Genotyping of human cytochrome P450 2A6 (CYP2A6), a nicotine C-oxidase (Q28289652)

2

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A Rautio

3

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M L Bernal

4

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B Sinues

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M L Dahl

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J H Stengård

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O Pelkonen

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H Raunio

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M Ingelman-Sundberg

Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility--a review

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language of work or name

English

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publication date

6 November 1998

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published in

FEBS Letters

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volume

438

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issue

3

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page(s)

201-5

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cites work

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The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

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Human cytochrome P450IIA3: cDNA sequence, role of the enzyme in the metabolic activation of promutagens, comparison to nitrosamine activation by human cytochrome P450IIE1.

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Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

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Human Kidney Methoxyflurane and Sevoflurane Metabolism

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Metabolism of nicotine by human liver microsomes: stereoselective formation of trans-nicotine N'-oxide

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A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin

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Hepatitis A impairs the function of human hepatic CYP2A6 in vivo.

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Effective amplification of long targets from cloned inserts and human genomic DNA

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Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity

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Expression and alternative splicing of the cytochrome P-450 CYP2A7

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Influence of pharmacogenetics on drug disposition and response

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Nicotine metabolism defect reduces smoking.

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The Gerhard Zbinden Memorial Lecture. Genetic polymorphism of drug metabolizing enzymes. Implications for toxicity of drugs and other xenobiotics.

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Comparison of a novel thin-layer chromatographic-fluorescence detection method with a spectrofluorometric method for the determination of 7-hydroxycoumarin in human urine

7 January 2021

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Interindividual variability of coumarin 7-hydroxylation in a Turkish population

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High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans

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Nomenclature for human CYP2D6 alleles.

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A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502).

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CYP2A6 gene polymorphism and risk of liver cancer and cirrhosis

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Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population

7 January 2021

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Twenty-year trends in coronary risk factors in north Karelia and in other areas of Finland

7 January 2021

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