The acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3β-dependent, protein kinase C (PKC)-mediated endocytic trafficking. (Q28272135)

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English	The acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3β-dependent, protein kinase C (PKC)-mediated endocytic trafficking.	scientific article

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9 February 2020

The acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3β-dependent, protein kinase C (PKC)-mediated endocytic trafficking (English)

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9 February 2020

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Demetra Orthodoxou

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9 February 2020

Haley E Melikian

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9 February 2020

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Luke Gabriel

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9 February 2020

Anatoli Lvov

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9 February 2020

Ann R Rittenhouse

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William R Kobertz

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30 July 2012

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9 February 2020

Journal of Biological Chemistry

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9 February 2020

32354-32366

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9 February 2020

The plasma membrane-associated GTPase Rin interacts with the dopamine transporter and is required for protein kinase C-regulated dopamine transporter trafficking

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20 March 2017

Molecular background of leak K+ currents: two-pore domain potassium channels

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20 March 2017

Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels

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20 March 2017

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

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Homeostatic plasticity and NMDA receptor trafficking

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20 March 2017

Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals

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20 March 2017

Interaction with 14-3-3 proteins promotes functional expression of the potassium channels TASK-1 and TASK-3

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20 March 2017

p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1

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20 March 2017

Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: volatile anesthetics and neurotransmitters share a molecular site of action

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20 March 2017

Calyculin A-induced vimentin phosphorylation sequesters 14-3-3 and displaces other 14-3-3 partners in vivo

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20 March 2017

Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3

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20 March 2017

A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity

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20 March 2017

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

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20 March 2017

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20 March 2017

The retention factor p11 confers an endoplasmic reticulum-localization signal to the potassium channel TASK-1

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20 March 2017

Motoneurons express heteromeric TWIK-related acid-sensitive K+ (TASK) channels containing TASK-1 (KCNK3) and TASK-3 (KCNK9) subunits

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20 March 2017

Receptor trafficking and synaptic plasticity

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6 April 2017

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NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

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29 September 2017

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29 September 2017

Regulation of opioid receptors by endocytic membrane traffic: mechanisms and translational implications

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29 September 2017

Constitutive endocytic recycling and protein kinase C-mediated lysosomal degradation control K(ATP) channel surface density

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29 September 2017

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29 September 2017

The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice

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29 September 2017

TASK channel deletion in mice causes primary hyperaldosteronism

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29 September 2017

Regulation of epithelial Na+ channels by aldosterone: role of Sgk1.

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29 September 2017

Regulatory mechanisms of AMPA receptors in synaptic plasticity

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29 September 2017

Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors

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AMPA and NMDA glutamate receptor trafficking: multiple roads for reaching and leaving the synapse

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29 September 2017

Inhibition of a background potassium channel by Gq protein alpha-subunits

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29 September 2017

Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization

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29 September 2017

Two-pore domain potassium channels: new sites of local anesthetic action and toxicity

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29 September 2017

14-3-3 proteins modulate the expression of epithelial Na+ channels by phosphorylation-dependent interaction with Nedd4-2 ubiquitin ligase.

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29 September 2017

Presynaptic K+ channels: electrifying regulators of synaptic terminal excitability.

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29 September 2017

The TASK family: two-pore domain background K+ channels

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29 September 2017

Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane

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29 September 2017

Synaptic plasticity and AMPA receptor trafficking

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29 September 2017

Functional expression of TASK-1/TASK-3 heteromers in cerebellar granule cells

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29 September 2017

Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels

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29 September 2017

The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines.

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29 September 2017

Mechanisms of GABAA receptor assembly and trafficking: implications for the modulation of inhibitory neurotransmission.

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29 September 2017

NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity

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29 September 2017

TASK-1 is a highly modulated pH-sensitive 'leak' K(+) channel expressed in brainstem respiratory neurons

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29 September 2017

Cns distribution of members of the two-pore-domain (KCNK) potassium channel family.

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29 September 2017

Activation of MAPK by TRH requires clathrin-dependent endocytosis and PKC but not receptor interaction with beta-arrestin or receptor endocytosis

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29 September 2017

Molecular and functional properties of two-pore-domain potassium channels.

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29 September 2017

The TASK-1 two-pore domain K+ channel is a molecular substrate for neuronal effects of inhalation anesthetics.

1 reference

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29 September 2017

A functional role for the two-pore domain potassium channel TASK-1 in cerebellar granule neurons

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29 September 2017

TASK-1, a two-pore domain K+ channel, is modulated by multiple neurotransmitters in motoneurons

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29 September 2017

Sequence and function of the two P domain potassium channels: implications of an emerging superfamily

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29 September 2017

Protein kinase A is central for forward transport of two-pore domain potassium channels K2P3.1 and K2P9.1.

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2 June 2018

Rapid endocytosis provides restricted somatic expression of a K+ channel in central neurons.

1 reference

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2 June 2018

A role for TASK-1 (KCNK3) channels in the chemosensory control of breathing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463364

2 June 2018

Dopamine transporter endocytic determinants: carboxy terminal residues critical for basal and PKC-stimulated internalization.

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2 June 2018

Contribution of TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 channels to the control of activity modes in thalamocortical neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463364

2 June 2018

A leucine-based motif mediates the endocytosis of vesicular monoamine and acetylcholine transporters

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2 June 2018

Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes

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2 June 2018

Formation of functional heterodimers between the TASK-1 and TASK-3 two-pore domain potassium channel subunits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.391458

21 January 2018

Differential effects of volatile and intravenous anesthetics on the activity of human TASK-1.

1 reference

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21 January 2018

Forward Transport of K2p3.1: mediation by 14-3-3 and COPI, modulation by p11.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.391458

21 January 2018

Activation of protein kinase C epsilon inhibits the two-pore domain K+ channel, TASK-1, inducing repolarization abnormalities in cardiac ventricular myocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.391458

21 January 2018

Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.391458

21 January 2018

Intracellular traffic of the K+ channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.391458

21 January 2018

Inhibition of TASK1-like channels by muscarinic receptor stimulation in rat adrenal medullary cells

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27 November 2018

Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures.

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27 November 2018

14-3-3 proteins: a number of functions for a numbered protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22846993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

14-3-3 isoforms are induced by aldosterone and participate in its regulation of epithelial sodium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/22846993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G(alpha)q-mediated regulation of TASK3 two-pore domain potassium channels: the role of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/22846993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.391458

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846993%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846993%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22846993%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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