CD47 update: a multifaceted actor in the tumour microenvironment of potential therapeutic interest (Q28270624)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22774848%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

CD47 update: a multifaceted actor in the tumour microenvironment of potential therapeutic interest (English)

1 reference

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7 February 2020

3

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7 February 2020

Stephane Dedieu

4

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7 February 2020

author name string

E Sick

1

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7 February 2020

A Jeanne

2

1 reference

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7 February 2020

K Takeda

5

1 reference

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7 February 2020

L Martiny

6

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7 February 2020

language of work or name

English

0 references

publication date

1 December 2012

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British Journal of Pharmacology

7 February 2020

published in

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7 February 2020

volume

167

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7 February 2020

issue

7

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7 February 2020

page(s)

1415-1430

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A new disulfide-linked dimer of a single-chain antibody fragment against human CD47 induces apoptosis in lymphoid malignant cells via the hypoxia inducible factor-1α pathway

7 February 2020

cites work

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Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47

20 March 2017

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CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1

20 March 2017

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Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-CD47 interaction costimulates T-cell proliferation

20 March 2017

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The three Es of cancer immunoediting

20 March 2017

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Normal ligand binding and signaling by CD47 (integrin-associated protein) requires a long range disulfide bond between the extracellular and membrane-spanning domains

20 March 2017

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Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism

20 March 2017

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20 March 2017

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Role of CD47 as a marker of self on red blood cells

20 March 2017

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Regulation of tumor cell chemotaxis by type IV collagen is mediated by a Ca(2+)-dependent mechanism requiring CD47 and the integrin alpha(V)beta(3)

20 March 2017

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Subversion of monocyte functions by coxiella burnetii: impairment of the cross-talk between alphavbeta3 integrin and CR3

20 March 2017

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20 March 2017

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20 March 2017

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The vitronectin receptor and its associated CD47 molecule mediates proinflammatory cytokine synthesis in human monocytes by interaction with soluble CD23

20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand binding

20 March 2017

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20 March 2017

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20 March 2017

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Amyloid-β inhibits No-cGMP signaling in a CD36- and CD47-dependent manner

20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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7 April 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Thrombospondin-1 is an inhibitor of pharmacological activation of soluble guanylate cyclase

29 September 2017

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29 September 2017

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CD47 regulates collagen I-induced cyclooxygenase-2 expression and intestinal epithelial cell migration

29 September 2017

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CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

29 September 2017

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Thrombospondin-1-CD47 blockade and exogenous nitrite enhance ischemic tissue survival, blood flow and angiogenesis via coupled NO-cGMP pathway activation

29 September 2017

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29 September 2017

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Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeleton

29 September 2017

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Treatment of liver ischemia-reperfusion injury by limiting thrombospondin-1/CD47 signaling

29 September 2017

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Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.

29 September 2017

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Thrombospondin 1 and vasoactive agents indirectly alter tumor blood flow.

29 September 2017

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Association of CD47 with natural killer cell-mediated cytotoxicity of head-and-neck squamous cell carcinoma lines

29 September 2017

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Gene silencing of CD47 and antibody ligation of thrombospondin-1 enhance ischemic tissue survival in a porcine model: implications for human disease

29 September 2017

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29 September 2017

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Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts

29 September 2017

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Tumor stroma and regulation of cancer development

29 September 2017

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Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling

29 September 2017

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Antitumor activity of a monoclonal antibody against CD47 in xenograft models of human leukemia

29 September 2017

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The C-terminal CD47/IAP-binding domain of thrombospondin-1 prevents camptothecin- and doxorubicin-induced apoptosis in human thyroid carcinoma cells.

29 September 2017

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Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes

29 September 2017

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RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis

29 September 2017

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Post-translational regulation of expression and conformation of an immunoglobulin domain in yeast surface display

29 September 2017

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Thrombospondins, metallo proteases and thrombospondin receptors messenger RNA and protein expression in different tumour sublines of the Dunning prostate cancer model

29 September 2017

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Type 3 repeat/C-terminal domain of thrombospondin-1 triggers caspase-independent cell death through CD47/alphavbeta3 in promyelocytic leukemia NB4 cells

29 September 2017

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Apoptosis inducing bivalent single-chain antibody fragments against CD47 showed antitumor potency for multiple myeloma.

29 September 2017

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Platelet homeostasis is regulated by platelet expression of CD47 under normal conditions and in passive immune thrombocytopenia

29 September 2017

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Microglial phagocytosis of fibrillar beta-amyloid through a beta1 integrin-dependent mechanism.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

The C-terminal 26-residue peptide of serpin A1 stimulates proliferation of breast and liver cancer cells: role of protein kinase C and CD47.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Promotion of neurite and filopodium formation by CD47: roles of integrins, Rac, and Cdc42.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

A bivalent single-chain Fv fragment against CD47 induces apoptosis for leukemic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Cholesterol-independent interactions with CD47 enhance alphavbeta3 avidity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

CD47 mediates killing of breast tumor cells via Gi-dependent inhibition of protein kinase A.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Resistance of B16 melanoma cells to CD47-induced negative regulation of motility as a result of aberrant N-glycosylation of SHPS-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gbetagamma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

CD47 and the 19 kDa Interacting Protein-3 (BNIP3) in T Cell Apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Mechanisms of CD47-induced caspase-independent cell death in normal and leukemic cells: link between phosphatidylserine exposure and cytoskeleton organization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Thrombospondins: multifunctional regulators of cell interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Molecular cloning of a novel human gene (SIRP-B2) which encodes a new member of the SIRP/SHPS-1 protein family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Thrombospondin-1 inhibits TCR-mediated T lymphocyte early activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

