascular system

29 September 2017

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Pathogenesis of Human Immunodeficiency Virus-Induced Neurological Disease

29 September 2017

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Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

29 September 2017

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Mitochondrial cytochrome c oxidase as a target site for cephalosporin antibiotics in renal epithelial cells (LLC-PK(1)) and renal cortex

29 September 2017

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Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins Tat and gp120.

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Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope

29 September 2017

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Identification of bovine heart cytochrome c oxidase subunits modified by the lipid peroxidation product 4-hydroxy-2-nonenal

29 September 2017

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Nitric oxide and cytochrome oxidase: substrate, inhibitor or effector?

29 September 2017

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The rotary machine in the cell, ATP synthase

29 September 2017

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Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.

29 September 2017

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From the outside in: extracellular activities of HIV Tat.

29 September 2017

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Susceptibility of HIV-1-TAT transfected cells to undergo apoptosis. Biochemical mechanisms

29 September 2017

1 reference

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The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins

29 September 2017

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Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2

29 September 2017

1 reference

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Tat protein of human immunodeficiency virus type 1 represses expression of manganese superoxide dismutase in HeLa cells

29 September 2017

1 reference

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Full peptide synthesis, purification, and characterization of six Tat variants. Differences observed between HIV-1 isolates from Africa and other continents

29 September 2017

1 reference

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Tat acetylation regulates its actions on microtubule dynamics and apoptosis in T lymphocytes

2 June 2018

1 reference

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HIV-1 trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons.

21 January 2018

1 reference

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Targeted myocardial transgenic expression of HIV Tat causes cardiomyopathy and mitochondrial damage.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDDIS.2012.21

The N-terminus of HIV-1 Tat protein is essential for Tat-TAR RNA interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2012.21

Real-time flow cytometry analysis of permeability transition in isolated mitochondria

21 January 2018

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Caspase-independent cell death by low concentrations of nitric oxide in PC12 cells: involvement of cytochrome C oxidase inhibition and the production of reactive oxygen species in mitochondria

21 January 2018

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Inhibition of cytochrome c oxidase activity in rat cerebral cortex and human skeletal muscle by D-2-hydroxyglutaric acid in vitro.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDDIS.2012.21

The tumor suppressor protein PML controls apoptosis induced by the HIV-1 envelope.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDDIS.2012.21

Isolation of mitochondria from rat brain using Percoll density gradient centrifugation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2012.21

HIV Type 1 Tat Protein Is a Survival Factor for Kaposi's Sarcoma and Endothelial Cells

21 January 2018

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Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases

21 January 2018

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12 December 2020

The binding affinity of double-stranded RNA motifs to HIV-1 Tat protein affects transactivation and the neutralizing capacity of anti-Tat antibodies elicited after intranasal immunization

1 reference

12 December 2020

Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis

1 reference

12 December 2020

Development of a fully automated multichannel peptide synthesizer with integrated TFA cleavage capability

1 reference

12 December 2020

Biochemical and molecular investigations in respiratory chain deficiencies

1 reference

12 December 2020

A synthetic HIV-1 Tat protein breaches the skin barrier and elicits Tat-neutralizing antibodies and cellular immunity

1 reference

12 December 2020