An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis (Q28301787)

2

Ikuyo Kou

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Hideki Kizawa

1

Hideki Kizawa

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Aritoshi Iida

3

Aritoshi Iida

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Yoshinari Miyamoto

5

Yoshinari Miyamoto

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author name string

Akihiro Sudo

4

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Akira Fukuda

6

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Akihiko Mabuchi

7

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Akihiro Kotani

8

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Akira Kawakami

9

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Seizo Yamamoto

10

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Atsumasa Uchida

11

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Kozo Nakamura

12

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Kohei Notoya

13

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Yusuke Nakamura

Identification and characterization of asporin. a novel member of the leucine-rich repeat protein family closely related to decorin and biglycan

14

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language of work or name

English

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publication date

February 2005

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published in

Nature Genetics

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volume

37

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issue

2

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page(s)

138-44

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cites work

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Expression pattern and gene characterization of asporin. a newly discovered member of the leucine-rich repeat protein family

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Identification of sequence polymorphisms in two sulfation-related genes, PAPSS2 and SLC26A2, and an association analysis with knee osteoarthritis

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Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro

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Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic ATDC5 cells

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Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5.

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Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis

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TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage

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Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

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Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney

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Calcium-binding properties of osteopontin derived from non-osteogenic sources

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Investigation of the association of the CRTM and CRTL1 genes with radiographically evident osteoarthritis in subjects from the Rotterdam study.

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Adjacent genes, for COL2A1 and the vitamin D receptor, are associated with separate features of radiographic osteoarthritis of the knee

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Association between a single-nucleotide polymorphism in the promoter of the human interleukin-3 gene and rheumatoid arthritis in Japanese patients, and maximum-likelihood estimation of combinatorial effect that two genetic loci have on susceptibilit

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Association of the interleukin-1 gene cluster on chromosome 2q13 with knee osteoarthritis

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7 January 2021

Fibromodulin-null murine knee joints display increased incidences of osteoarthritis and alterations in tissue biochemistry

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7 January 2021

Abnormal collagen fibrils in tendons of biglycan/fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis

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7 January 2021

Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair

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7 January 2021

Decorin is a Zn2+ metalloprotein

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Decorin binds fibrinogen in a Zn2+-dependent interaction

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7 January 2021

Identification of sequence polymorphisms of the COMP (cartilage oligomeric matrix protein) gene and association study in osteoarthrosis of the knee and hip joints

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7 January 2021