Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110 (Q28391904)

2

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Joseph M Baisden

3

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Scott A Weed

4

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Daniel C Flynn

Molecular and Cellular Biology

5

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language of work or name

English

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publication date

September 2004

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published in

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volume

24

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page(s)

7578-97

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issue

17

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cites work

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Podosomes: adhesion hot-spots of invasive cells

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Protein kinase C induces actin reorganization via a Src- and Rho-dependent pathway

29 September 2017

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The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases

29 September 2017

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29 September 2017

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Protein kinase C as a drug target: implications for drug or diet prevention and treatment of cancer

29 September 2017

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PKC-dependent activation of FAK and src induces tyrosine phosphorylation of Cas and formation of Cas-Crk complexes

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The carboxy terminus of AFAP-110 modulates direct interactions with actin filaments and regulates its ability to alter actin filament integrity and induce lamellipodia formation

29 September 2017

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The SH3 and SH2 domains are capable of directing specificity in protein interactions between the non-receptor tyrosine kinases cSrc and cYes

29 September 2017

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The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphos

29 September 2017

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Monoclonal antibodies directed against AFAP-110 recognize species-specific and conserved epitopes

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Rho and Rab small G proteins coordinately reorganize stress fibers and focal adhesions in MDCK cells

29 September 2017

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Eps8, a tyrosine kinase substrate, is recruited to the cell cortex and dynamic F-actin upon cytoskeleton remodeling

29 September 2017

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Formation of a stable src-AFAP-110 complex through either an amino-terminal or a carboxy-terminal SH2-binding motif

29 September 2017

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Src can regulate carboxy terminal interactions with AFAP-110, which influence self-association, cell localization and actin filament integrity

29 September 2017

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Enhancement of migration by protein kinase Calpha and inhibition of proliferation and cell cycle progression by protein kinase Cdelta in capillary endothelial cells

29 September 2017

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Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate

29 September 2017

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The sites of phosphorylation by protein kinase C and an intact SH2 domain are required for the enhanced response to beta-adrenergic agonists in cells overexpressing c-src

29 September 2017

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Association of type 3 protein kinase C with focal contacts in rat embryo fibroblasts

29 September 2017

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Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

29 September 2017

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Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes

29 September 2017

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Activation of erbB2 and c-src in phorbol ester-treated mouse epidermis: possible role in mouse skin tumor promotion

29 September 2017

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Selective activation of protein kinase C isoforms by v-Src

2 June 2018

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Increased protein kinase C alpha expression in human colonic Caco-2 cells after insertion of human Ha-ras or polyoma virus middle T oncogenes.

2 June 2018

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Protein kinase C phosphorylates pp60src at a novel site.

2 June 2018

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Site-specific increased phosphorylation of pp60v-src after treatment of RSV-transformed cells with a tumor promoter.

2 June 2018

1 reference

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pp60v-src association with the cytoskeleton induces actin reorganization without affecting polymerization status.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=506973

v-Src activates both protein kinase C-dependent and independent signaling pathways in murine fibroblasts

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=506973

Localization of the viral and cellular Src kinases to perinuclear vesicles in fibroblasts

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=506973

Protein kinase C delta induces Src kinase activity via activation of the protein tyrosine phosphatase PTP alpha

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=506973

Conventional protein kinase C mediates phorbol-dibutyrate-induced cytoskeletal remodeling in a7r5 smooth muscle cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=506973

Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=506973

The integrity of the SH3 binding motif of AFAP-110 is required to facilitate tyrosine phosphorylation by, and stable complex formation with, Src

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=506973

Cytoskeletal architecture in mouse lung epithelial cells is regulated by protein-kinase C-alpha and calpain II

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15314167

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential activation of protein kinase C isozymes by phorbol ester and collagen in human skin microvascular endothelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15314167

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.24.17.7578-7597.2004

1 reference

release_m4ylrdkb45advobh6zjcvua27i

699153

Fatcat ID

0 references

699153

1 reference

1 reference

1 reference