The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles (Q28303245)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15660127%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles (English)

1 reference

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7 January 2020

5

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7 January 2020

7

Louise N Johnson

1 reference

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7 January 2020

author name string

Reiko Honda

1

1 reference

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7 January 2020

Edward D Lowe

2

1 reference

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7 January 2020

Elena Dubinina

3

1 reference

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7 January 2020

Vicky Skamnaki

4

1 reference

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7 January 2020

Nick R Brown

6

1 reference

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7 January 2020

language of work or name

English

0 references

publication date

20 January 2005

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7 January 2020

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7 January 2020

volume

24

1 reference

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7 January 2020

issue

3

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7 January 2020

page(s)

452-463

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Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT

7 January 2020

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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The CCP4 suite: programs for protein crystallography

20 March 2017

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Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

20 March 2017

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20 March 2017

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Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

20 March 2017

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Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A

20 March 2017

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hCDC4 gene mutations in endometrial cancer

20 March 2017

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Distinct roles for cyclins E and A during DNA replication complex assembly and activation

20 March 2017

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Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

20 March 2017

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Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2

20 March 2017

1 reference

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The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases

20 March 2017

1 reference

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Integration of macromolecular diffraction data

20 March 2017

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CDK inhibitors: positive and negative regulators of G1-phase progression

20 March 2017

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Cyclin E in human cancers.

20 March 2017

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Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity

20 March 2017

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Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins

20 March 2017

1 reference

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Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

20 March 2017

1 reference

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Chromosome association of minichromosome maintenance proteins in Drosophila endoreplication cycles

20 March 2017

1 reference

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Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E

20 March 2017

1 reference

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Structural basis of cyclin-dependent kinase activation by phosphorylation

20 March 2017

1 reference

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Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

20 March 2017

1 reference

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Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1

20 March 2017

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The crystal structure of cyclin A

20 March 2017

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20 March 2017

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Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

21 January 2018

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Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast

20 March 2017

1 reference

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Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

20 March 2017

1 reference

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A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry

20 March 2017

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Cyclin E ablation in the mouse

20 March 2017

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Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle

20 March 2017

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Identification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma protein

20 March 2017

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Crystal structure of cyclin-dependent kinase 2

20 March 2017

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Deregulation of cyclin E in human cells interferes with prereplication complex assembly

7 April 2017

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29 September 2017

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Inactivation of hCDC4 can cause chromosomal instability

29 September 2017

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Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells

29 September 2017

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Driving the cell cycle to cancer.

29 September 2017

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Identification of the nuclear localization signal in Xenopus cyclin E and analysis of its role in replication and mitosis

29 September 2017

1 reference

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Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm

29 September 2017

1 reference

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Analysis of Cdc6 function in the assembly of mammalian prereplication complexes

29 September 2017

1 reference

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Tumor-specific proteolytic processing of cyclin E generates hyperactive lower-molecular-weight forms

29 September 2017

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On the concentrations of cyclins and cyclin-dependent kinases in extracts of cultured human cells.

29 September 2017

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Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

29 September 2017

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Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.

29 September 2017

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The oncogenic activity of cyclin E is not confined to Cdk2 activation alone but relies on several other, distinct functions of the protein

29 September 2017

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Deregulated cyclin E induces chromosome instability

2 June 2018

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Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

2 June 2018

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Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase

2 June 2018

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Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.

2 June 2018

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Proliferation of cancer cells despite CDK2 inhibition.

21 January 2018

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Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/15660127

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Adenosine cyclic 3',5'-monophosphate dependent protein kinase: kinetic mechanism for the bovine skeletal muscle catalytic subunit

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15660127

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7600554

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15660127%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15660127%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference