E2F1 in melanoma progression and metastasis (Q28268420)

1

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David Engelmann

2

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Annett Niemetz

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Jens Pahnke

4

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Anke Schmidt

5

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Manfred Kunz

6

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Stephan Emmrich

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Marc Steder

8

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Dirk Koczan

9

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Brigitte M Pützer

Journal of the National Cancer Institute

10

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language of work or name

English

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publication date

20 January 2010

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published in

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volume

102

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issue

2

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page(s)

127-33

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cites work

Rb function in cell-cycle regulation and apoptosis

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E2F-1 induces proliferation-specific genes and suppresses squamous differentiation-specific genes in human epidermal keratinocytes

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Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation

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Multiple members of the E2F transcription factor family are the products of oncogenes

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E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model

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E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo

21 January 2018

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Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation

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E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts.

21 January 2018

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Amplification of the E2F1 transcription factor gene in the HEL erythroleukemia cell line

21 January 2018

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Increased gene copy number of the transcription factor E2F1 in malignant melanoma

21 January 2018

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E2F1 expression is related with the poor survival of lymph node-positive breast cancer patients treated with fluorouracil, doxorubicin and cyclophosphamide

21 January 2018

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Overexpression of E2F1 associated with LOH at RB locus and hyperphosphorylation of RB in non-small cell lung carcinoma

21 January 2018

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Distinct pattern of E2F1 expression in human lung tumours: E2F1 is upregulated in small cell lung carcinoma.

21 January 2018

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Up-regulation of transcriptional factor E2F1 in papillary and anaplastic thyroid cancers

21 January 2018

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Distinct expression patterns of the transcription factor E2F-1 in relation to tumour growth parameters in common human carcinomas.

21 January 2018

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Homologous recombination is a highly conserved determinant of the synergistic cytotoxicity between cisplatin and DNA topoisomerase I poisons

21 January 2018

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Deregulated E2F transcriptional activity in autonomously growing melanoma cells

21 January 2018

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Alterations of DeltaTA-p 73 splice transcripts during melanoma development and progression

21 January 2018

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Therapeutic window for melanoma treatment provided by selective effects of the proteasome on Bcl-2 proteins

21 January 2018

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Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications.

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Molecular requirements for epithelial-mesenchymal transition during tumor progression

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Epithelial-mesenchymal transitions in tumour progression

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Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions

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Role of the p53-homologue p73 in E2F1-induced apoptosis

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C-terminal p73 isoforms repress transcriptional activity of the human telomerase reverse transcriptase (hTERT) promoter

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High coexpression of both insulin-like growth factor receptor-1 (IGFR-1) and epidermal growth factor receptor (EGFR) is associated with shorter disease-free survival in resected non-small-cell lung cancer patients.

21 January 2018

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Transcriptional repression of the prosurvival endoplasmic reticulum chaperone GRP78/BIP by E2F1

21 January 2018

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The role of the EGFR signaling in tumor microenvironment.

21 January 2018

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Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials

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EGF-induced cell migration is mediated by ERK and PI3K/AKT pathways in cultured human lens epithelial cells

21 January 2018

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Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival.

21 January 2018

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Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling

21 January 2018

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An E2F1-dependent gene expression program that determines the balance between proliferation and cell death

21 January 2018

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

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Apaf-1 is a mediator of E2F-1-induced apoptosis

21 January 2018

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release_drm77z77ubcxjim2hj6ygr6wmm

21 January 2018

Identifiers

DOI

10.1093/JNCI/DJP458

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Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/drm77z77ubcxjim2hj6ygr6wmm