Molecular biomarkers for breast cancer prognosis: coexpression of c-erbB-2 and p53 (Q28363615)

2

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D R Crowe

3

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M G Conner

4

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H L Weiss

5

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M T Sellers

6

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H Krontiras

7

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M M Urist

8

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K I Bland

p53, the cellular gatekeeper for growth and division

9

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language of work or name

English

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publication date

May 2001

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published in

Annals of Surgery

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volume

233

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issue

5

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page(s)

630-8

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cites work

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Mutations in p53 are frequent in the preneoplastic stage of mouse mammary tumor development.

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Immunohistochemical studies on c-erbB-2 oncoprotein expression in paraffin embedded tissues in invasive and non-invasive human breast lesions

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Implications of the p53 tumor-suppressor gene in clinical oncology.

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Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

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An immunohistochemical evaluation of c-erbB-2 expression in human breast carcinoma

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An evaluation of immunoreactivity for c-erbB-2 protein as a marker of poor short-term prognosis in breast cancer

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The long term prognostic significance of c-erbB-2 in primary breast cancer

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Association of overexpression of tumor suppressor protein p53 with rapid cell proliferation and poor prognosis in node-negative breast cancer patients

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Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

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Immunohistochemical detection of c-erbB-2 and p53 in benign breast disease and breast cancer risk

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P-glycoprotein, HER-2/neu, and mutant p53 expression in human gynecologic tumors

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Evidence of cumulative gene losses with progression of premalignant epithelial lesions to carcinoma of the bronchus

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Association of c-erbB-2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer.

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P53 in tumour pathology: can we trust immunocytochemistry?

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p53 protein expression and nuclear DNA content in breast intraductal proliferations

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Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer

27 November 2018

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12 December 2020

Overexpression of p53 and HER-2/neu proteins as prognostic markers in early stage breast cancer

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12 December 2020

Coexpression of HER-2/neu and p53 is associated with a shorter disease-free survival in node-positive breast cancer patients

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12 December 2020

p53 accumulation in benign breast biopsy specimens

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12 December 2020

Breast cancer response to adjuvant chemotherapy in correlation with erbB2 and p53 expression

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12 December 2020

p53 in node-negative breast carcinoma: an immunohistochemical study of epidemiologic risk factors, histologic features, and prognosis

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12 December 2020

[Quantitative study of P53 gene protein expression in the benign disease and cancer of breast]

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12 December 2020

p53 mutations in benign breast tissue

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12 December 2020

C-erbB-2: expression in patients with breast carcinoma in comparison to patients with benign breast diseases

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12 December 2020

No additive impact on patient survival of the double alteration of p53 and c-erbB-2 in breast carcinomas

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12 December 2020

Prognostic significance of the co-expression of p53 and c-erbB-2 proteins in breast cancer

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12 December 2020

Value of c-erbB-2 and p53 oncoprotein co-overexpression in human breast cancer

1 reference

12 December 2020

p53 protein expression, cell proliferation and steroid hormone receptors in ductal and lobular in situ carcinomas of the breast

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12 December 2020

Prognostic and predictive value of c-erbB-2 overexpression in primary breast cancer, alone and in combination with other prognostic markers

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12 December 2020

A prospective study of the significance of gene and chromosome alterations as prognostic indicators of breast cancer patients with lymph node metastases

1 reference

12 December 2020

Prospective studies of p53 and c-erbB-2 expression in relation to clinicopathological parameters of human ductal breast cancer in the second stage of clinical advancement

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12 December 2020

erbB-2, p53, and efficacy of adjuvant therapy in lymph node-positive breast cancer

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12 December 2020

p53 and c-erbB-2 protein expression in breast carcinomas. An immunohistochemical study including correlations with receptor status, proliferation markers, and clinical stage in human breast cancer

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12 December 2020

Models for early chemoprevention trials in breast cancer

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12 December 2020

Oncogenes and male breast carcinoma: c-erbB-2 and p53 coexpression predicts a poor survival

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12 December 2020

A randomized prospective trial of radical (Halsted) mastectomy versus modified radical mastectomy in 311 breast cancer patients

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12 December 2020

Amplification of c-erbB-2 and aggressive human breast tumors?

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12 December 2020

Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer

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12 December 2020

Immunohistochemical studies on oncogene products (c-erbB-2, EGFR, c-myc) and estrogen receptor in benign and malignant breast lesions. With special reference to their prognostic significance in carcinoma

1 reference

12 December 2020

Immunohistochemical evaluation of c-erbB-2 oncogene expression in ductal carcinoma in situ and atypical ductal hyperplasia of the breast

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12 December 2020

Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro

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12 December 2020

Immunohistochemical analysis of p53 and HER-2/neu proteins in human tumors

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12 December 2020