SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation (Q28302907)

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19 January 2020

title

SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation (English)

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19 January 2020

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1 reference

3

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19 January 2020

Marie Sofie Yoo Larsen

5

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19 January 2020

Arne Nedergaard Kousholt

6

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19 January 2020

Morten Beck Trelle

8

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19 January 2020

Ole N Jensen

9

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19 January 2020

Kristian Helin

10

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19 January 2020

Claus Sorensen

11

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19 January 2020

author name string

Stine Jørgensen

1

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19 January 2020

Morten Eskildsen

2

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19 January 2020

Lisbeth Hansen

4

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19 January 2020

Randi G Syljuåsen

7

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19 January 2020

language of work or name

English

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publication date

1 January 2011

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19 January 2020

published in

Journal of Cell Biology

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19 January 2020

volume

192

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19 January 2020

issue

1

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19 January 2020

page(s)

43-54

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PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression

19 January 2020

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Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase

20 March 2017

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The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure

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PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex

20 March 2017

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CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation

20 March 2017

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A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

20 March 2017

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Modulation of p53 function by SET8-mediated methylation at lysine 382

20 March 2017

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L3MBTL1, a histone-methylation-dependent chromatin lock

20 March 2017

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PCNA, the maestro of the replication fork

20 March 2017

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20 March 2017

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A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

20 March 2017

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PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination

20 March 2017

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The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

20 March 2017

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Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes

20 March 2017

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

20 March 2017

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PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin

20 March 2017

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The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells.

20 March 2017

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CRL4(Cdt2)-mediated destruction of the histone methyltransferase Set8 prevents premature chromatin compaction in S phase

29 September 2017

1 reference

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CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation

29 September 2017

1 reference

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Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice

29 September 2017

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Chromatin structure and the inheritance of epigenetic information

29 September 2017

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DDB2 (damaged-DNA binding protein 2) in nucleotide excision repair and DNA damage response

29 September 2017

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CRL4s: the CUL4-RING E3 ubiquitin ligases

29 September 2017

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The multiple facets of histone H4-lysine 20 methylation

29 September 2017

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Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development

29 September 2017

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Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans

29 September 2017

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The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing

29 September 2017

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ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin

29 September 2017

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Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability

29 September 2017

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Direct interaction between SET8 and proliferating cell nuclear antigen couples H4-K20 methylation with DNA replication

29 September 2017

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Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects

29 September 2017

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The histone methyltransferase SET8 is required for S-phase progression

29 September 2017

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PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase

29 September 2017

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Ubiquitin proteasome system (UPS): what can chromatin do for you?

29 September 2017

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Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

29 September 2017

1 reference

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Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase

29 September 2017

1 reference

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Docking of a specialized PIP Box onto chromatin-bound PCNA creates a degron for the ubiquitin ligase CRL4Cdt2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019552

L2dtl is essential for cell survival and nuclear division in early mouse embryonic development.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201009076

CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201009076

21 January 2018

Identifiers

DOI

10.1083/JCB.201009076

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21220508%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Internet Archive ID

pubmed-PMC3019552

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21220508%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

2 references