The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (Q28364217)

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English	The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase	scientific article

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7 November 2019

The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (English)

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7 November 2019

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R J Konrad

1

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7 November 2019

I Mikolaenko

2

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7 November 2019

J F Tolar

3

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7 November 2019

K Liu

4

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7 November 2019

J E Kudlow

5

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1 May 2001

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7 November 2019

Biochemical Journal

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7 November 2019

356

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7 November 2019

Pt 1

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7 November 2019

31-41

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7 November 2019

Glucose and streptozotocin stimulate p135 O-glycosylation in pancreatic islets

1 reference

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20 March 2017

Localization of the O-linked N-acetylglucosamine transferase in rat pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

The murine glutamine:fructose-6-phosphate amidotransferase-encoding cDNA sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

The crystal structure of a low-molecular-weight phosphotyrosine protein phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

Localization of O-GlcNAc modification on the serum response transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

Cloning and partial characterization of the mouse glutamine:fructose-6-phosphate amidotransferase (GFAT) gene promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

A subpopulation of estrogen receptors are modified by O-linked N-acetylglucosamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 March 2017

Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Phosphorylation and glycosylation of nucleoporins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Compact cell blocks. Use for body fluids, fine needle aspirations and endometrial brush biopsies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Streptozotocin at low doses induces apoptosis and at high doses causes necrosis in a murine pancreatic beta cell line, INS-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Purification and characterization of an O-GlcNAc selective N-acetyl-beta-D-glucosaminidase from rat spleen cytosol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Streptozotocin interactions with pancreatic beta cells and the induction of insulin-dependent diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Complete protection from low-dose streptozotocin-induced diabetes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Pancreatic Beta Cell Toxicity by Streptozotocin Anomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Effect of l-methyl-l-nitrosourea and streptozotocin on glucose-induced insulin secretion by isolated islets of Langerhans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Studies on Streptozotocin Diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

29 September 2017

Control of epithelial immune-response genes and implications for airway immunity and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

2 June 2018

Nitric oxide causes inactivation of the low molecular weight phosphotyrosine protein phosphatase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

2 June 2018

Diabetogenic effects of N-nitrosomethylurea in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

2 June 2018

Distinct regions of Sp1 modulate DNA binding and transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

2 June 2018

Preferential reduction of insulin production in mouse pancreatic islets maintained in culture after streptozotocin exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

2 June 2018

Glycosylation of nuclear pore protein p62. Reticulocyte lysate catalyzes O-linked N-acetylglucosamine addition in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

2 June 2018

S-nitrosylation regulates apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

20 June 2018

The inactivation mechanism of low molecular weight phosphotyrosine-protein phosphatase by H2O2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

27 November 2018

Nitric oxide generation during cellular metabolization of the diabetogenic N-methyl-N-nitroso-urea streptozotozin contributes to islet cell DNA damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221809

27 November 2018

Use of the monoclonal antibody M30 for detecting HSG cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11336633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A modified method of islet isolation preserves the ability of pancreatic islets to increase protein O-glycosylation in response to glucose and streptozotocin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11336633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on L-glutamine D-fructose 6-phosphate amidotransferase. I. Feedback inhibition by uridine diphosphate-N-acetylglucosamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/11336633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of streptozotocin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11336633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative interactions of streptozotocin and chlorozotocin with DNA of an insulin-secreting cell line (RINr)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11336633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of nitrosourea-induced beta-cell damage. Alterations in DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11336633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characteristics of cultured mouse pancreatic islets following exposure to different streptozotocin concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/11336633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical evidence for nitric oxide formation from streptozotocin in isolated pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/11336633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide protects human beta cells against chemically-induced necrosis, but not against cytokine-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11336633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11336633

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/0264-6021:3560031

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11336633%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11336633%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11336633%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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