Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes (Q28343931)

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English	Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes	scientific article

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scholarly article

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Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes (English)

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author name string

J G Mabley

1

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W L Suarez-Pinzon

2

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G Haskó

3

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A L Salzman

4

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A Rabinovitch

5

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E Kun

6

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C Szabó

7

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language of work or name

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publication date

July 2001

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British Journal of Pharmacology

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133

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6

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909-19

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Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

20 March 2017

STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

20 March 2017

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

20 March 2017

Studies of streptozotocin-induced insulitis and diabetes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

20 March 2017

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

7 April 2017

Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Intracellular ATP, a switch in the decision between apoptosis and necrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Protection from nicotinamide inhibition of interleukin-1 beta-induced RIN cell nitric oxide formation is associated with induction of MnSOD enzyme activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Effects of cytokines and nitric oxide donors on insulin secretion, cyclic GMP and DNA damage: relation to nitric oxide production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Nicotinamide inhibits IRF-1 mRNA induction and prevents IL-1 beta-induced nitric oxide synthase expression in pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Poly(ADP-ribose) in the cellular response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Streptozotocin-induced pancreatic insulitis in mice. Morphologic and physiologic studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Complete protection from low-dose streptozotocin-induced diabetes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

29 September 2017

Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

2 June 2018

Higher plants possess two structurally different poly(ADP-ribose) polymerases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

2 June 2018

Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

2 June 2018

Endogenous nitric oxide induced by interleukin-1 beta in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

2 June 2018

Interrelationship of changes in islet nicotine adeninedinucleotide, insulin secretion, and cell viability induced by interleukin-1 beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

2 June 2018

Metabolism and beta-cell function of rat pancreatic islets exposed to human interleukin-1 beta in the presence of a high glucose concentration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

2 June 2018

Nicotinamide partially reverses the interleukin-1 beta inhibition of glucose-induced insulin release in pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

2 June 2018

Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

27 November 2018

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

27 November 2018

Poly(ADP-ribose)polymerase activation determines strain sensitivity to streptozotocin-induced beta cell death in inbred mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

27 November 2018

Cytokines activate the nuclear factor kappa B (NF-kappa B) and induce nitric oxide production in human pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572858

27 November 2018

Nicotinamide prevents interleukin-1 effects on accumulated insulin release and nitric oxide production in rat islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical evidence for nitric oxide formation from streptozotocin in isolated pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta effects on cyclic GMP and cyclic AMP in cultured rat islets of Langerhans-arginine-dependence and relationship to insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic effects of cytokines on rat islets: evidence for involvement of free radicals and lipid peroxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of streptozotocin- and alloxan-induced damage in rat B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase, a potential target for drugs: Cellular regulatory role of the polymer and the polymerase protein mediated by catalytic and macromolecular colligative actions (Review)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide protects human beta cells against chemically-induced necrosis, but not against cytokine-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide, nitric oxide, peroxynitrite and cytokine combinations all cause functional impairment and morphological changes in rat islets of Langerhans and insulin secreting cell lines, but dictate cell death by different mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin secretion, DNA damage, and apoptosis in human and rat islets of Langerhans following exposure to nitric oxide, peroxynitrite, and cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cytokine production during development of autoimmune diabetes induced with multiple low doses of streptozotocin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection by 3-aminobenzamide and nicotinamide against streptozotocin-induced beta-cell toxicity in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, against streptozotocin-induced diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell apoptosis is responsible for the development of IDDM in the multiple low-dose streptozotocin model

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: identification of iNOS- expressing cells and relationships to cytokines expressed in the islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide synthesis and the effect of aminoguanidine and NG-monomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates. Lack of correlation with nitric oxide-releasing or O6-alkylating ability

1 reference

https://pubmed.ncbi.nlm.nih.gov/11454665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0704156

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

release_mcnoylqz2jhlbgl34ad2zvhhmi

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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