The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication (Q28378759)

1

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V Kofler-Mongold

2

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C Leutgeb

3

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V Weber

4

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K Vermeire

5

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S Schacht

6

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J Anné

7

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E de Clercq

8

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R Datema

9

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G Werner

Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction

10

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language of work or name

English

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publication date

February 1996

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published in

Journal of Virology

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volume

70

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issue

2

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page(s)

689-96

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cites work

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Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor

20 March 2017

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Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100

20 March 2017

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Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

20 March 2017

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Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro

20 March 2017

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Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event

20 March 2017

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In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase

20 March 2017

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3'-Azido-3'-deoxythymidine resistance suppressed by a mutation conferring human immunodeficiency virus type 1 resistance to nonnucleoside reverse transcriptase inhibitors

20 March 2017

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

20 March 2017

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Viral dynamics in human immunodeficiency virus type 1 infection

7 April 2017

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Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

7 April 2017

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HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

7 April 2017

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The two zinc fingers in the human immunodeficiency virus type 1 nucleocapsid protein are not functionally equivalent

7 April 2017

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Human immunodeficiency virus type 1 envelope gp120 is cleaved after incubation with recombinant soluble CD4

29 September 2017

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Zinc- and sequence-dependent binding to nucleic acids by the N-terminal zinc finger of the HIV-1 nucleocapsid protein: NMR structure of the complex with the Psi-site analog, dACGCC.

29 September 2017

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Role of HIV-1 envelope V3 loop cleavage in cell tropism

29 September 2017

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Neuron-specific restriction of a herpes simplex virus recombinant maps to the UL5 gene

29 September 2017

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trans-dominant interference of type 5 adenovirus E1a mutants in cell transformation

29 September 2017

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Mutational trends in V3 loop protein sequences observed in different genetic lineages of human immunodeficiency virus type 1.

29 September 2017

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Papilloma formation by cottontail rabbit papillomavirus requires E1 and E2 regulatory genes in addition to E6 and E7 transforming genes.

29 September 2017

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Identification and characterization of vlf-1, a baculovirus gene involved in very late gene expression

29 September 2017

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Structural rearrangements in the transmembrane glycoprotein after receptor binding

29 September 2017

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Dextran sulfate blocks antibody binding to the principal neutralizing domain of human immunodeficiency virus type 1 without interfering with gp120-CD4 interactions

29 September 2017

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The CD4-gp120 interaction and AIDS pathogenesis

29 September 2017

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CD4 activation of HIV fusion

29 September 2017

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Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds

29 September 2017

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T cell activation antigen, CD26, as a cofactor for entry of HIV in CD4+ cells

2 June 2018

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Characterization of human immunodeficiency virus type 1 mutants with decreased sensitivity to proteinase inhibitor Ro 31-8959.

2 June 2018

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Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-tetraazamacrocycles that inhibit HIV replication. Effects of macrocyclic ring size and substituents on the aromatic linker

2 June 2018

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HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase

2 June 2018

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The V3 loops of the HIV-1 and HIV-2 surface glycoproteins contain proteolytic cleavage sites: a possible function in viral fusion?

2 June 2018

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The V3 region of the envelope glycoprotein of human immunodeficiency virus type 1 binds sulfated polysaccharides and CD4-derived synthetic peptides

2 June 2018

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Studies on the role of the V3 loop in human immunodeficiency virus type 1 envelope glycoprotein function

2 June 2018

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Investigations into the mechanism by which sulfated polysaccharides inhibit HIV infection in vitro

2 June 2018

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Local and global structural properties of the HIV-MN V3 loop

2 June 2018

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12 December 2020

CD4-derived peptide and sulfated polysaccharides have similar mechanisms of anti-HIV activity based on electrostatic interactions with positively charged gp120 fragments

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12 December 2020

Mechanism of HIV-1 Entry into CD4+ T Cells

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12 December 2020

Issues in combination antiretroviral therapy: a review

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12 December 2020