Cyclin D1: polymorphism, aberrant splicing and cancer risk (Q28303053)

Europe PubMed Central

title

Cyclin D1: polymorphism, aberrant splicing and cancer risk (English)

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author name string

K E Knudsen

1

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J Alan Diehl

2

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C A Haiman

3

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E S Knudsen

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

4

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language of work or name

English

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publication date

13 March 2006

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published in

Oncogene

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volume

25

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page(s)

1620-8

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issue

11

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cites work

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Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD

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Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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Novel splice variants of cyclin E with altered substrate specificity

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Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

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7 January 2021

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

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Cyclin D1 protein expression and function in human breast cancer

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Molecular pathogenesis and a consequent classification of multiple myeloma

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7 January 2021

Cyclin D1 represses STAT3 activation through a Cdk4-independent mechanism.

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7 January 2021

Association of polymorphisms in the cyclin D1 and XPD genes and susceptibility to cancers of the upper aero-digestive tract

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7 January 2021

Cyclin D1 binding to the androgen receptor (AR) NH2-terminal domain inhibits activation function 2 association and reveals dual roles for AR corepression

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7 January 2021

Emerging roles for E2F: Beyond the G1/S transition and DNA replication

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7 January 2021

Phosphorylation of the retinoblastoma-related protein p130 in growth-arrested cells.

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7 January 2021

Cyclin D1 polymorphism (G870A) and risk for esophageal adenocarcinoma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Increased risk of cervical cancer associated with cyclin D1 gene A870G polymorphism

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7 January 2021

Linking cyclins to transcriptional control.

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7 January 2021

A case-control study of cyclin D1 CCND1 870A-->G polymorphism and bladder cancer.

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7 January 2021

The influence of cyclin D1 (CCND1) 870A>G polymorphism and CCND1-thymidylate synthase (TS) gene-gene interaction on the outcome of childhood acute lymphoblastic leukaemia

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7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

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Prognostic significance of cyclin D1 gene (CCND1) polymorphism in epithelial ovarian cancer.

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7 January 2021

Cycling to cancer with cyclin D1

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A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase

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7 January 2021

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

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7 January 2021

Cyclin proteolysis as a retinoid cancer prevention mechanism

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7 January 2021

Stabilization of cyclin D1 mRNA via the phosphatidylinositol 3-kinase pathway in MCF-7 human breast cancer cells.

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7 January 2021

The activities of cyclin D1 that drive tumorigenesis

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7 January 2021

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract

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7 January 2021

Cyclin D1 genotype and expression in sporadic hemangioblastomas.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

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7 January 2021

Induced expression of human CCND1 alternative transcripts in mouse Cyl-1 knockout fibroblasts highlights functional differences

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7 January 2021

Association of cyclin D1 polymorphism with increased susceptibility to oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 polymorphism and expression in patients with squamous cell carcinoma of the head and neck

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

GG genotype of cyclin D1 G870A polymorphism is associated with increased risk and advanced colorectal cancer in patients in Singapore.

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7 January 2021

Cyclin D1 (PRAD1) alternative transcript b: full-length cDNA cloning and expression in breast cancers

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7 January 2021

Cyclin D1/PRAD1/BCL-1 alternative transcript [B] protein product in B-lymphoid malignancies with t(11;14)(q13;q32) translocation

1 reference

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7 January 2021

Absence of cyclin D1/PRAD1 point mutations in human breast cancers and parathyroid adenomas and identification of a new cyclin D1 gene polymorphism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 gene polymorphism and susceptibility to childhood acute lymphoblastic leukemia in a Chinese population.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

A novel approach to temporary stenting: degradable cardiovascular stents produced from corrodible metal-results 6-18 months after implantation into New Zealand white rabbits

1 reference

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7 January 2021

Gene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Polymorphism within the cyclin D1 gene is associated with an increased risk of carcinoma in situ in patients with superficial bladder cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 G870A polymorphism and squamous cell carcinoma of the uterine cervix in Korean women.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Differential inactivation of CDKN2 and Rb protein in non-small-cell and small-cell lung cancer cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 polymorphism and increased risk of colorectal cancer at young age

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

The 870G>A polymorphism of the cyclin D1 gene is not associated with breast cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Regulation of exit from quiescence by p27 and cyclin D1-CDK4.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Regulation of the functional interaction between cyclin D1 and the estrogen receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Association of the cyclin D1 A870G polymorphism with advanced colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Inhibition of Smad antiproliferative function by CDK phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

D-type cyclin-dependent kinase activity in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 protein expression and gene polymorphism in colorectal cancer. Aberdeen Colorectal Initiative

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Identification of G1 kinase activity for cdk6, a novel cyclin D partner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Control of pRB phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 expression is regulated by the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 gene polymorphism as a risk factor for squamous cell carcinoma of the upper aerodigestive system in non-alcoholics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

CCND1 polymorphism and age of onset of hepatoblastoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1: mechanism and consequence of androgen receptor co-repressor activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 is an early target in hepatocyte proliferation induced by thyroid hormone (T3).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Tumor-specific proteolytic processing of cyclin E generates hyperactive lower-molecular-weight forms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 gene polymorphism and susceptibility to lung cancer in a Chinese population.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Estrogen induction of the cyclin D1 promoter: involvement of a cAMP response-like element

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Polymorphisms in DNA repair and metabolic genes in bladder cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

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7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

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7 January 2021

The RB and p53 pathways in cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 (CCND1) genotype is associated with tumour grade in sporadic pituitary adenomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Increased risk of prostate cancer associated with AA genotype of cyclin D1 gene A870G polymorphism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 gene polymorphism is associated with an increased risk of urinary bladder cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit β-globin gene

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Growth factor regulation of cyclin D1 mRNA expression through protein synthesis-dependent and -independent mechanisms

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 genotype in areca-associated oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Association of the cyclin D1 gene G870A polymorphism with susceptibility to sporadic renal cell carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Association of cyclin D1 (G870A) polymorphism with susceptibility to esophageal and gastric cardiac carcinoma in a northern Chinese population.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Polymorphisms in cyclin D1 gene and hepatocellular carcinoma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Amplification and overexpression of cyclin D1 in human hepatocellular carcinoma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Use of pyrosequencing to detect clinically relevant polymorphisms of genes in basal cell carcinoma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Cyclin D1 polymorphism and risk for squamous cell carcinoma of the head and neck: a case-control study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209371

7 January 2021

Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209371

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2769083

1017363890

0 references

2769083

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference