SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation (Q28275010)

David B Lombard

6

0 references

Asish K Saha

Asish K Saha

13

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Matthew D. Hirschey

Matthew D Hirschey

1

0 references

James Bain

James R Bain

15

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Neil B Ruderman

Neil B Ruderman

14

0 references

Eric Verdin

Eric Verdin

20

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C. Ronald Kahn

19

C Ronald Kahn

0 references

Christopher B Newgard

16

Christopher B Newgard

0 references

Tadahiro Shimazu

2

Tadahiro Shimazu

0 references

Olga R Ilkayeva

10

Olga R Ilkayeva

0 references

Enxuan Jing

4

Enxuan Jing

0 references

Robert V Farese

17

Robert V Farese

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author name string

Eric Goetzman

3

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Bjoern Schwer

5

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Charles Harris

8

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Sudha Biddinger

9

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Robert D Stevens

11

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Yu Li

12

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Frederick W Alt

Conserved metabolic regulatory functions of sirtuins

18

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language of work or name

English

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publication date

4 March 2010

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published in

Nature

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volume

464

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issue

7285

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page(s)

121-5

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Medium-chain acyl-CoA dehydrogenase deficiency in gene-targeted mice

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Targeted disruption of mouse long-chain acyl-CoA dehydrogenase gene reveals crucial roles for fatty acid oxidation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Adipose tissue gene expression profiles in ob/ob mice treated with leptin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Assays of fatty acid beta-oxidation activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Sirtuins as potential targets for metabolic syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Evidence for impaired gluconeogenesis in very long-chain acyl-CoA dehydrogenase-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Nonalcoholic fatty liver disease and risk of future cardiovascular events among type 2 diabetic patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Database of mRNA gene expression profiles of multiple human organs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Mouse models for disorders of mitochondrial fatty acid beta-oxidation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Regulation of hepatic fatty acid oxidation and ketone body production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Calorie restriction alters mitochondrial protein acetylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Mammalian mitochondrial beta-oxidation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Significant correlations between severe fatty liver and risk factors for metabolic syndrome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Gestational, pathologic and biochemical differences between very long-chain acyl-CoA dehydrogenase deficiency and long-chain acyl-CoA dehydrogenase deficiency in the mouse

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841477

Lipid oxidation is reduced in obese human skeletal muscle

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20203611

12 December 2020

inferred from PubMed ID database lookup

Fluorometric assay of acyl-CoA dehydrogenases in normal and mutant human fibroblasts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20203611

12 December 2020

inferred from PubMed ID database lookup

Nonalcoholic fatty liver disease is a risk factor for type 2 diabetes in middle-aged Japanese men

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20203611

12 December 2020

inferred from PubMed ID database lookup

ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Hepatocellular influx of [14C]oleate reflects membrane transport rather than intracellular metabolism or binding

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Isolation of mitochondria from tissues and cells by differential centrifugation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Purification of a crude mitochondrial fraction by density-gradient centrifugation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Acetylation of mitochondrial proteins

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08778

7 January 2021

Identifiers

DOI

10.1038/NATURE08778

1 reference

Dimensions Publication ID

267144

1032028240

0 references

267144

1 reference

1 reference

1 reference