A historical sketch of the discovery and development of HIV-1 integrase inhibitors (Q28274166)

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Retroviral DNA integration directed by HIV integration protein in vitro

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Inhibition of HIV-1 integration protein by aurintricarboxylic acid monomers, monomer analogs, and polymer fractions

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Inhibitors of human immunodeficiency virus integrase

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Inhibition of human immunodeficiency virus integrase by bis-catechols

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Isolation and characterization of novel human immunodeficiency virus integrase inhibitors from fungal metabolites

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Depletion of latent HIV-1 infection in vivo: a proof-of-concept study

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Valproic acid and HIV-1 latency: beyond the sound bite

21 April 2017

1 reference

https://api.crossref.org/works/10.1517/13543784.15.12.1507

Integrase inhibitors to treat HIV/AIDS.

21 April 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

In vivo evidence for instability of episomal human immunodeficiency virus type 1 cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

HIV-1 integrase inhibitors: 2003-2004 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Design, synthesis and biological evaluation of heteroaryl diketohexenoic and diketobutanoic acids as HIV-1 integrase inhibitors endowed with antiretroviral activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Emerging drug targets for antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Integration of human immunodeficiency virus type 1 DNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Gene therapy for human immunodeficiency virus infection: genetic antiviral strategies and targets for intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Stem cells as vehicles for gene therapy: novel strategy for HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Anti-HIV therapy with antisense oligonucleotides and ribozymes: realistic approaches or expensive myths?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

The biochemistry of gene therapy for AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Alternate strand DNA triple helix-mediated inhibition of HIV-1 U5 long terminal repeat integration in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

A molecular mechanics and dynamics study of alternate triple-helices involving the integrase-binding site of the HIV-1 virus and oligonucleotides having a 3'-3' internucleotide junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Targeting sites within HIV-1 cDNA with a DNA-cleaving ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Anti-HIV effects of chloroquine: mechanisms of inhibition and spectrum of activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Inhibition of human immunodeficiency virus type-1 integrase by curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Inhibition of Vpr-induced cell cycle abnormality by quercetin: a novel strategy for searching compounds targeting Vpr.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Synthesis and HIV-1 integrase inhibitory activities of catechol and bis-catechol derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Structure-activity relationships of HIV-1 integrase inhibitors--enzyme-ligand interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Dicaffeoylquinic and dicaffeoyltartaric acids are selective inhibitors of human immunodeficiency virus type 1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Catechol-substituted L-chicoric acid analogues as HIV integrase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Design and development of integrase inhibitors as anti-HIV agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Dicaffeoyltartaric acid analogues inhibit human immunodeficiency virus type 1 (HIV-1) integrase and HIV-1 replication at nontoxic concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Patented HIV-1 integrase inhibitors (1998-2005).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

QSAR of HIV-1 integrase inhibitors by genetic function approximation method

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

HIV-1 integrase inhibitory phenylpropanoid glycosides from Clerodendron trichotomum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

A novel assay for the DNA strand-transfer reaction of HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Integracides: tetracyclic triterpenoid inhibitors of HIV-1 integrase produced by Fusarium sp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Metal-dependent inhibition of HIV-1 integrase by beta-diketo acids and resistance of the soluble double-mutant (F185K/C280S).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Design and synthesis of 8-hydroxy-[1,6]naphthyridines as novel inhibitors of HIV-1 integrase in vitro and in infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Novel HIV-1 integrase inhibitors derived from quinolone antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Discovery of a small-molecule HIV-1 integrase inhibitor-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

HIV-1 inactivation by nucleic acid aptamers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Targeting HIV-1 integrase with aptamers selected against the purified RNase H domain of HIV-1 RT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Identification of heavy metal complexes of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a voltammetric approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Seeing is believing: structure of the catalytic domain of HIV-1 integrase in complex with human LEDGF/p75.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Retroviral integrases and their cousins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Antiretroviral therapy with protease inhibitors has an early, immune reconstitution-independent beneficial effect on Candida virulence and oral candidiasis in human immunodeficiency virus-infected subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

In vitro inhibitory activity of citreoviridin against HIV-1 and an HIV-associated opportunist: Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Residual viraemia in subjects with chronic HIV infection and viral load < 50 copies/ml: the impact of highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Can HIV be Cured? Mechanisms of HIV persistence and strategies to combat it.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Expression of latent HAART-persistent HIV type 1 induced by novel cellular activating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

Binding Mode Prediction of Strand Transfer HIV-1 Integrase Inhibitors Using Tn5 Transposase as a Plausible Surrogate Model for HIV-1 Integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.15.12.1507

10.1517/13543784.15.12.1507

21 January 2018

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

890785

OpenCitations bibliographic resource ID

890785

1 reference