Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysis (Q28364231)

1

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C Ozvegy

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E Bakos

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B Sarkadi

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A Váradi

Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

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language of work or name

English

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publication date

15 May 2001

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published in

Biochemical Journal

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volume

356

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issue

Pt 1

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page(s)

71-5

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cites work

1 reference

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Crystal structure of the ATP-binding subunit of an ABC transporter

20 March 2017

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ABC Transporters: From Microorganisms to Man

20 March 2017

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Biochemistry of multidrug resistance mediated by the multidrug transporter

20 March 2017

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Transition-state formation in ATPase-negative mutants of human MDR1 protein

7 April 2017

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An inventory of the human ABC proteins

29 September 2017

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Functional consequences of mutations in the conserved 'signature sequence' of the ATP-binding-cassette protein MalK.

29 September 2017

1 reference

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Subunit interactions in ABC transporters: towards a functional architecture

29 September 2017

1 reference

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The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface.

29 September 2017

1 reference

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Effect of modulators on the ATPase activity and vanadate nucleotide trapping of human P-glycoprotein

29 September 2017

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Characterization of the human multidrug resistance protein containing mutations in the ATP-binding cassette signature region

29 September 2017

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The catalytic cycle of P-glycoprotein

29 September 2017

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Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette (ABC) protein superfamily

29 September 2017

1 reference

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Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase

29 September 2017

1 reference

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P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site

29 September 2017

1 reference

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Regulation by ATP and ADP of CFTR chloride channels that contain mutant nucleotide-binding domains

2 June 2018

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Characterization of the azidopine and vinblastine binding site of P-glycoprotein

2 June 2018

1 reference

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Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis.

2 June 2018

1 reference

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Modulation of ATP and drug binding by monoclonal antibodies against P-glycoprotein

27 November 2018

1 reference

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Both P-glycoprotein Nucleotide-binding Sites Are Catalytically Active

27 November 2018

1 reference

12 December 2020

Inhibition of P-glycoprotein ATPase activity by procedures involving trapping of nucleotide in catalytic sites

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12 December 2020

Inhibition of P-glycoprotein ATPase activity by beryllium fluoride

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12 December 2020

Drug-stimulated nucleotide trapping in the human multidrug transporter MDR1. Cooperation of the nucleotide binding domains

1 reference

12 December 2020