The ubiquitin-proteasome system (Q28305844)

ubiquitin-proteasome system

Europe PubMed Central

title

The ubiquitin-proteasome system (English)

0 references

main subject

0 references

author name string

Dipankar Nandi

1

0 references

Pankaj Tahiliani

2

0 references

Anujith Kumar

3

0 references

Dilip Chandu

Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection

4

0 references

language of work or name

English

0 references

publication date

March 2006

0 references

published in

Journal of Biosciences

0 references

volume

31

0 references

issue

1

0 references

page(s)

137-55

0 references

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF02705243

Immune defects in 28-kDa proteasome activator gamma-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02705243

The regulatory particle of the Saccharomyces cerevisiae proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02705243

Simultaneous binding of PA28 and PA700 activators to 20 S proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02705243

Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02705243

The proteasome and MHC class I antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02705243

The COP9 signalosome (CSN): an evolutionary conserved proteolysis regulator in eukaryotic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02705243

Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02705243

The 26S proteasome: a molecular machine designed for controlled proteolysis

21 January 2018

1 reference

12 December 2020

Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

1 reference

12 December 2020

An archaebacterial ATPase, homologous to ATPases in the eukaryotic 26 S proteasome, activates protein breakdown by 20 S proteasomes

1 reference

12 December 2020

Identification of proteassemblin, a mammalian homologue of the yeast protein, Ump1p, that is required for normal proteasome assembly

1 reference

12 December 2020

Expression and subcellular localization of mouse 20S proteasome activator complex PA28

1 reference

12 December 2020

The ubiquitin system: from basic mechanisms to the patient bed.

1 reference

12 December 2020

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

1 reference

12 December 2020

Comparative genomics and functional roles of the ATP-dependent proteases Lon and Clp during cytosolic protein degradation.

1 reference

12 December 2020

Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast

1 reference

12 December 2020

Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue

1 reference

12 December 2020

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

12 December 2020

Purification and characterization of a protein inhibitor of the 20S proteasome (macropain)

1 reference

12 December 2020

Proteasome β-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function

1 reference

12 December 2020

Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome).

1 reference

12 December 2020

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

1 reference

12 December 2020

IFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient response

1 reference

12 December 2020

Critical elements in proteasome assembly

1 reference

12 December 2020

Proteasome from Thermoplasma acidophilum: a threonine protease

1 reference

12 December 2020

Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands

1 reference

12 December 2020

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

1 reference

12 December 2020

Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.

1 reference

12 December 2020

Novel propeptide function in 20 S proteasome assembly influences beta subunit composition

1 reference

12 December 2020

Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors

1 reference

12 December 2020

Role of substrate in reversible activation of proteasomes (multi-protease complexes) by sodium dodecyl sulfate

1 reference

12 December 2020

Deubiquitinating enzymes as cellular regulators

1 reference

12 December 2020

Dynamics of proteasome distribution in living cells

1 reference

12 December 2020

Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes

1 reference

12 December 2020

Aggresomes: a cellular response to misfolded proteins

1 reference

12 December 2020

Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division

1 reference

12 December 2020

H-2-linked low-molecular weight polypeptide antigens assemble into an unusual macromolecular complex

1 reference

12 December 2020

The structure of the mammalian 20S proteasome at 2.75 A resolution

1 reference

12 December 2020

Recycling the Cell Cycle

1 reference

12 December 2020

Towering science: an ounce of creativity is worth a ton of impact

1 reference

12 December 2020

N-terminal ubiquitination: more protein substrates join in.

1 reference

12 December 2020

Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases

1 reference

12 December 2020

Endoproteolytic activity of the proteasome

1 reference

12 December 2020

The multicatalytic proteinase (prosome) is ubiquitous from eukaryotes to archaebacteria

1 reference

12 December 2020

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

12 December 2020

Identification of the active amino acid residue of the polypeptide of ATP-dependent protein breakdown

1 reference

12 December 2020

Potential for proteasome inhibition in the treatment of cancer

1 reference

12 December 2020

Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown

1 reference

12 December 2020

Potential immunocompetence of proteolytic fragments produced by proteasomes before evolution of the vertebrate immune system

1 reference

12 December 2020

PA28, an activator of the 20 S proteasome, is inactivated by proteolytic modification at its carboxyl terminus.

