Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture (Q28391219)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25075203%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

title

Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture (English)

1 reference

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11 March 2020

1 reference

1 reference

Uros Rajcevic

1

1 reference

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11 March 2020

Jaco C Knol

2

1 reference

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11 March 2020

Sébastien Bougnaud

4

1 reference

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11 March 2020

Fred Fack

5

1 reference

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11 March 2020

Eirik Sundlisaeter

6

1 reference

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11 March 2020

Karl Søndenaa

7

1 reference

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11 March 2020

Reidar Myklebust

8

1 reference

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11 March 2020

Thang V Pham

9

1 reference

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11 March 2020

Connie R Jiménez

11

1 reference

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11 March 2020

language of work or name

English

0 references

publication date

11 July 2014

1 reference

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11 March 2020

2 references

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11 March 2020

volume

12

1 reference

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11 March 2020

issue

1

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page(s)

39

1 reference

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describes a project that uses

11 March 2020

Cytoscape

object named as

Cytoscape

2 references

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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The roles of PARP1 in gene control and cell differentiation

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Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

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CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors

20 March 2017

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The epithelial-mesenchymal transition generates cells with properties of stem cells

20 March 2017

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Identification of stem cells in small intestine and colon by marker gene Lgr5

20 March 2017

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Phenotypic characterization of human colorectal cancer stem cells

20 March 2017

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PCNA, the maestro of the replication fork

20 March 2017

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Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling

20 March 2017

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

20 March 2017

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Identification and expansion of human colon-cancer-initiating cells

20 March 2017

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Identification of human brain tumour initiating cells

20 March 2017

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A distinct "side population" of cells with high drug efflux capacity in human tumor cells

20 March 2017

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Cancerous stem cells can arise from pediatric brain tumors

20 March 2017

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Identification of a cancer stem cell in human brain tumors

20 March 2017

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The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing

20 March 2017

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20 March 2017

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Identification of 'tissue' transglutaminase binding proteins in neural cells committed to apoptosis

20 March 2017

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20 March 2017

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20 March 2017

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Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

7 April 2017

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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

7 April 2017

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Tumor cell metabolism: cancer's Achilles' heel

7 April 2017

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The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly

7 April 2017

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7 April 2017

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Secreted heat shock protein 90α (HSP90α) induces nuclear factor-κB-mediated TCF12 protein expression to down-regulate E-cadherin and to enhance colorectal cancer cell migration and invasion.

29 September 2017

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In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

29 September 2017

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Proteomics in studying cancer stem cell biology

29 September 2017

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The multicellular tumor spheroid model for high-throughput cancer drug discovery

29 September 2017

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The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers

29 September 2017

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New aspects of the Warburg effect in cancer cell biology

29 September 2017

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29 September 2017

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Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target

29 September 2017

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In vitro production of functional sperm in cultured neonatal mouse testes

29 September 2017

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Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload

29 September 2017

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Heterochromatin protein 1 (HP1) connects the FACT histone chaperone complex to the phosphorylated CTD of RNA polymerase II.

29 September 2017

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Chromatin environment of histone variant H3.3 revealed by quantitative imaging and genome-scale chromatin and DNA immunoprecipitation.

29 September 2017

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29 September 2017

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Workflow comparison for label-free, quantitative secretome proteomics for cancer biomarker discovery: method evaluation, differential analysis, and verification in serum

29 September 2017

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Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness.

29 September 2017

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Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination

29 September 2017

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DeubiKuitylation: a novel DUB enzymatic activity for the DNA repair protein, Ku70.

29 September 2017

1 reference

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PCNA on the crossroad of cancer

29 September 2017

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In-gel digestion of proteins for MALDI-MS fingerprint mapping

29 September 2017

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Mitochondria in cancer cells: what is so special about them?

29 September 2017

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Cancer stem cells--old concepts, new insights.

29 September 2017

1 reference

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A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

29 September 2017

1 reference

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The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases.

29 September 2017

1 reference

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Wnt/beta-catenin signaling in cancer stemness and malignant behavior

29 September 2017

1 reference

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Angiogenesis-independent tumor growth mediated by stem-like cancer cells

29 September 2017

1 reference

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The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia

29 September 2017

1 reference

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Telomeres and telomerase in cancer stem cells.

29 September 2017

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Combined modality therapy of gemcitabine and irradiation on human glioma spheroids derived from cell lines and biopsy tissue.

29 September 2017

1 reference

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Mitogenic influence of human R-spondin1 on the intestinal epithelium

29 September 2017

1 reference

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Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin

29 September 2017

1 reference

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Taking the study of cancer cell survival to a new dimension

29 September 2017

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Chromatofocusing nonporous reversed-phase high-performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry of proteins from human breast cancer whole cell lysates: a novel two-dimensional liquid chromatography/mass spe

29 September 2017

1 reference

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Growth of precultured human glioma specimens in nude rat brain

29 September 2017

1 reference

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Three-dimensional spheroid model in tumor biology

29 September 2017

1 reference

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Human aldehyde dehydrogenase gene family.

29 September 2017

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Growth and cellular characteristics of multicell spheroids.

29 September 2017

1 reference

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Multicellular spheroids. A review on cellular aggregates in cancer research

29 September 2017

1 reference

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The enzymes of detoxication

29 September 2017

1 reference

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Cysteinyl leukotrienes synthesis is involved in aristolochic acid I-induced apoptosis in renal proximal tubular epithelial cells

29 September 2017

1 reference

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Cell and environment interactions in tumor microregions: the multicell spheroid model

2 June 2018

1 reference

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Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens.

2 June 2018

1 reference

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The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114130

Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (cytoxan) (AC) response and resistance

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114130

Poly(ADP-ribose) polymerase-1 is a component of the oncogenic T-cell factor-4/beta-catenin complex.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114130

NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114130

Survival in three dimensions

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114130

Multicellular tumor spheroids from human gliomas maintained in organ culture

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114130

Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan

27 November 2018

1 reference

12 December 2020

Isolation of cancer stem cells from adult glioblastoma multiforme

1 reference

12 December 2020

The new look of colorectal cancer stem cells

1 reference

12 December 2020

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

1 reference

12 December 2020

Tumour fragment spheroids from human non-small-cell lung cancer maintained in organ culture

1 reference

12 December 2020

Identifiers

DOI

10.1186/1477-5956-12-39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25075203%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25075203%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

PubMed publication ID

25075203

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25075203%20AND%20SRC:MED&resulttype=core&format=json