Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir. (Q28369030)

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English	Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir.	scientific article

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5 December 2019

Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir (English)

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5 December 2019

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A K Patick

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M Duran

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Y Cao

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D Shugarts

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M R Keller

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E Mazabel

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M Knowles

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S Chapman

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D R Kuritzkes

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M Markowitz

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1 October 1998

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5 December 2019

Antimicrobial Agents and Chemotherapy

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42

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5 December 2019

2637-2644

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5 December 2019

Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease

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20 March 2017

Activities of the human immunodeficiency virus type 1 (HIV-1) protease inhibitor nelfinavir mesylate in combination with reverse transcriptase and protease inhibitors against acute HIV-1 infection in vitro

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A mutation in human immunodeficiency virus type 1 protease at position 88, located outside the active site, confers resistance to the hydroxyethylurea inhibitor SC-55389A

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Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor

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Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease

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Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors

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Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor

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Characterization of a human immunodeficiency virus type 1 variant with reduced sensitivity to an aminodiol protease inhibitor

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Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor

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In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease

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In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

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A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team

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Structural mechanisms of HIV drug resistance

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In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects.

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29 September 2017

Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors

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Emergence of resistant variants of HIV in vivo during monotherapy with the proteinase inhibitor saquinavir

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Human immunodeficiency virus type 1 protease inhibitors

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Mutational anatomy of an HIV-1 protease variant conferring cross-resistance to protease inhibitors in clinical trials. Compensatory modulations of binding and activity

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A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection

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12 December 2020

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10.1128/AAC.42.10.2637

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5 December 2019

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5 December 2019

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