1 reference

12 December 2020

240-kDa proteasome inhibitor (CF-2) is identical to delta-aminolevulinic acid dehydratase

1 reference

12 December 2020

PAN, the proteasome-activating nucleotidase from archaebacteria, is a protein-unfolding molecular chaperone

1 reference

12 December 2020

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

1 reference

12 December 2020

Themes and variations on ubiquitylation

1 reference

12 December 2020

Growth retardation in mice lacking the proteasome activator PA28gamma

1 reference

12 December 2020

The proteasome activator 11 S REG or PA28: chimeras implicate carboxyl-terminal sequences in oligomerization and proteasome binding but not in the activation of specific proteasome catalytic subunits

1 reference

12 December 2020

Proteasome sequences in eubacteria

1 reference

12 December 2020

Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex

1 reference

12 December 2020

Evidence that pituitary cation-sensitive neutral endopeptidase is a multicatalytic protease complex

1 reference

12 December 2020

Inhibition of proteasome activity induces concerted expression of proteasome genes and de novo formation of Mammalian proteasomes

1 reference

12 December 2020

Protein regulation by monoubiquitin

1 reference

12 December 2020

PI31 is a modulator of proteasome formation and antigen processing

1 reference

12 December 2020

Proteasome function is dispensable under normal but not under heat shock conditions in Thermoplasma acidophilum

1 reference

12 December 2020

20S proteasome biogenesis

1 reference

12 December 2020

PA200, a nuclear proteasome activator involved in DNA repair

1 reference

12 December 2020

Multiple forms of the 20 S multicatalytic and the 26 S ubiquitin/ATP-dependent proteases from rabbit reticulocyte lysate

1 reference

12 December 2020

Caspase-dependent inactivation of proteasome function during programmed cell death in Drosophila and man.

1 reference

12 December 2020

For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection

1 reference

12 December 2020

Human immunodeficiency virus‐1 Tat protein interacts with distinct proteasomal α and β subunits

1 reference

12 December 2020

The proteasome activator 11 S regulator or PA28. Contribution By both alpha and beta subunits to proteasome activation

1 reference

12 December 2020

Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide

1 reference

12 December 2020

Molecular clearance of ataxin-3 is regulated by a mammalian E4

1 reference

12 December 2020

Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution

1 reference

12 December 2020

Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits

1 reference

12 December 2020

Dynamic association of proteasomal machinery with the centrosome

1 reference

12 December 2020

Identification and characterization of a mammalian protein interacting with 20S proteasome precursors

1 reference

12 December 2020

Lysosomal cysteine proteases: facts and opportunities

1 reference

12 December 2020

Structure of the proteasome activator REGalpha (PA28alpha)

1 reference

12 December 2020

Identification of an activation region in the proteasome activator REGalpha

1 reference

12 December 2020

Characterisation of the newly identified human Ump1 homologue POMP and analysis of LMP7(beta 5i) incorporation into 20 S proteasomes

1 reference

12 December 2020

Provirus integration into a gene encoding a ubiquitin-conjugating enzyme results in a placental defect and embryonic lethality

1 reference

12 December 2020

UBE3A/E6-AP mutations cause Angelman syndrome

1 reference

12 December 2020

ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation

1 reference

12 December 2020

Proteasomes and their kin: proteases in the machine age

1 reference

12 December 2020

Structure of 20S proteasome from yeast at 2.4 A resolution

1 reference

12 December 2020

A high molecular weight protease in the cytosol of rat liver. I. Purification, enzymological properties, and tissue distribution

1 reference

12 December 2020

Delivery of ubiquitinated substrates to protein-unfolding machines

1 reference

12 December 2020

Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

1 reference

12 December 2020

Proteasome inhibition as a novel therapeutic target in human cancer.

1 reference

12 December 2020

The comparative proteomics of ubiquitination in mouse

1 reference

12 December 2020

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

1 reference

12 December 2020

The proteasome inhibitor PI31 competes with PA28 for binding to 20S proteasomes.

1 reference

12 December 2020

The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.

1 reference

12 December 2020

Multiubiquitylation by E4 enzymes: 'one size' doesn't fit all.

1 reference

12 December 2020

Loss of calpain 3 proteolytic activity leads to muscular dystrophy and to apoptosis-associated IkappaBalpha/nuclear factor kappaB pathway perturbation in mice.

