Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (Q28279053)

12

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author name string

P Carmeliet

1

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Y Dor

2

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J M Herbert

3

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D Fukumura

4

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K Brusselmans

5

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M Dewerchin

6

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M Neeman

7

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F Bono

8

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R Abramovitch

9

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P Maxwell

10

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C J Koch

11

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R K Jain

14

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D Collen

15

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E Keshert

16

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E Keshet

Oxygen sensing and molecular adaptation to hypoxia

17

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language of work or name

English

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publication date

30 July 1998

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published in

Nature

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volume

394

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page(s)

485-90

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issue

6692

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cites work

1 reference

7 January 2021

Transcriptional regulation by hypoxia-inducible factor 1 molecular mechanisms of oxygen homeostasis

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

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Ischemia-driven angiogenesis

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p21--negative regulator of the cell cycle

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p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

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The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications

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Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression

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Multiple pathways control cell growth and transformation: overlapping and independent activities of p53 and p21Cip1/WAF1/Sdi1.

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Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

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Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

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Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

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Regulation of proliferation-survival decisions during tumor cell hypoxia

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Growth factors as survival factors: regulation of apoptosis

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Cytokines inhibit p53-mediated apoptosis but not p53-mediated G1 arrest

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The influence of tumor blood flow and microenvironmental factors on the efficacy of radiation, drugs and localized hyperthermia

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Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

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7 January 2021

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

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7 January 2021

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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Analysis of subcutaneous angiogenesis by gradient echo magnetic resonance imaging.

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Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide].

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Involvement of u-PA in the anti-apoptotic activity of TGFbeta for vascular smooth muscle cells

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7 January 2021

Identifiers

DOI

10.1038/28867

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

413115

1020992380

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Fatcat ID

release_7ex6g5vomzeatdklrth6w6hqra

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7ex6g5vomzeatdklrth6w6hqra

24 November 2022

mapped directly with Wikidata item

413115

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference