Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice (Q28396141)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0110075

negative regulation of ferroptosis

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0110076

Glutathione peroxidase 4

1 reference

GOA release 2020-03-11

author

Frauke Neff

Jose Pedro Friedmann Angeli

16

0 references

Jose Pedro Friedmann Angeli

1

0 references

Nadja Herbach

Nadja Herbach

7

0 references

Rüdiger Wanke

Rüdiger Wanke

18

0 references

Marcus Conrad

Marcus Conrad

29

0 references

Vladimir Tyurin

Vladimir A Tyurin

5

0 references

Devaraj Basavarajappa

Devaraj Basavarajappa

11

0 references

Valerie O'Donnell

Valerie B O'Donnell

26

0 references

Olof Rådmark

12

Olof Rådmark

0 references

Irene Esposito

17

Irene Esposito

0 references

Georg W Bornkamm

22

Georg W Bornkamm

0 references

Yulia Y. Tyurina

4

Yulia Y Tyurina

0 references

Valerian E. Kagan

27

Valerian E Kagan

0 references

author name string

Manuela Schneider

2

0 references

Bettina Proneth

3

0 references

Victoria J Hammond

6

0 references

Michaela Aichler

8

0 references

Axel Walch

9

0 references

Elke Eggenhofer

10

0 references

Sho Kobayashi

13

0 references

Tobias Seibt

14

0 references

Heike Beck

15

0 references

Heidi Förster

19

0 references

Olena Yefremova

20

0 references

Marc Heinrichmeyer

21

0 references

Edward K Geissler

23

0 references

Stephen B Thomas

24

0 references

Brent R Stockwell

25

0 references

Joel A Schick

A mitochondrial pathway for biosynthesis of lipid mediators

28

0 references

language of work or name

English

0 references

publication date

December 2014

0 references

published in

Nature Cell Biology

0 references

volume

16

0 references

issue

12

0 references

page(s)

1180-91

0 references

cites work

1 reference

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19 March 2017

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Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663

19 March 2017

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19 March 2017

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Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

19 March 2017

1 reference

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Sterol carrier protein-2-facilitated intermembrane transfer of cholesterol- and phospholipid-derived hydroperoxides

19 March 2017

1 reference

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Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein

19 March 2017

1 reference

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The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

19 March 2017

1 reference

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Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

19 March 2017

1 reference

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Molecular mechanisms of necroptosis: an ordered cellular explosion

7 April 2017

1 reference

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Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

7 April 2017

1 reference

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Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models

7 April 2017

1 reference

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Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

29 September 2017

1 reference

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Regulation of ferroptotic cancer cell death by GPX4

29 September 2017

1 reference

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The role of iron and reactive oxygen species in cell death

29 September 2017

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A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles

29 September 2017

1 reference

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Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death

29 September 2017

1 reference

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Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

29 September 2017

1 reference

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29 September 2017

Glutathione peroxidases

1 reference

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Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models

29 September 2017

1 reference

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Ferroptosis: an iron-dependent form of nonapoptotic cell death

29 September 2017

1 reference

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Bioactive oxidatively truncated phospholipids in inflammation and apoptosis: formation, targets, and inactivation

29 September 2017

1 reference

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Targeting IAP proteins for therapeutic intervention in cancer

29 September 2017

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The oxidative stress-inducible cystine/glutamate antiporter, system x (c) (-) : cystine supplier and beyond

29 September 2017

1 reference

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12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

29 September 2017

1 reference

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Sterol carrier protein-2 (SCP-2) involvement in cholesterol hydroperoxide cytotoxicity as revealed by SCP-2 inhibitor effects

29 September 2017

1 reference

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Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions

29 September 2017

1 reference

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Mitochondrial glutathione peroxidase 4 disruption causes male infertility

29 September 2017

1 reference

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Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

29 September 2017

1 reference

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29 September 2017

1 reference

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Identification of mosquito sterol carrier protein-2 inhibitors.

29 September 2017

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Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury.

29 September 2017

1 reference

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Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

2 June 2018

1 reference

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2 June 2018

1 reference

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Combined deficiency in glutathione peroxidase 4 and vitamin E causes multiorgan thrombus formation and early death in mice

2 June 2018

1 reference

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Unconventional RORγt+ T cells drive hepatic ischemia reperfusion injury.

27 November 2018

1 reference

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Cysteine mutant of mammalian GPx4 rescues cell death induced by disruption of the wild-type selenoenzyme.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894846

RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

27 November 2018

1 reference

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Diabetic kidney lesions of GIPRdn transgenic mice: podocyte hypertrophy and thickening of the GBM precede glomerular hypertrophy and glomerulosclerosis

27 November 2018

1 reference

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Oxidative lipidomics of gamma-irradiation-induced intestinal injury

27 November 2018

1 reference

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Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4894846

Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrate

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25402683

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25402683

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB3064

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCB3064

1 reference

Dimensions Publication ID

1265021

1015732022

0 references

1265021

1 reference

1 reference

1 reference