AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts (Q28396630)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17885682%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts (English)

1 reference

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7 January 2020

1 reference

1 reference

2

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7 January 2020

author name string

Jing Zhang

1

1 reference

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7 January 2020

Marlene C Artime

3

1 reference

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7 January 2020

Justin M Summy

4

1 reference

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7 January 2020

Ami N Shah

5

1 reference

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7 January 2020

Joshua A Bomser

6

1 reference

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7 January 2020

Andrea Dorfleutner

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17885682%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Daniel C Flynn

8

1 reference

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7 January 2020

Gary E Gallick

9

1 reference

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7 January 2020

language of work or name

English

0 references

publication date

1 October 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17885682%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

7 January 2020

published in

1 reference

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7 January 2020

volume

117

1 reference

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7 January 2020

issue

10

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7 January 2020

page(s)

2962-2973

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beta 1 integrin function in vivo: adhesion, migration and more

7 January 2020

cites work

1 reference

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Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110

19 March 2017

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Src family kinases in tumor progression and metastasis

19 March 2017

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PKC phosphorylation increases the ability of AFAP-110 to cross-link action filaments

19 March 2017

1 reference

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Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility

19 March 2017

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Paxillin interactions

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Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation

19 March 2017

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Protein kinase C-alpha: a novel target for the therapy of androgen-independent prostate cancer? (Review-hypothesis)

19 March 2017

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19 March 2017

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pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

19 March 2017

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The development of androgen-independent prostate cancer

19 March 2017

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AFAP-110 is required for actin stress fiber formation and cell adhesion in MDA-MB-231 breast cancer cells

7 April 2017

1 reference

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Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells

29 September 2017

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Neurotensin stimulates mitogenesis of prostate cancer cells through a novel c-Src/Stat5b pathway

29 September 2017

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Prostate cancer stem cells.

29 September 2017

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Cortactin affects cell migration by regulating intercellular adhesion and cell spreading

29 September 2017

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Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model

29 September 2017

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A tumour stem cell hypothesis for the origins of prostate cancer

29 September 2017

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Clinging to life: cell to matrix adhesion and cell survival

29 September 2017

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Genistein modulates prostate epithelial cell proliferation via estrogen- and extracellular signal-regulated kinase-dependent pathways

29 September 2017

1 reference

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c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK.

29 September 2017

1 reference

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Cortactin overexpression inhibits ligand-induced down-regulation of the epidermal growth factor receptor

29 September 2017

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The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model.

29 September 2017

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HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.

29 September 2017

1 reference

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Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion

29 September 2017

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Analysis of the role of the leucine zipper motif in regulating the ability of AFAP-110 to alter actin filament integrity

29 September 2017

1 reference

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Reduced c-Met expression by an adenovirus expressing a c-Met ribozyme inhibits tumorigenic growth and lymph node metastases of PC3-LN4 prostate tumor cells in an orthotopic nude mouse model

29 September 2017

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Down-regulation of c-Met inhibits growth in the liver of human colorectal carcinoma cells

29 September 2017

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Cyclin D1, EMS1 and 11q13 amplification in breast cancer

29 September 2017

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Amplification and overexpression of the EMS 1 oncogene, a possible prognostic marker, in human hepatocellular carcinoma

29 September 2017

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Integrin-protein kinase C relationships

29 September 2017

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Regulation of protrusive and contractile cell-matrix contacts.

29 September 2017

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The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases

29 September 2017

1 reference

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The actin filament-associated protein AFAP-110 is an adaptor protein that modulates changes in actin filament integrity

29 September 2017

1 reference

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The carboxy terminus of AFAP-110 modulates direct interactions with actin filaments and regulates its ability to alter actin filament integrity and induce lamellipodia formation

29 September 2017

1 reference

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Actin cytoskeleton organization in response to integrin-mediated adhesion

29 September 2017

1 reference

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Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978423

Intermediate Cells in Human Prostate Epithelium Are Enriched in Proliferative Inflammatory Atrophy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978423

Role of the cytoskeleton in adhesion stabilization of human colorectal carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978423

Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978423

Protein kinase C-{alpha} mediates epidermal growth factor receptor transactivation in human prostate cancer cells

2 June 2018

1 reference

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Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells.

27 November 2018

1 reference

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Proliferative heterogeneity in the human prostate: evidence for epithelial stem cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978423

The integrity of the SH3 binding motif of AFAP-110 is required to facilitate tyrosine phosphorylation by, and stable complex formation with, Src

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1978423

EMS1 gene amplification correlates with poor prognosis in squamous cell carcinomas of the head and neck

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17885682

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of protein kinase C isoenzymes in benign hyperplasia and carcinoma of prostate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17885682

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MUC1, MUC2, MUC4, MUC5AC and MUC6 Expression in the Progression of Prostate Cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17885682

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI30710

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17885682%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17885682%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

17885682

2 references