Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans (Q28276159)

7

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Eric Hoffman

6

object named as

Eric P Hoffman

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Joseph A. Houmard

10

object named as

Joseph A Houmard

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author name string

Matthew W Hulver

1

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Jason R Berggren

2

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Michael J Carper

3

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Makoto Miyazaki

4

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James M Ntambi

5

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Robert Stevens

8

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G Lynis Dohm

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

9

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language of work or name

English

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publication date

October 2005

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published in

Cell Metabolism

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volume

2

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issue

4

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page(s)

251-61

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cites work

1 reference

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Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle

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Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice

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The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1

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Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle

7 April 2017

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Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.

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Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases

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Regulation of stearoyl-CoA desaturases and role in metabolism

29 September 2017

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Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

29 September 2017

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Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

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Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues

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Intramuscular lipid content is increased in obesity and decreased by weight loss

29 September 2017

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Role of skeletal muscle in thiazolidinedione insulin sensitizer (PPARgamma agonist) action

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Skeletal muscle peroxisome proliferator- activated receptor-gamma expression in obesity and non- insulin-dependent diabetes mellitus

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Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms

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Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects

29 September 2017

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The regulation of stearoyl-CoA desaturase (SCD).

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An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects

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Mechanism of rat liver microsomal stearyl-CoA desaturase. Studies of the substrate specificity, enzyme-substrate interactions, and the function of lipid

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Reduced lipid oxidation in skeletal muscle from type 2 diabetic subjects may be of genetic origin: evidence from cultured myotubes

29 September 2017

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Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta

2 June 2018

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Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle

2 June 2018

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Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity

2 June 2018

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Protein kinase C modulates insulin action in human skeletal muscle

2 June 2018

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Reversal of chronic alterations of skeletal muscle protein kinase C from fat-fed rats by BRL-49653.

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PPAR-gamma gene expression is elevated in skeletal muscle of obese and type II diabetic subjects

2 June 2018

1 reference

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Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures

2 June 2018

1 reference

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Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase

2 June 2018

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Tandem mass spectrometry: a new method for acylcarnitine profiling with potential for neonatal screening for inborn errors of metabolism

2 June 2018

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Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

2 June 2018

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Glucose oversupply increases Delta9-desaturase expression and its metabolites in rat skeletal muscle

27 November 2018

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Skeletal muscle lipid metabolism with obesity

27 November 2018

1 reference

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Response of rat muscle to acute resistance exercise defined by transcriptional and translational profiling.

27 November 2018

1 reference

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Adiponectin is not altered with exercise training despite enhanced insulin action

27 November 2018

1 reference

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Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285571

A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285571

Peroxisome proliferator-activated receptor (PPAR)-alpha activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-gamma activation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285571

Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285571

Interaction of malonyl-CoA and related compounds with mitochondria from different rat tissues. Relationship between ligand binding and inhibition of carnitine palmitoyltransferase I.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4285571

Lipid content and fatty acid composition of heart and muscle of the BIO 82.62 cardiomyopathic hamster

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16213227

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fat content in individual muscle fibers of lean and obese subjects

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16213227

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanism of insulin resistance in A-ZIP/F-1 fatless mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16213227

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2005.09.002

1 reference

354176

354176

1 reference

1 reference

1 reference