Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis (Q28344080)

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English	Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis	scientific article

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scholarly article

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Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis (English)

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author name string

Adam S Paszkowski

1

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Bettina Rau

2

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Jens M Mayer

3

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Peter Möller

4

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Hans G Beger

5

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language of work or name

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publication date

January 2002

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Annals of Surgery

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235

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68-76

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1

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Protein measurement with the Folin phenol reagent

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20 March 2017

Structure and mechanism of interleukin-1 beta converting enzyme

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20 March 2017

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

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20 March 2017

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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20 March 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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29 September 2017

Inflammatory mediators in human acute pancreatitis: clinical and pathophysiological implications

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29 September 2017

Bacterial infection and extent of necrosis are determinants of organ failure in patients with acute necrotizing pancreatitis

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29 September 2017

Diagnosis, objective assessment of severity, and management of acute pancreatitis. Santorini consensus conference.

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29 September 2017

Treatment of sepsis: past and future avenues

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29 September 2017

Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing.

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29 September 2017

Identification of a monocyte specific pre-interleukin 1 beta convertase activity

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29 September 2017

Acute pancreatitis and cytokines: "second attack" by septic complication leads to organ failure

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2 June 2018

The physiologic basis for anticytokine clinical trials in the treatment of sepsis

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2 June 2018

The role of cytokines in the pathogenesis of acute pancreatitis

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2 June 2018

Natural course of acute pancreatitis

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2 June 2018

MedCalc: a new computer program for medical statistics.

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2 June 2018

Proinflammatory cytokine release by peripheral blood mononuclear cells from patients with acute pancreatitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1422397

2 June 2018

Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

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2 June 2018

Differential effects of caspase-1/interleukin-1beta-converting enzyme on acinar cell necrosis and apoptosis in severe acute experimental pancreatitis

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27 November 2018

Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia.

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27 November 2018

Timing of tumor necrosis factor antagonism is critical in determining outcome in murine lethal acute pancreatitis

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27 November 2018

Decreased mortality of severe acute pancreatitis after proximal cytokine blockade

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27 November 2018

Interleukin-1 receptor antagonist decreases severity of experimental acute pancreatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1422397

27 November 2018

Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-TNFalpha therapy improves survival and ameliorates the pathophysiologic sequelae in acute pancreatitis in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrapancreatic interleukin-1beta gene expression by specific leukocyte populations during acute pancreatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ICE inhibitor YVADcmk is a potent therapeutic agent against in vivo liver apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic lymphocyte activation modulates the severity of diet-induced acute pancreatitis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased monocyte cytokine production in association with systemic complications in acute pancreatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of polymorphonuclear leukocytes and oxygen-derived free radicals in experimental acute pancreatitis: mediators of local destruction and activators of inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiologic role of oxygen free radicals in acute pancreatitis: initiating event or mediator of tissue damage?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical relevance of caspase-1 activated cytokines in acute pancreatitis: high correlation of serum interleukin-18 with pancreatic necrosis and systemic complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacterial contamination of pancreatic necrosis. A prospective clinical study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amelioration of the physiologic and biochemical changes of acute pancreatitis using an anti-TNF-alpha polyclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severity and mortality of experimental pancreatitis are dependent on interleukin-1 converting enzyme (ICE)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene targeting demonstrates additive detrimental effects of interleukin 1 and tumor necrosis factor during pancreatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The physiologic consequences of macrophage pacification during severe acute pancreatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 receptor antagonist modifies the changes in vital organs induced by acute necrotizing pancreatitis in a rat experimental model

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active interleukin-1 receptor required for maximal progression of acute pancreatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta converting enzyme inhibition blocks progression of type II collagen-induced arthritis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/11753044

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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