Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression (Q28273723)

Europe PubMed Central

title

Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression (English)

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Robert Busch

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Cornelia H Rinderknecht

2

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Sujin Roh

3

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Andrew W Lee

4

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James J Harding

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Timo Burster

6

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Tara M C Hornell

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Elizabeth D Mellins

MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

8

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language of work or name

English

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publication date

October 2005

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published in

Immunological Reviews

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volume

207

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page(s)

242-60

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cites work

1 reference

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B lymphocytes secrete antigen-presenting vesicles

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Developing and shedding inhibitions: how MHC class II molecules reach maturity

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Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

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Mediation by HLA-DM of dissociation of peptides from HLA-DR.

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Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes

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A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex

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Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells

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21 January 2018

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Secondary structure composition and pH-dependent conformational changes of soluble recombinant HLA-DM.

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Determination of the HLA-DM interaction site on HLA-DR molecules

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HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules

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Functional analysis of tryptophans alpha 62 and beta 120 on HLA-DM.

21 January 2018

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Point Mutations in or Near the Antigen-Binding Groove of HLA-DR3 Implicate Class II-Associated Invariant Chain Peptide Affinity as a Constraint on MHC Class II Polymorphism

21 January 2018

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HLA-DM recognizes the flexible conformation of major histocompatibility complex class II.

21 January 2018

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Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain.

21 January 2018

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Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysis

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Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs

21 January 2018

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Binding interactions between peptides and proteins of the class II major histocompatibility complex

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Binding affinity independent contribution of peptide length to the stability of peptide-HLA-DR complexes in live antigen presenting cells

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Identification of destabilizing residues in HLA class II-selected bacteriophage display libraries edited by HLA-DM.

21 January 2018

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Ligand exchange of major histocompatibility complex class II proteins is triggered by H-bond donor groups of small molecules

21 January 2018

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"Chemical analogues" of HLA-DM can induce a peptide-receptive state in HLA-DR molecules

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Energetic asymmetry among hydrogen bonds in MHC class II*peptide complexes

21 January 2018

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Structural factors contributing to DM susceptibility of MHC class II/peptide complexes

21 January 2018

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Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules

21 January 2018

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Formation of two peptide/MHC II isomers is catalyzed differentially by HLA-DM.

21 January 2018

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Regulated expression of human histocompatibility leukocyte antigen (HLA)-DO during antigen-dependent and antigen-independent phases of B cell development

21 January 2018

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Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Empty and peptide-loaded class II major histocompatibility complex proteins produced by expression in Escherichia coli and folding in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

The kinetic basis of peptide exchange catalysis by HLA-DM

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Formation of a highly peptide-receptive state of class II MHC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Kinetics of peptide binding to the class II MHC protein I-Ek

21 January 2018

1 reference

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Peptide register shifting within the MHC groove: theory becomes reality

21 January 2018

1 reference

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Kinetics of registry selection of chimeric peptides binding to MHC II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

DM determines the cryptic and immunodominant fate of T cell epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Relationship between kinetic stability and immunogenicity of HLA-DR4/peptide complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Intracellular transport of class II MHC molecules directed by invariant chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CL

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Rheumatoid arthritis (RA)-associated HLA-DR alleles form less stable complexes with class II-associated invariant chain peptide than non-RA-associated HLA-DR alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Effect of decreasing the affinity of the class II-associated invariant chain peptide on the MHC class II peptide repertoire in the presence or absence of H-2M.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Invariant chain controls H2-M proteolysis in mouse splenocytes and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DM

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Relaxed DM requirements during class II peptide loading and CD4+ T cell maturation in BALB/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Modulation of peptide-dependent allospecific epitopes on HLA-DR4 molecules by HLA-DM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Conformational alterations during biosynthesis of HLA-DR3 molecules controlled by invariant chain and HLA-DM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Irreversible association of peptides with class II MHC molecules in living cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Stability of empty and peptide-loaded class II major histocompatibility complex molecules at neutral and endosomal pH: comparison to class I proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Antigen presentation mediated by recycling of surface HLA-DR molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

MHC class II molecules traffic into lipid rafts during intracellular transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Upregulation of the CLIP self peptide on mature dendritic cells antagonizes T helper type 1 polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

The role of self-peptides in the development of CD4+ CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

T helper subset differentiation in the absence of invariant chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

The functional role of class II-associated invariant chain peptide (CLIP) in its ability to variably modulate immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Innate host defense of the lung: effects of lung-lining fluid pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

The down-regulation of HLA-DM gene expression in rheumatoid arthritis is not related to their promoter polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Membrane specializations and endosome maturation in dendritic cells and B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Mobilizing dendritic cells for tolerance, priming, and chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Interleukin-10 down-regulates MHC class II alphabeta peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

The human cytomegalovirus protein UL16 mediates increased resistance to natural killer cell cytotoxicity through resistance to cytolytic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Bordetella pertussis infection of primary human monocytes alters HLA-DR expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Inhibition of cell surface MHC class II expression by Salmonella

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

T-cell engagement of dendritic cells rapidly rearranges MHC class II transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

pH-dependent peptide binding properties of the type I diabetes-associated I-Ag7 molecule: rapid release of CLIP at an endosomal pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

MHC Class II Expression Is Regulated in Dendritic Cells Independently of Invariant Chain Degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2005.00306.X

Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules

21 January 2018

1 reference

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10.1111/J.0105-2896.2005.00306.X

21 January 2018

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

2110224

2110224

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference