Penicillin-binding proteins and beta-lactam resistance (Q28267300)

FEMS Microbiology Reviews

Europe PubMed Central

title

Penicillin-binding proteins and beta-lactam resistance (English)

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André Zapun

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author name string

André Zapun

series ordinal

1

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Carlos Contreras-Martel

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2

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Thierry Vernet

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3

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language of work or name

English

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publication date

March 2008

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published in

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volume

32

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page(s)

361-85

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issue

2

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cites work

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Interaction energies between beta-lactam antibiotics and E. coli penicillin-binding protein 5 by reversible thermal denaturation

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Permeability and penicillin-binding protein alterations in Salmonella muenchen: stepwise resistance acquired during beta-lactam therapy

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Novel resistance to imipenem associated with an altered PBP-4 in a Pseudomonas aeruginosa clinical isolate.

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Interspecies recombination between the penA genes of Neisseria meningitidis and commensal Neisseria species during the emergence of penicillin resistance in N. meningitidis: natural events and laboratory simulation

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Insertion of an extra amino acid is the main cause of the low affinity of penicillin-binding protein 2 in penicillin-resistant strains of Neisseria gonorrhoeae.

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The prevalence of methicillin-resistant staphylococci in healthy horses in the Netherlands

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Pneumococcal beta-lactam resistance due to a conformational change in penicillin-binding protein 2x.

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Kinetics of penicillin binding to penicillin-binding proteins of Staphylococcus aureus

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Increase of the deacylation rate of PBP2x from Streptococcus pneumoniae by single point mutations mimicking the class A beta-lactamases.

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The structural modifications induced by the M339F substitution in PBP2x from Streptococcus pneumoniae further decreases the susceptibility to beta-lactams of resistant strains

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Identical penicillin-binding domains in penicillin-binding proteins of Streptococcus pneumoniae clinical isolates with different levels of beta-lactam resistance

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Molecular basis of the non-beta-lactamase-mediated resistance to beta-lactam antibiotics in strains of Haemophilus influenzae isolated in Canada

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Horizontal transfer of multiple penicillin-binding protein genes, and capsular biosynthetic genes, in natural populations of Streptococcus pneumoniae.

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Genetic analysis of clinical isolates of Streptococcus pneumoniae with high-level resistance to expanded-spectrum cephalosporins

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Serotype 14 variants of the Spanish penicillin-resistant serotype 9V clone of Streptococcus pneumoniae arose by large recombinational replacements of the cpsA-pbp1a region.

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Development of methicillin resistance in clinical isolates of Staphylococcus sciuri by transcriptional activation of the mecA homologue native to s.

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Diversity of beta-lactam resistance-conferring amino acid substitutions in penicillin-binding protein 3 of Haemophilus influenzae.

21 January 2018

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Activities of ceftobiprole and other beta-lactams against Streptococcus pneumoniae clinical isolates from the United States with defined substitutions in penicillin-binding proteins PBP 1a, PBP 2b, and PBP 2x.

21 January 2018

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Antibiotic resistance as a stress response: complete sequencing of a large number of chromosomal loci in Staphylococcus aureus strain COL that impact on the expression of resistance to methicillin

21 January 2018

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Characterization of an In vitro-selected amoxicillin-resistant strain of Helicobacter pylori

21 January 2018

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Fast lysis of Escherichia coli filament cells requires differentiation of potential division sites

21 January 2018

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Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations

21 January 2018

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Genetic analysis and penicillin-binding protein alterations in Neisseria gonorrhoeae with chromosomally mediated resistance

21 January 2018

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Penicillin-binding proteins of penicillin-susceptible and intrinsically resistant Neisseria gonorrhoeae.

21 January 2018

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Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae

21 January 2018

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Extensive re-modelling of the transpeptidase domain of penicillin-binding protein 2B of a penicillin-resistant South African isolate of Streptococcus pneumoniae

21 January 2018

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Penicillin-resistant viridans streptococci have obtained altered penicillin-binding protein genes from penicillin-resistant strains of Streptococcus pneumoniae

21 January 2018

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The penicillin resistance of Enterococcus faecalis JH2-2r results from an overproduction of the low-affinity penicillin-binding protein PBP4 and does not involve a psr-like gene

21 January 2018

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Analysis of penicillin-binding protein lb and 2a genes from Streptococcus pneumoniae

21 January 2018

1 reference

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Analysis of penicillin-binding protein genes of clinical isolates of Streptococcus pneumoniae with reduced susceptibility to amoxicillin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Fitness cost of SCCmec and methicillin resistance levels in Staphylococcus aureus

21 January 2018

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Extensive variation in the ddl gene of penicillin-resistant Streptococcus pneumoniae results from a hitchhiking effect driven by the penicillin-binding protein 2b gene.

