Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia (Q28474531)

1

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Emmanuel P Dassa

2

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Sergio Goncalves

3

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Françoise Auchère

4

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Maria Lönn

5

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Arne Holmgren

Creative Commons Attribution 4.0 International

6

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language of work or name

English

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publication date

2009

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published in

PLOS One

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volume

4

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issue

1

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page(s)

e4253

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copyright license

start time

22 January 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

19 March 2017

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Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes

19 March 2017

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Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin

19 March 2017

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Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

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Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

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Deferiprone targets aconitase: implication for Friedreich's ataxia treatment

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Hydrogen peroxide scavenging rescues frataxin deficiency in a Drosophila model of Friedreich's ataxia

29 September 2017

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Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial

29 September 2017

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How does iron-sulfur cluster coordination regulate the activity of human glutaredoxin 2?

29 September 2017

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The use of antioxidants in Friedreich's ataxia treatment

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Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2

29 September 2017

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The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis

29 September 2017

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29 September 2017

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A cellular model for Friedreich Ataxia reveals small-molecule glutathione peroxidase mimetics as novel treatment strategy

29 September 2017

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2 June 2018

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Production of reactive oxygen species due to metabolic activation of butylated hydroxyanisole

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Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist

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Antioxidants and phase 2 enzymes in macrophages: regulation by Nrf2 signaling and protection against oxidative and electrophilic stress

27 November 2018

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The mtDNA NARP mutation activates the actin-Nrf2 signaling of antioxidant defenses

27 November 2018

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Causative role of oxidative stress in a Drosophila model of Friedreich ataxia.

27 November 2018

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Reduction of Caenorhabditis elegans frataxin increases sensitivity to oxidative stress, reduces lifespan, and causes lethality in a mitochondrial complex II mutant

27 November 2018

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The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice.

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2617762

Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2617762

Friedreich ataxia: the oxidative stress paradox

27 November 2018

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The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast.

27 November 2018

1 reference

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Functional studies of frataxin.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2617762

Actin glutathionylation increases in fibroblasts of patients with Friedreich's ataxia: a potential role in the pathogenesis of the disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2617762

The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2617762

Heart hypertrophy and function are improved by idebenone in Friedreich's ataxia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2617762

Superoxide-induced massive apoptosis in cultured skin fibroblasts harboring the neurogenic ataxia retinitis pigmentosa (NARP) mutation in the ATPase-6 gene of the mitochondrial DNA.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2617762

Oxidative stress and protease dysfunction in the yeast model of Friedreich ataxia

27 November 2018

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12 December 2020

Disabled early recruitment of antioxidant defenses in Friedreich's ataxia

1 reference

12 December 2020

Manganese superoxide dismutase induction by iron is impaired in Friedreich ataxia cells

1 reference

12 December 2020

Mitochondria, from cell death to proliferation

1 reference

12 December 2020

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

12 December 2020

Friedreich's ataxia: a clinical and genetic study of 90 families with an analysis of early diagnostic criteria and intrafamilial clustering of clinical features

1 reference

12 December 2020

Biochemical and molecular investigations in respiratory chain deficiencies

1 reference

12 December 2020

EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage

1 reference

12 December 2020

Quinone analogs prevent enzymes targeted in Friedreich ataxia from iron-induced injury in vitro

1 reference

12 December 2020

Effect of idebenone on cardiomyopathy in Friedreich's ataxia: a preliminary study

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0004253

Identifiers

DOI

1 reference

814096

ADS bibcode

2009PLoSO...4.4253P

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814096

1 reference

1 reference

1 reference