1 reference

12 December 2020

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

12 December 2020

The SCF ubiquitin ligase: insights into a molecular machine

1 reference

12 December 2020

Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes

1 reference

12 December 2020

A cryptic protease couples deubiquitination and degradation by the proteasome

1 reference

12 December 2020

The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study

1 reference

12 December 2020

Schizosaccharomyces pombe Int6 and Ras homologs regulate cell division and mitotic fidelity via the proteasome

1 reference

12 December 2020

Proline- and arginine-rich peptides constitute a novel class of allosteric inhibitors of proteasome activity

1 reference

12 December 2020

Immunochemical analysis of the turnover of ubiquitin-protein conjugates in intact cells. Relationship to the breakdown of abnormal proteins

1 reference

12 December 2020

The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing

1 reference

12 December 2020

Ubiquitin-lysozyme conjugates. Identification and characterization of an ATP-dependent protease from rabbit reticulocyte lysates

1 reference

12 December 2020

Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability

1 reference

12 December 2020

Multiple associated proteins regulate proteasome structure and function

1 reference

12 December 2020

Altered peptidase and viral-specific T cell response in LMP2 mutant mice.

1 reference

12 December 2020

Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly.

1 reference

12 December 2020

Activity and regulation of the centrosome-associated proteasome

1 reference

12 December 2020

Mechanisms underlying ubiquitination

1 reference

12 December 2020

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

1 reference

12 December 2020

Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach

1 reference

12 December 2020

20 S proteasomes are assembled via distinct precursor complexes. Processing of LMP2 and LMP7 proproteins takes place in 13-16 S preproteasome complexes

1 reference

12 December 2020

Degradation of CFTR by the ubiquitin-proteasome pathway

1 reference

12 December 2020

Caspase activation inhibits proteasome function during apoptosis

1 reference

12 December 2020

A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes

1 reference

12 December 2020

Beta 2 subunit propeptides influence cooperative proteasome assembly

1 reference

12 December 2020

Dissociation and reconstitution of the Thermoplasma proteasome

1 reference

12 December 2020

CHIP: a link between the chaperone and proteasome systems

1 reference

12 December 2020

Localization of the 26S proteasome during mitosis and meiosis in fission yeast

1 reference

12 December 2020

MHC class I expression in mice lacking the proteasome subunit LMP-7

1 reference

12 December 2020

Why does threonine, and not serine, function as the active site nucleophile in proteasomes?

1 reference

12 December 2020

Eukaryotic 20S proteasome catalytic subunit propeptides prevent active site inactivation by N-terminal acetylation and promote particle assembly

1 reference

12 December 2020

Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death

1 reference

12 December 2020

Genes required for mycobacterial growth defined by high density mutagenesis

1 reference

12 December 2020

Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly

1 reference

12 December 2020

Substrate specificity of the human proteasome

1 reference

12 December 2020

The protein substrate binding site of the ubiquitin-protein ligase system.

1 reference

12 December 2020

Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits

1 reference

12 December 2020

Degradation of proteasomes by lysosomes in rat liver.

1 reference

12 December 2020

Intracellular localization of proteasomes

1 reference

12 December 2020

Ubiquitin system: JAMMing in the name of the lid.

1 reference

12 December 2020

Structural basis for the activation of 20S proteasomes by 11S regulators

1 reference

12 December 2020

Plasticity in eucaryotic 20S proteasome ring assembly revealed by a subunit deletion in yeast

1 reference

12 December 2020

A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes

1 reference

12 December 2020

Regulated protein degradation

1 reference

12 December 2020

Resolution of the ATP-dependent proteolytic system from reticulocytes: a component that interacts with ATP

1 reference

12 December 2020

Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85

1 reference

12 December 2020

Import of human and Thermoplasma 20S proteasomes into nuclei of HeLa cells requires functional NLS sequences

1 reference

12 December 2020

cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome

1 reference

12 December 2020

Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2.

1 reference

12 December 2020

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis

1 reference

12 December 2020

Immunoproteasome assembly and antigen presentation in mice lacking both PA28alpha and PA28beta.

1 reference

12 December 2020

A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes

1 reference

12 December 2020

Rad23 links DNA repair to the ubiquitin/proteasome pathway

1 reference

12 December 2020

Inactivation of the 20S proteasome in Mycobacterium smegmatis

1 reference

12 December 2020

The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation

1 reference

12 December 2020

The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide

1 reference

12 December 2020

How do endogenous proteins become peptides and reach the endoplasmic reticulum.

1 reference

12 December 2020

The prosome: an ubiquitous morphologically distinct RNP particle associated with repressed mRNPs and containing specific ScRNA and a characteristic set of proteins

1 reference

12 December 2020

Recycling the cell cycle: cyclins revisited

1 reference

12 December 2020