HCT 116 (Q28334584)

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cell line

HCT-116
HCT.116
HCT_116
HCT116
HCT116wt
CoCL2

Language	Label	Description	Also known as
English	HCT 116	cell line	HCT-116 HCT.116 HCT_116 HCT116 HCT116wt CoCL2

Statements

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Cellosaurus release 44

10 January 2023

cancer cell line

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Cellosaurus release 44

10 January 2023

autologous cell line

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10 January 2023

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10 January 2023

described by source

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

1 reference

Cellosaurus release 44

10 January 2023

Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines

1 reference

Cellosaurus release 44

10 January 2023

Selective modifications of cellular proteins in intratumoral subpopulations of human colonic carcinoma cells.

1 reference

Cellosaurus release 44

10 January 2023

Heterogeneity of human colon carcinoma

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Cellosaurus release 44

10 January 2023

Heterogeneity of malignant cells from a human colonic carcinoma.

1 reference

Cellosaurus release 44

10 January 2023

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

1 reference

Cellosaurus release 44

10 January 2023

Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines.

1 reference

Cellosaurus release 44

10 January 2023

BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.

1 reference

Cellosaurus release 44

10 January 2023

Beta-catenin mutations in cell lines established from human colorectal cancers

1 reference

Cellosaurus release 44

10 January 2023

Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.

1 reference

Cellosaurus release 44

10 January 2023

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

1 reference

Cellosaurus release 44

10 January 2023

Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.

1 reference

Cellosaurus release 44

10 January 2023

Systematic variation in gene expression patterns in human cancer cell lines

1 reference

Cellosaurus release 44

10 January 2023

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"

1 reference

Cellosaurus release 44

10 January 2023

Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement.

1 reference

Cellosaurus release 44

10 January 2023

Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.

1 reference

Cellosaurus release 44

10 January 2023

Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures

1 reference

Cellosaurus release 44

10 January 2023

Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.

1 reference

Cellosaurus release 44

10 January 2023

Assembly of microarrays for genome-wide measurement of DNA copy number

1 reference

Cellosaurus release 44

10 January 2023

Mutations of the BRAF gene in human cancer

1 reference

Cellosaurus release 44

10 January 2023

Spectral karyotype analysis of colon cancer cell lines of the tumor suppressor and mutator pathway.

1 reference

Cellosaurus release 44

10 January 2023

Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines

1 reference

Cellosaurus release 44

10 January 2023

Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues

1 reference

Cellosaurus release 44

10 January 2023

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

1 reference

Cellosaurus release 44

10 January 2023

High resolution array-CGH analysis of single cells

1 reference

Cellosaurus release 44

10 January 2023

Colon carcinoma cells harboring PIK3CA mutations display resistance to growth factor deprivation induced apoptosis.

1 reference

Cellosaurus release 44

10 January 2023

Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells

1 reference

Cellosaurus release 44

10 January 2023

Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38.

1 reference

Cellosaurus release 44

10 January 2023

DNA fingerprinting of the NCI-60 cell line panel

1 reference

Cellosaurus release 44

10 January 2023

Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines

1 reference

Cellosaurus release 44

10 January 2023

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers

1 reference

Cellosaurus release 44

10 January 2023

Genomic and biological characterization of exon 4 KRAS mutations in human cancer

1 reference

Cellosaurus release 44

10 January 2023

5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency

1 reference

Cellosaurus release 44

10 January 2023

Therapeutic reactivation of mutant p53 protein by quinazoline derivatives

1 reference

Cellosaurus release 44

10 January 2023

JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs

1 reference

Cellosaurus release 44

10 January 2023

Identification of cancer cell-line origins using fluorescence image-based phenomic screening

1 reference

Cellosaurus release 44

10 January 2023

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

1 reference

Cellosaurus release 44

10 January 2023

Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

1 reference

Cellosaurus release 44

10 January 2023

Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines

1 reference

Cellosaurus release 44

10 January 2023

A novel approach for characterizing microsatellite instability in cancer cells

1 reference

Cellosaurus release 44

10 January 2023

The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology

1 reference

Cellosaurus release 44

10 January 2023

Global proteome analysis of the NCI-60 cell line panel

1 reference

Cellosaurus release 44

10 January 2023

Epigenetic and genetic features of 24 colon cancer cell lines

1 reference

Cellosaurus release 44

10 January 2023

The metabolic demands of cancer cells are coupled to their size and protein synthesis rates

1 reference

Cellosaurus release 44

10 January 2023

High resolution copy number variation data in the NCI-60 cancer cell lines from whole genome microarrays accessible through CellMiner

1 reference

Cellosaurus release 44

10 January 2023

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer

1 reference

Cellosaurus release 44

10 January 2023

A comprehensive transcriptional portrait of human cancer cell lines

1 reference

Cellosaurus release 44

10 January 2023

Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

1 reference

Cellosaurus release 44

10 January 2023

Feasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines.

