Mitochondrial dysfunction in diabetic cardiomyopathy (Q28390863)

Biochimica et Biophysica Acta

Europe PubMed Central

title

Mitochondrial dysfunction in diabetic cardiomyopathy (English)

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diabetic cardiomyopathy

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Jennifer G Duncan

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language of work or name

English

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publication date

July 2011

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published in

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volume

1813

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page(s)

1351-9

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issue

7

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cites work

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

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4Pi microscopy reveals an impaired three-dimensional mitochondrial network of pancreatic islet beta-cells, an experimental model of type-2 diabetes.

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29 September 2017

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Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening

29 September 2017

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Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.

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Mitochondrial uncoupling: a key contributor to reduced cardiac efficiency in diabetes.

29 September 2017

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29 September 2017

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Cardiolipin metabolism and Barth Syndrome

29 September 2017

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Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity

29 September 2017

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Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

29 September 2017

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Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

29 September 2017

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Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

29 September 2017

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Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3.

29 September 2017

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Insulin and inositol 1,4,5-trisphosphate trigger abnormal cytosolic Ca2+ transients and reveal mitochondrial Ca2+ handling defects in cardiomyocytes of ob/ob mice.

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Fatty acid metabolism is enhanced in type 2 diabetic hearts

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Mitochondrial metabolism of reactive oxygen species.

29 September 2017

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The role of the peroxisome proliferator-activated receptor alpha pathway in pathological remodeling of the diabetic heart.

29 September 2017

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The evolving diabetes burden in the United States

29 September 2017

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Heart failure: the frequent, forgotten, and often fatal complication of diabetes

29 September 2017

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Dynamics of mitochondrial morphology in healthy cells and during apoptosis

29 September 2017

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Protein tyrosine nitration in the mitochondria from diabetic mouse heart. Implications to dysfunctional mitochondria in diabetes

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Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart

29 September 2017

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Glucose and reactive oxygen species

29 September 2017

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Hyperglycemia-induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathway

29 September 2017

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PPAR signaling in the control of cardiac energy metabolism

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29 September 2017

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29 September 2017

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Functional binding of cardiolipin to cytochrome c oxidase

29 September 2017

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Myocardial substrate metabolism: implications for diabetic cardiomyopathy

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Effect of Free Fatty Acids on Myocardial Function and Oxygen Consumption in Intact Dogs

29 September 2017

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29 September 2017

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Accumulation of Myocardial Triglycerides in Ketotic Diabetes: Evidence for Increased Biosynthesis

29 September 2017

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Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha

29 September 2017

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Shotgun lipidomics identifies cardiolipin depletion in diabetic myocardium linking altered substrate utilization with mitochondrial dysfunction

2 June 2018

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2 June 2018

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Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus

2 June 2018

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Regulation of energy substrate metabolism in the diabetic heart

2 June 2018

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Mitochondrial dysfunction accompanies diastolic dysfunction in diabetic rat heart

2 June 2018

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Effect of free fatty acids on myocardial function and metabolism in the ischemic dog heart

2 June 2018

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2 June 2018

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Tissue advanced glycation end products are associated with diastolic function and aerobic exercise capacity in diabetic heart failure patients

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27 November 2018

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27 November 2018

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Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy

27 November 2018

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27 November 2018

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1 reference

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Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncoupling protein levels

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Regulation of Ca2+ signalling and Ca2+-mediated cell death by the transcriptional coactivator PGC-1alpha.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Increased hypercholesterolemia and atherosclerosis in mice lacking both ApoE and leptin receptor

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Inhibition of superoxide generation and associated nitrosative damage is involved in metallothionein prevention of diabetic cardiomyopathy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Rosiglitazone treatment in Zucker diabetic Fatty rats is associated with ameliorated cardiac insulin resistance and protection from ischemia/reperfusion-induced myocardial injury

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Decreased sarcoplasmic reticulum activity and contractility in diabetic db/db mouse heart

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Uncoupling proteins in human heart

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Store-operated Ca2+ entry: dynamic interplay between endoplasmic reticulum, mitochondria and plasma membrane

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Echocardiographic assessment of cardiac function in diabetic db/db and transgenic db/db-hGLUT4 mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated wi

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149859

Activation of nicotinamide adenine dinucleotide phosphate (reduced form) oxidase by advanced glycation end products links oxidative stress to altered retinal vascular endothelial growth factor expression

27 November 2018

1 reference

12 December 2020

Further characterization of mitochondrial contact sites: effect of short-chain alcohols on membrane fluidity and activity

1 reference

12 December 2020

Myocardial cell death in human diabetes

1 reference

12 December 2020

Defective oxidative metabolism of heart mitochondria from genetically diabetic mice

1 reference

12 December 2020

Diabetic cardiomyopathy

1 reference

12 December 2020

Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice

1 reference

12 December 2020

Cardiolipin requirement for electron transfer in complex I and III of the mitochondrial respiratory chain

1 reference

12 December 2020

Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy

1 reference

12 December 2020

10.1016/J.BBAMCR.2011.01.014

Identifiers

DOI

1 reference

release_4g3szl6k4rbp7dgndufgc2i47y

291286

Fatcat ID

0 references

291286

1 reference

1 reference

1 reference