SHPS-1 induces aggregation of Ba/F3 pro-B cells via an interaction with CD47.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Increased Escherichia coli phagocytosis in neutrophils that have transmigrated across a cultured intestinal epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Integrin-associated protein stimulates alpha2beta1-dependent chemotaxis via Gi-mediated inhibition of adenylate cyclase and extracellular-regulated kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Role of cholesterol in formation and function of a signaling complex involving alphavbeta3, integrin-associated protein (CD47), and heterotrimeric G proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

CD44 occupancy prevents macrophage multinucleation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Thrombospondin modulates alpha v beta 3 function through integrin-associated protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Integrin-associated protein immunoglobulin domain is necessary for efficient vitronectin bead binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

CD47 mediates post-adhesive events required for neutrophil migration across polarized intestinal epithelia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Transendothelial migration of neutrophils involves integrin-associated protein (CD47)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Drp1 mediates caspase-independent type III cell death in normal and leukemic cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Melanoma x macrophage hybrids with enhanced metastatic potential.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

A 50-kDa integrin-associated protein is required for integrin-regulated calcium entry in endothelial cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Thrombospondin mediates calcium mobilization in fibroblasts via its Arg-Gly-Asp and carboxyl-terminal domains

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Regulation of integrin function by CD47 ligands. Differential effects on alpha vbeta 3 and alpha 4beta1 integrin-mediated adhesion

2 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Mechanism of CD47-induced alpha4beta1 integrin activation and adhesion in sickle reticulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Thrombospondin/CD47 interaction: a pathway to generate regulatory T cells from human CD4+ CD25- T cells in response to inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Ligation of CD47 during monocyte differentiation into dendritic cells results in reduced capacity for interleukin-12 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Induction of integrin-associated protein (IAP) mRNA expression during memory consolidation in rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Autocrine regulation of T cell motility by calreticulin-thrombospondin-1 interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

The role of CD47 in neutrophil transmigration. Increased rate of migration correlates with increased cell surface expression of CD47.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Signal regulatory protein (SIRPalpha), a cellular ligand for CD47, regulates neutrophil transmigration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

The mechanism of CD47-dependent killing of T cells: heterotrimeric Gi-dependent inhibition of protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

CD47 augments Fas/CD95-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

CD47 promotes neuronal development through Src- and FRG/Vav2-mediated activation of Rac and Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Novel CD47-dependent intercellular adhesion modulates cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Mitochondrial dysfunction in CD47-mediated caspase-independent cell death: ROS production in the absence of cytochrome c and AIF release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Activation of CD47 receptors causes histamine secretion from mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

C-terminal peptide of thrombospondin-1 induces platelet aggregation through the Fc receptor gamma-chain-associated signaling pathway and by agglutination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Increasing Survival of Ischemic Tissue by Targeting CD47

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.02099.X

Mechanical regulation of proteoglycan synthesis in normal and osteoarthritic human articular chondrocytes--roles for alpha5 and alphaVbeta5 integrins.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3514757

Absence of CD47 in protein 4.2-deficient hereditary spherocytosis in man: an interaction between the Rh complex and the band 3 complex

27 November 2018

1 reference

12 December 2020

Thrombospondin-1 C-terminal-derived peptide protects thyroid cells from ceramide-induced apoptosis through the adenylyl cyclase pathway

1 reference

12 December 2020

Osteoclast formation is strongly reduced both in vivo and in vitro in the absence of CD47/SIRPalpha-interaction

1 reference

12 December 2020

Interactions between CD47 and thrombospondin reduce inflammation

1 reference

12 December 2020

CD47 engagement inhibits cytokine production and maturation of human dendritic cells

1 reference

12 December 2020

A spontaneous murine melanoma lung metastasis comprised of host x tumor hybrids

1 reference

12 December 2020

Integrin-associated protein/CD47 regulates motile activity in human B-cell lines through CDC42

1 reference

12 December 2020

CD47 is a ligand for rat macrophage membrane signal regulatory protein SIRP (OX41) and human SIRPalpha 1

1 reference

12 December 2020

CD47, a ligand for the macrophage fusion receptor, participates in macrophage multinucleation

1 reference

12 December 2020

Identification of a receptor candidate for the carboxyl-terminal cell binding domain of thrombospondins

1 reference

12 December 2020

Stimulation of platelet activation and aggregation by a carboxyl-terminal peptide from thrombospondin binding to the integrin-associated protein receptor

1 reference

12 December 2020

T cell stimulation via CD47: agonistic and antagonistic effects of CD47 monoclonal antibody 1/1A4

1 reference

12 December 2020

Role of CD47 in the induction of human naive T cell anergy

1 reference

12 December 2020

The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi

1 reference

12 December 2020

Beta 1 integrin- and proteoglycan-mediated stimulation of T lymphoma cell adhesion and mitogen-activated protein kinase signaling by thrombospondin-1 and thrombospondin-1 peptides

1 reference

12 December 2020

Human thrombospondin's (TSP-1) C-terminal domain opens to interact with the CD-47 receptor: a molecular modeling study

1 reference

12 December 2020

CD47 regulation of epithelial cell spreading and migration, and its signal transduction

1 reference

12 December 2020

10.1111/J.1476-5381.2012.02099.X

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22774848%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22774848%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

22774848

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22774848%20AND%20SRC:MED&resulttype=core&format=json