HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use (Q28344746)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11782552%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use (English)

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5 December 2019

1

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5 December 2019

author name string

Shawn E Kuhmann

2

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5 December 2019

Julie M Strizki

3

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5 December 2019

Elizabeth Maxwell

4

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5 December 2019

Tom Ketas

5

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5 December 2019

Tom Morgan

6

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5 December 2019

Pavel Pugach

7

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5 December 2019

Serena Xu

8

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5 December 2019

Lisa Wojcik

9

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5 December 2019

Jayaram Tagat

10

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5 December 2019

Anandan Palani

11

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5 December 2019

Sherry Shapiro

12

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5 December 2019

John W Clader

13

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5 December 2019

Stuart McCombie

14

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5 December 2019

Gregory R Reyes

15

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5 December 2019

Bahige M Baroudy

16

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5 December 2019

John P Moore

17

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5 December 2019

language of work or name

English

0 references

publication date

1 January 2002

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

5 December 2019

published in

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5 December 2019

volume

99

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5 December 2019

issue

1

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5 December 2019

page(s)

395-400

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SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo

5 December 2019

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Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

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7 April 2017

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7 April 2017

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7 April 2017

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Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1

29 September 2017

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The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity

29 September 2017

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In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline

29 September 2017

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Involvement of both the V2 and V3 regions of the CCR5-tropic human immunodeficiency virus type 1 envelope in reduced sensitivity to macrophage inflammatory protein 1alpha

29 September 2017

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Expanded tropism of primary human immunodeficiency virus type 1 R5 strains to CD4(+) T-cell lines determined by the capacity to exploit low concentrations of CCR5.

29 September 2017

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Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5

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Highly potent RANTES analogues either prevent CCR5-using human immunodeficiency virus type 1 infection in vivo or rapidly select for CXCR4-using variants.

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Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV-1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage.

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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21 January 2018

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21 January 2018

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21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/11782552

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.012519099

1 reference

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5 December 2019

0 references

1 reference

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5 December 2019

1 reference