Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging (Q28305337)

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Language	Label	Description	Also known as
English	Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging	scientific article

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scholarly article

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Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging (English)

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plexiform neurofibroma

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based on heuristic

inferred from title

Timothy P Cripe

10

object named as

Timothy P Cripe

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author name string

Jianqiang Wu

1

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Eva Dombi

2

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Edwin Jousma

3

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R Scott Dunn

4

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Diana Lindquist

5

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Beverly M Schnell

6

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Mi-Ok Kim

7

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Aerang Kim

8

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Brigitte C Widemann

9

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Nancy Ratner

11

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language of work or name

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publication date

February 2012

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Pediatric Blood & Cancer

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58

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2

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173-80

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describes a project that uses

magnetic resonance imaging

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based on heuristic

inferred from title

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

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20 March 2017

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

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20 March 2017

Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow

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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

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7 April 2017

Malignant peripheral nerve sheath tumour (MPNST): the clinical implications of cellular signalling pathways

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29 September 2017

How does the Schwann cell lineage form tumors in NF1?

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Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors

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29 September 2017

Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells

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29 September 2017

Perinatal epidermal growth factor receptor blockade prevents peripheral nerve disruption in a mouse model reminiscent of benign world health organization grade I neurofibroma

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The NF1 tumor suppressor critically regulates TSC2 and mTOR.

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BAY 43-9006: preclinical data

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GTPase activating proteins: critical regulators of intracellular signaling

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29 September 2017

Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts

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29 September 2017

Hyperactive Ras as a therapeutic target in neurofibromatosis type 1.

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29 September 2017

Statistical analysis of in vivo tumor growth experiments

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29 September 2017

Neurofibromatosis type 1

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

Automated detection and volume measurement of plexiform neurofibromas in neurofibromatosis 1 using magnetic resonance imaging

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

NF1 plexiform neurofibroma growth rate by volumetric MRI: relationship to age and body weight.

1 reference

https://api.crossref.org/works/10.1002%2FPBC.23015

21 January 2018

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

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21 January 2018

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

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Physiologically based pharmacokinetic (PBPK) modeling of everolimus (RAD001) in rats involving non-linear tissue uptake.

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21 January 2018

Sorafenib induces growth suppression in mouse models of gastrointestinal stromal tumor

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21 January 2018

Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver

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21 January 2018

Liquid chromatography-tandem mass spectrometric assay for sorafenib and sorafenib-glucuronide in mouse plasma and liver homogenate and identification of the glucuronide metabolite

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21 January 2018

Drug discovery: inhibitors that activate

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21 January 2018

An extensive study on isosorbide-5-mononitrate acid adducts for quantification in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry and its application to bioequivalence sample analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21319287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibromatosis 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21319287

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/PBC.23015

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