NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats (Q28388958)

10.1186/S12974-016-0669-5

DOI

12 July 2019

http://api.crossref.org/works?select=update-to&filter=doi:10.1186/S12974-016-0669-5

Brent Small

5

0 references

Paula Bickford

object named as

Paula C Bickford

7

0 references

author name string

Antwoine Flowers

1

0 references

Jea-Young Lee

2

0 references

Sandra Acosta

3

0 references

Charles Hudson

4

0 references

Cyndy D Sanberg

Journal of Neuroinflammation

6

0 references

language of work or name

English

0 references

publication date

17 September 2015

0 references

published in

0 references

volume

12

0 references

issue

1

0 references

page(s)

174

0 references

cites work

Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

20 March 2017

The hallmarks of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Glucocorticoid-dependent hippocampal transcriptome in male rats: pathway-specific alterations with aging

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Role of Nrf2 in oxidative stress and toxicity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Neurogenesis, inflammation and behavior

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Spatial learning depends on both the addition and removal of new hippocampal neurons

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

The Wnt signaling pathway in development and disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Wnt signalling regulates adult hippocampal neurogenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Cleaning up after ICH: the role of Nrf2 in modulating microglia function and hematoma clearance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Hippocampal subregions exhibit both distinct and shared transcriptomic responses to aging and nonneurodegenerative cognitive decline.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Innate immune activation in neurodegenerative disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Neuroinflammation: the role and consequences

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Aging-induced Nrf2-ARE pathway disruption in the subventricular zone drives neurogenic impairment in parkinsonian mice via PI3K-Wnt/β-catenin dysregulation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Mitochondria as a source of reactive oxygen and nitrogen species: from molecular mechanisms to human health

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

The role of dietary polyphenols on adult hippocampal neurogenesis: molecular mechanisms and behavioural effects on depression and anxiety

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

When neurogenesis encounters aging and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

NT-020, a natural therapeutic approach to optimize spatial memory performance and increase neural progenitor cell proliferation and decrease inflammation in the aged rat.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Hippocampal neurogenesis during normal and pathological aging

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Regulation of inflammation and redox signaling by dietary polyphenols

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

The effects of aging on the expression of Wnt pathway genes in mouse tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574066

Aging alters long-term potentiation--related gene networks and impairs synaptic protein synthesis in the rat hippocampus

2 June 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-015-0395-4

Hippocampectomized monkeys can remember one place but not two.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-015-0395-4

Activation of the Wnt signaling pathway: a molecular mechanism for lithium action

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-015-0395-4

Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-015-0395-4

PPARγ regulates the mitochondrial dysfunction in human neural stem cells with tumor necrosis factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-015-0395-4

α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-015-0395-4

DLK1 promotes neurogenesis of human and mouse pluripotent stem cell-derived neural progenitors via modulating Notch and BMP signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-015-0395-4

Age-associated dysregulation of microglial activation is coupled with enhanced blood-brain barrier permeability and pathology in APP/PS1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-015-0395-4

T cell migration into the central nervous system during health and disease: Different molecular keys allow access to different central nervous system compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12974-015-0395-4

Neural stem and progenitor cells in the aged subependyma are activated by the young niche

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26376629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Wnt signaling and stem cell control

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26376629

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S12974-015-0395-4

1 reference

Dimensions Publication ID

1022301704

0 references

1 reference

1 reference

PubMed publication ID

26376629

1 reference