Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA (Q28475481)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20844768%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA (English)

1 reference

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14 February 2020

1 reference

7

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14 February 2020

Donald E Ayer

8

1 reference

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14 February 2020

author name string

Julia Ling-Yu Chen

1

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14 February 2020

Daniel Merl

2

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14 February 2020

Christopher W Peterson

3

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14 February 2020

Jianli Wu

4

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14 February 2020

Patrick Yantyng Liu

5

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14 February 2020

Hanwei Yin

6

1 reference

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14 February 2020

Mike West

9

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14 February 2020

Jen-Tsan Chi

10

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14 February 2020

language of work or name

English

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publication date

2 September 2010

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14 February 2020

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14 February 2020

volume

6

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14 February 2020

issue

9

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14 February 2020

page(s)

e1001093

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Creative Commons Attribution 4.0 International

14 February 2020

copyright license

start time

2 September 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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24 May 2017

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29 September 2017

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Thioredoxin-interacting protein (Txnip) is a feedback regulator of S-nitrosylation

29 September 2017

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Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity.

29 September 2017

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Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells

29 September 2017

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29 September 2017

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29 September 2017

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The genomic analysis of lactic acidosis and acidosis response in human cancers

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

1 reference

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29 September 2017

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29 September 2017

1 reference

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29 September 2017

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TXNIP regulates peripheral glucose metabolism in humans

29 September 2017

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29 September 2017

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Tumor lactate content predicts for response to fractionated irradiation of human squamous cell carcinomas in nude mice.

29 September 2017

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Hypoxia-induced energy stress regulates mRNA translation and cell growth

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

29 September 2017

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Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

29 September 2017

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29 September 2017

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The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

29 September 2017

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29 September 2017

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29 September 2017

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Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells.

29 September 2017

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29 September 2017

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A unique pathway of cardiac myocyte death caused by hypoxia-acidosis.

29 September 2017

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Lactate: mirror and motor of tumor malignancy

29 September 2017

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Tumor microenvironmental physiology and its implications for radiation oncology

29 September 2017

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Tuberous sclerosis complex: from Drosophila to human disease.

29 September 2017

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Loss of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 in human T-cell leukemia virus type I-dependent T-cell transformation: implications for adult T-cell leukemia leukemogenesis

29 September 2017

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Na-H exchange-dependent increase in intracellular pH times G2/M entry and transition

29 September 2017

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Low pH enhances Sp1 DNA binding activity and interaction with TBP.

29 September 2017

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The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

Lactate stimulates fibroblast expression of hyaluronan and CD44: the Warburg effect revisited

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

Intracellular pH regulation in a nonmalignant and a derived malignant human breast cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

The expanding family of eucaryotic Na(+)/H(+) exchangers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

Exposure to hypoxia, glucose starvation and acidosis: effect on invasive capacity of murine tumor cells and correlation with cathepsin (L + B) secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

Focal localization of the NHE-1 isoform of the Na+/H+ antiport: assessment of effects on intracellular pH.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

Metabolic acidosis stimulates muscle protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

Metabolic regulation via intracellular pH

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

Evidence for 5' AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

Role of intracellular pH in proliferation, transformation, and apoptosis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

A microenvironmental model of carcinogenesis.

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001093

HIF activation by pH-dependent nucleolar sequestration of VHL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001093

Lactate modulates gene expression in human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001093

Genome-wide gene expression profiling reveals renal genes regulated during metabolic acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001093

Hepatocellular carcinoma in Txnip-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001093

AMPK activation increases uncoupling protein-3 expression and mitochondrial enzyme activities in rat muscle without fibre type transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001093

The AMP-activated protein kinase activator, 5-aminoimidazole-4-carboxamide-1-b-D-ribonucleoside, regulates lactate production in rat Sertoli cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001093

Regulation of transcription by AMP-activated protein kinase: phosphorylation of p300 blocks its interaction with nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001093

Endogenous hypoxia markers: case not proven!

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001093

Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001093

Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937306

An examination of the effects of hypoxia, acidosis, and glucose starvation on the expression of metastasis-associated genes in murine tumor cells.

27 November 2018

1 reference

12 December 2020

TXNIP Links Redox Circuitry to Glucose Control

1 reference

12 December 2020

Effect of AMPK activation on muscle glucose metabolism in conscious rats

1 reference

12 December 2020

Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells

1 reference

12 December 2020

Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells

1 reference

12 December 2020

Cytoplasmic pH, a key determinant of growth factor-induced DNA synthesis in quiescent fibroblasts

1 reference

12 December 2020

Acidosis-sensing glutamine pump SNAT2 determines amino acid levels and mammalian target of rapamycin signalling to protein synthesis in L6 muscle cells

1 reference

12 December 2020

High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1001093

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20844768%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20844768%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

2 references