21 January 2018

1 reference

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Alterations to penicillin-binding proteins 1A, 2B and 2X amongst penicillin-resistant clinical isolates of Streptococcus pneumoniae serotype 23F from the nasopharyngeal flora of children.

21 January 2018

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Inhibition of the expression of penicillin resistance in Streptococcus pneumoniae by inactivation of cell wall muropeptide branching genes.

21 January 2018

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Transition from resistance to hypersusceptibility to beta-lactam antibiotics associated with loss of a low-affinity penicillin-binding protein in a Streptococcus faecium mutant highly resistant to penicillin

21 January 2018

1 reference

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Overproduction of a low-affinity penicillin-binding protein and high-level ampicillin resistance in Enterococcus faecium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

The basis for resistance to beta-lactam antibiotics by penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Activation for catalysis of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus by bacterial cell wall

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Mechanistic basis for the action of new cephalosporin antibiotics effective against methicillin- and vancomycin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Alterations in peptidoglycan of Neisseria gonorrhoeae induced by sub-MICs of beta-lactam antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

A biological price of antibiotic resistance: major changes in the peptidoglycan structure of penicillin-resistant pneumococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Imipenem resistance in Acinetobacter baumanii is due to altered penicillin-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-binding proteins in a Staphylococcus aureus strain resistant to specific beta-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Alterations in penicillin-binding protein 1A confer resistance to beta-lactam antibiotics in Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

The crystal structure of the penicillin-binding protein 2x from Streptococcus pneumoniae and its acyl-enzyme form: implication in drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Resistance of Pseudomonas aeruginosa to cefsulodin: modification of penicillin-binding protein 3 and mapping of its chromosomal gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Reaction of soluble penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus with beta-lactams and acyclic substrates: kinetics in homogeneous solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Participation of PBP 3 in the acquisition of dicloxacillin resistance in Listeria monocytogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Point mutations in Staphylococcus aureus PBP 2 gene affect penicillin-binding kinetics and are associated with resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Multiple changes of penicillin-binding proteins in penicillin-resistant clinical isolates of Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Interaction of non-lytic beta-lactams with penicillin-binding proteins in Streptococcus pneumoniae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Rapidly increasing prevalence of beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae type b in patients with meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

In vitro and in vivo properties of Ro 63-9141, a novel broad-spectrum cephalosporin with activity against methicillin-resistant staphylococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Amino acid substitutions that reduce the affinity of penicillin-binding protein 3 of Escherichia coli for cephalexin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Influence of femB on methicillin resistance and peptidoglycan metabolism in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

The emergence and evolution of methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Structure-activity relationships of different beta-lactam antibiotics against a soluble form of Enterococcus faecium PBP5, a type II bacterial transpeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in Central Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-binding protein 2x of Streptococcus pneumoniae: enzymic activities and interactions with beta-lactams

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Role of penicillin-binding protein 5 C-terminal amino acid substitutions in conferring ampicillin resistance in Norwegian clinical strains of Enterococcus faecium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Genetic and molecular characterization of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae with unusually high resistance to ampicillin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Overproduction of a penicillin-binding protein is not the only mechanism of penicillin resistance in Enterococcus faecium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Alterations of penicillin-binding proteins 1A, 2X, and 2B in Streptococcus pneumoniae isolates for which amoxicillin MICs are higher than penicillin MICs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

