p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition (Q28306282)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24448410%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24448410%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

Senthil K Radhakrishnan

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24448410%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Willem den Besten

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24448410%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Raymond J Deshaies

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24448410%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

language of work or name

English

0 references

publication date

21 January 2014

1 reference

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5 March 2020

1 reference

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5 March 2020

volume

3

1 reference

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5 March 2020

page(s)

e01856

1 reference

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Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

5 March 2020

cites work

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Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice

20 March 2017

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Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase

20 March 2017

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Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration

20 March 2017

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Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

20 March 2017

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Proteasomal degradation is transcriptionally controlled by TCF11 via an ERAD-dependent feedback loop

20 March 2017

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Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells

20 March 2017

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20 March 2017

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Role of Nrf1 in antioxidant response element-mediated gene expression and beyond

20 March 2017

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Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function

20 March 2017

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20 March 2017

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Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

20 March 2017

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Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

20 March 2017

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RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit

20 March 2017

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ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

20 March 2017

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Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.

20 March 2017

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Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3

20 March 2017

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Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs

20 March 2017

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

20 March 2017

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Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site

20 March 2017

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Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

20 March 2017

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OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

20 March 2017

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Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

20 March 2017

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Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

7 April 2017

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Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein

7 April 2017

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Combined inhibition of p97 and the proteasome causes lethal disruption of the secretory apparatus in multiple myeloma cells

7 April 2017

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Perturbations to the ubiquitin conjugate proteome in yeast δubx mutants identify Ubx2 as a regulator of membrane lipid composition

29 September 2017

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The membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Cytoplasmic localization of the ORF2 protein of hepatitis E virus is dependent on its ability to undergo retrotranslocation from the endoplasmic reticulum

29 September 2017

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Retrotranslocation of the chaperone calreticulin from the endoplasmic reticulum lumen to the cytosol

29 September 2017

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The NHB1 (N-terminal homology box 1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its asparagine-glycosylation.

29 September 2017

1 reference

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Isolation of cholesterol-requiring mutant Chinese hamster ovary cells with defects in cleavage of sterol regulatory element-binding proteins at site 1.

2 June 2018

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A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum

2 June 2018

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Crossref

https://api.crossref.org/works/10.7554%2FELIFE.01856

RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.7554%2FELIFE.01856

Identification of topological determinants in the N-terminal domain of transcription factor Nrf1 that control its orientation in the endoplasmic reticulum membrane

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.7554%2FELIFE.01856

Alkylsulfanyl-1,2,4-triazoles, a new class of allosteric valosine containing protein inhibitors. Synthesis and structure-activity relationships

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24448410

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.7554/ELIFE.01856

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24448410%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24448410%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24448410%20AND%20SRC:MED&resulttype=core&format=json