1 reference

Cellosaurus release 44

10 January 2023

The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets

1 reference

Cellosaurus release 44

10 January 2023

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

1 reference

Cellosaurus release 44

10 January 2023

Metabolic signatures differentiate ovarian from colon cancer cell lines

1 reference

Cellosaurus release 44

10 January 2023

Global metabolite profiling of human colorectal cancer xenografts in mice using HPLC-MS/MS.

1 reference

Cellosaurus release 44

10 January 2023

N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression.

1 reference

Cellosaurus release 44

10 January 2023

Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR

1 reference

Cellosaurus release 44

10 January 2023

A landscape of pharmacogenomic interactions in cancer.

1 reference

Cellosaurus release 44

10 January 2023

A map of mobile DNA insertions in the NCI-60 human cancer cell panel.

1 reference

Cellosaurus release 44

10 January 2023

A novel RNA sequencing data analysis method for cell line authentication

1 reference

Cellosaurus release 44

10 January 2023

Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

1 reference

Cellosaurus release 44

10 January 2023

Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies

1 reference

Cellosaurus release 44

10 January 2023

Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells.

1 reference

Cellosaurus release 44

10 January 2023

Pharmacoproteomic characterisation of human colon and rectal cancer.

1 reference

Cellosaurus release 44

10 January 2023

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay

1 reference

Cellosaurus release 44

10 January 2023

HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer

1 reference

Cellosaurus release 44

10 January 2023

CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma

1 reference

Cellosaurus release 44

10 January 2023

Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53

1 reference

Cellosaurus release 44

10 January 2023

Mutations truncating the EP300 acetylase in human cancers

1 reference

Cellosaurus release 44

10 January 2023

Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers.

1 reference

Cellosaurus release 44

10 January 2023

HLA class I and II genotype of the NCI-60 cell lines

1 reference

Cellosaurus release 44

10 January 2023

p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target

1 reference

Cellosaurus release 44

10 January 2023

Signatures of mutation and selection in the cancer genome

1 reference

Cellosaurus release 44

10 January 2023

Acquired irinotecan resistance is accompanied by stable modifications of cell cycle dynamics independent of MSI status.

1 reference

Cellosaurus release 44

10 January 2023

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines

1 reference

Cellosaurus release 44

10 January 2023

An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes

1 reference

Cellosaurus release 44

10 January 2023

Differential Effector Engagement by Oncogenic KRAS.

1 reference

Cellosaurus release 44

10 January 2023

An Interactive Resource to Probe Genetic Diversity and Estimated Ancestry in Cancer Cell Lines

1 reference

Cellosaurus release 44

10 January 2023

Next-generation characterization of the Cancer Cell Line Encyclopedia

1 reference

Cellosaurus release 44

10 January 2023

Quantitative Proteomics of the Cancer Cell Line Encyclopedia.

1 reference

Cellosaurus release 44

10 January 2023

Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer

1 reference

Cellosaurus release 44

10 January 2023

Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

1 reference

Cellosaurus release 44

10 January 2023

In vitro characterization of spheres derived from colorectal cancer cell lines.

1 reference

Cellosaurus release 44

10 January 2023

Comparison of Different Colorectal Cancer With Liver Metastases Models Using Six Colorectal Cancer Cell Lines

1 reference

Cellosaurus release 44

10 January 2023

Mutations and altered expression of p16INK4 in human cancer.

1 reference

Cellosaurus release 44

10 January 2023

APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.

1 reference

Cellosaurus release 44

10 January 2023

Single-molecule optical genome mapping of a human HapMap and a colorectal cancer cell line.

1 reference

Cellosaurus release 44

10 January 2023

Isolation and Characterization of Two Novel Colorectal Cancer Cell Lines, Containing a Subpopulation with Potential Stem-Like Properties: Treatment Options by MYC/NMYC Inhibition

1 reference

Cellosaurus release 44

10 January 2023

Variation in the extent of microsatellite instability in human cell lines with defects in different mismatch repair genes

1 reference

Cellosaurus release 44

10 January 2023

established from medical condition

colon carcinoma

1 reference

Cellosaurus release 44

10 January 2023

derived from organism type

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Cellosaurus release 44

10 January 2023

http://purl.obolibrary.org/obo/BTO_0001109

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10 January 2023

http://purl.obolibrary.org/obo/EFO_0002824

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Cellosaurus release 44

10 January 2023

http://purl.obolibrary.org/obo/CLO_0003665

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Cellosaurus release 44

10 January 2023

Commons category

HCT116 cells

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Identifiers

MeSH descriptor ID

subject named as

HCT116 Cells

1 reference

Cellosaurus release 44

10 January 2023

A11.251.210.190.380

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A11.251.860.180.380

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Cell Line Ontology ID

1 reference

Cellosaurus release 44

10 January 2023

1 reference

Cellosaurus release 44

10 January 2023

Google Knowledge Graph ID

0 references

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(3 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:HCT116 cells

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