High-level beta-lactam resistance associated with acquired multidrug resistance in Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-binding proteins in beta-lactam-resistant laboratory mutants of Streptococcus pneumoniae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Interspecies recombinational events during the evolution of altered PBP 2x genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Role of penicillin-binding protein 2 (PBP2) in the antibiotic susceptibility and cell wall cross-linking of Staphylococcus aureus: evidence for the cooperative functioning of PBP2, PBP4, and PBP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Bacteriostatic and bactericidal activities of beta-lactams against Streptococcus (Enterococcus) faecium are associated with saturation of different penicillin-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus: kinetic characterization of its interactions with beta-lactams using electrospray mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Kinetics of beta-lactam interactions with penicillin-susceptible and -resistant penicillin-binding protein 2x proteins from Streptococcus pneumoniae. Involvement of acylation and deacylation in beta-lactam resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-resistant isolates of Neisseria lactamica produce altered forms of penicillin-binding protein 2 that arose by interspecies horizontal gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Cloning and expression of genes responsible for altered penicillin-binding proteins 3a and 3b in Haemophilus influenzae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Isolation of an ampicillin-resistant, non-beta-lactamase-producing strain of Haemophilus influenzae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

The CiaRH system of Streptococcus pneumoniae prevents lysis during stress induced by treatment with cell wall inhibitors and by mutations in pbp2x involved in beta-lactam resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Contribution of beta-lactamase and PBP amino acid substitutions to amoxicillin/clavulanate resistance in beta-lactamase-positive, amoxicillin/clavulanate-resistant Haemophilus influenzae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Identification of multiple clones of extended-spectrum cephalosporin-resistant Streptococcus pneumoniae isolates in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Characterization of non-beta-lactamase-mediated ampicillin resistance in Haemophilus influenzae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Relative penicillin G resistance in Neisseria meningitidis and reduced affinity of penicillin-binding protein 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Species-Specific Resistance to Antimicrobial Synergism in Streptococcus faecium and Streptococcus faecalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Identification of a structural determinant for resistance to beta-lactam antibiotics in Gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Mutations in the active site of penicillin-binding protein PBP2x from Streptococcus pneumoniae. Role in the specificity for beta-lactam antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Beta-lactamase-producing enterococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Effects of amino acid alterations in penicillin-binding proteins (PBPs) 1a, 2b, and 2x on PBP affinities of penicillin, ampicillin, amoxicillin, cefditoren, cefuroxime, cefprozil, and cefaclor in 18 clinical isolates of penicillin-susceptible, -inte

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Imipenem resistance in clinical isolates of Proteus mirabilis associated with alterations in penicillin-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-binding protein 1A, 2B, and 2X alterations in Canadian isolates of penicillin-resistant Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-binding proteins of Rhodococcus equi: potential role in resistance to imipenem

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

A change in PBP1 is involved in amoxicillin resistance of clinical isolates of Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Understanding the acylation mechanisms of active-site serine penicillin-recognizing proteins: a molecular dynamics simulation study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Mechanisms of resistance to imipenem and ampicillin in Enterococcus faecalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Genetic approach to study the relationship between penicillin-binding protein 3 mutations and Haemophilus influenzae beta-lactam resistance by using site-directed mutagenesis and gene recombinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Molecular characteristics of penicillin-binding protein genes of penicillin-nonsusceptible Streptococcus pneumoniae isolated in the Netherlands

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Anti-MRSA beta-lactams in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Biochemical characterization of Streptococcus pneumoniae penicillin-binding protein 2b and its implication in beta-lactam resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Molecular analysis of a beta-lactam resistance gene encoded within the cephamycin gene cluster of Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Mechanism of resistance of an ampicillin-resistant, beta-lactamase-negative clinical isolate of Haemophilus influenzae type b to beta-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Mutations of the Helicobacter pylori genes rdxA and pbp1 cause resistance against metronidazole and amoxicillin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Role of PBP1 in cell division of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

A comparison of the in-vitro activity of seventeen antibiotics against Streptococcus faecalis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Alteration of PBP 3 entails resistance to imipenem in Listeria monocytogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Presence of an additional penicillin-binding protein in methicillin-resistant Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, and Staphylococcus simulans with a low affinity for methicillin, cephalothin, and cefamand

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

An acquired and a native penicillin-binding protein cooperate in building the cell wall of drug-resistant staphylococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Complementation of the essential peptidoglycan transpeptidase function of penicillin-binding protein 2 (PBP2) by the drug resistance protein PBP2A in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Direct quantitation of the numbers of individual penicillin-binding proteins per cell in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Inhibition of beta-lactam antibiotics at two different times in the cell cycle of Streptococcus faecium ATCC 9790

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-binding proteins as resistance determinants in clinical isolates of Streptococcus pneumoniae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

