Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells (Q28277030)

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S Tamura

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E Buchdunger

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S Ohno

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G M Segal

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S Fanning

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J Zimmermann

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N B Lydon

https://scigraph.springernature.com/pub.10.1038/nm0596-561

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language of work or name

English

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publication date

May 1996

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published in

Nature Medicine

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volume

2

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page(s)

561-6

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issue

5

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exact match

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Interferon alfa-2a as compared with conventional chemotherapy for the treatment of chronic myeloid leukemia

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Autografting in chronic myeloid leukaemia

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Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

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Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

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Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

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Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).

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v-abl causes hematopoietic disease distinct from that caused by bcr-abl

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Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

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Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

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Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

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Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors

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Tyrosine kinase inhibition: an approach to drug development

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Modelling study of protein kinase inhibitors: binding mode of staurosporine and origin of the selectivity of CGP 52411

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Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

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Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

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The nuclear tyrosine kinase c-Abl negatively regulates cell growth

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Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction

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Lineage-specific requirement of c-abl function in normal hematopoiesis

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Platelet-derived growth factor: mechanism of action and possible in vivo function

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Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines

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Selective growth response to IL-3 of a human leukaemic cell line with megakaryoblastic features.

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Differentiation in erythroleukemic cells and their somatic hybrids

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RETRACTED: 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity

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RETRACTED: Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class

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cdc2 is a component of the M phase-specific histone H1 kinase: evidence for identity with MPF

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Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor

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Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

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A comparison of the response of human lung carcinoma xenografts to vindesine and vincristine

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Repression of Fanconi anemia gene (FACC) expression inhibits growth of hematopoietic progenitor cells

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