Targeting NF-kappaB in hematologic malignancies (Q28299055)

Europe PubMed Central

title

Targeting NF-kappaB in hematologic malignancies (English)

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G Kroemer

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Pierre Fenaux

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object named as

P Fenaux

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author name string

T Braun

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G Carvalho

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C Fabre

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J Grosjean

Cell Death & Differentiation

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language of work or name

English

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publication date

May 2006

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published in

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volume

13

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page(s)

748-58

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issue

5

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cites work

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Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells

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Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells

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Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

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NF-kappa B as a central mediator in the induction of TGF-beta in monocytes from patients with idiopathic myelofibrosis: an inflammatory response beyond the realm of homeostasis

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Novel therapeutic approaches for multiple myeloma

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Signaling pathways activated by daunorubicin

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Apoptotic resistance to ionizing radiation in pediatric B-precursor acute lymphoblastic leukemia frequently involves increased NF-kappaB survival pathway signaling.

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Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia

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Constitutive NF-κB/Rel Activation in Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL)

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NF-kappaB constitutes a potential therapeutic target in high-risk myelodysplastic syndrome

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Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

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Detection by the fluorescence in situ hybridization technique of MYC translocations in paraffin-embedded lymphoma biopsy samples

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Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells

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A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.

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Autocrine VEGF mediates the antiapoptotic effect of CD154 on CLL cells

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A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation

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Expression and prognostic significance of Bcl-2 family proteins in myelodysplastic syndromes

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Increased IkappaB kinase activity is associated with activated NF-kappaB in acute myeloid blasts

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Role for the nuclear factor kappaB pathway in transforming growth factor-beta1 production in idiopathic myelofibrosis: possible relationship with FK506 binding protein 51 overexpression

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Structure and functions of the 20S and 26S proteasomes

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Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma

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