A global gene pool for high-level cephalosporin resistance in commensal Streptococcus species and Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-binding protein 5 and expression of ampicillin resistance in Enterococcus faecium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Impact of specific pbp5 mutations on expression of beta-lactam resistance in Enterococcus faecium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-binding protein 5 sequence alterations in clinical isolates of Enterococcus faecium with different levels of beta-lactam resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Neisseria lactamica and Neisseria polysaccharea as possible sources of meningococcal beta-lactam resistance by genetic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Complete sequences of six penicillin-binding protein genes from 40 Streptococcus pneumoniae clinical isolates collected in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

The 2.4-A crystal structure of the penicillin-resistant penicillin-binding protein PBP5fm from Enterococcus faecium in complex with benzylpenicillin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Presence of new mecA and mph(C) variants conferring antibiotic resistance in Staphylococcus spp. isolated from the skin of horses before and after clinic admission

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Unusual septum formation in Streptococcus pneumoniae mutants with an alteration in the D,D-carboxypeptidase penicillin-binding protein 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Separation of abnormal cell wall composition from penicillin resistance through genetic transformation of Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Mosaic pbpX genes of major clones of penicillin-resistant Streptococcus pneumoniae have evolved from pbpX genes of a penicillin-sensitive Streptococcus oralis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Role of penicillin-binding protein 5 in expression of ampicillin resistance and peptidoglycan structure in Enterococcus faecium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Alterations in penicillin-binding protein 2B from penicillin-resistant wild-type strains of Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Alterations in MurM, a cell wall muropeptide branching enzyme, increase high-level penicillin and cephalosporin resistance in Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Site-specific mutagenesis analysis of PBP 1A from a penicillin-cephalosporin-resistant pneumococcal isolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Amino acid mutations essential to production of an altered PBP 2X conferring high-level beta-lactam resistance in a clinical isolate of Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Altered PBP 2A and its role in the development of penicillin, cefotaxime, and ceftriaxone resistance in a clinical isolate of Streptococcus pneumoniae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Escherichia coli resistance to β-lactam antibiotics through a decrease in the affinity of a target for lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Hybrid penicillin-binding proteins in penicillin-resistant strains of Neisseria gonorrhoeae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Recruitment of a penicillin-binding protein gene from Neisseria flavescens during the emergence of penicillin resistance in Neisseria meningitidis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Role of interspecies transfer of chromosomal genes in the evolution of penicillin resistance in pathogenic and commensal Neisseria species

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Cell wall monoglycine cross-bridges and methicillin hypersusceptibility in a femAB null mutant of methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Kinetic and mechanistic studies of penicillin-binding protein 2x from Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

New mechanism for methicillin resistance in Staphylococcus aureus: clinical isolates that lack the PBP 2a gene and contain normal penicillin-binding proteins with modified penicillin-binding capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Antimicrobial resistance in Haemophilus influenzae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Association of amino acid substitutions in penicillin-binding protein 3 with beta-lactam resistance in beta-lactamase-negative ampicillin-resistant Haemophilus influenzae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Antibiotic susceptibility in relation to penicillin-binding protein genes and serotype distribution of Streptococcus pneumoniae strains responsible for meningitis in Japan, 1999 to 2002.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Role of an altered penicillin-binding protein in methicillin- and cephem-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

The fib locus in Streptococcus pneumoniae is required for peptidoglycan crosslinking and PBP-mediated beta-lactam resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Alterations to the penicillin-binding proteins in the Bacteroides fragilis group: a mechanism for non-beta-lactamase mediated cefoxitin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Methicillin-resistant coagulase-negative staphylococci isolated from healthy horses in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Interactions between penicillin-binding proteins (PBPs) and two novel classes of PBP inhibitors, arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-ones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

A proteolytic transmembrane signaling pathway and resistance to beta-lactams in staphylococci

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Identification and characterization of the penicillin-binding protein 2a of Streptococcus pneumoniae and its possible role in resistance to beta-lactam antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Penicillin-binding proteins of multiply antibiotic-resistant South African strains of Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faecium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Resistance to β-lactam antibiotics by re-modelling the active site of an E. coli penicillin-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Genetics of high level penicillin resistance in clinical isolates ofStreptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X

Genetics of resistance to third-generation cephalosporins in clinical isolates of Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1574-6976.2007.00095.X