Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling (Q28475546)

3

object named as

Emmanuelle Charafe-Jauffret

0 references

Max S Wicha

8

object named as

Max S Wicha

0 references

author name string

Hasan Korkaya

1

0 references

Amanda Paulson

2

0 references

Christophe Ginestier

4

0 references

Marty Brown

5

0 references

Julie Dutcher

6

0 references

Shawn G Clouthier

Creative Commons Attribution 4.0 International

7

0 references

language of work or name

English

0 references

publication date

2 June 2009

0 references

published in

PLOS Biology

0 references

volume

7

0 references

issue

6

0 references

page(s)

e1000121

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copyright license

start time

2 June 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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19 March 2017

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19 March 2017

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Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

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29 September 2017

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PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

29 September 2017

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29 September 2017

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PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients

29 September 2017

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Regulation of the self-renewal ability of tissue stem cells by tumor-related genes

29 September 2017

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Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

29 September 2017

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Selective targeting of cancer stem cells: a new concept in cancer therapeutics

29 September 2017

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CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.

29 September 2017

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Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation

29 September 2017

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29 September 2017

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WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells

29 September 2017

1 reference

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Complete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis

29 September 2017

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29 September 2017

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Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation

29 September 2017

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Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells

29 September 2017

1 reference

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Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.

29 September 2017

1 reference

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29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Inhibition of AKT survival pathway by a small molecule inhibitor in human endometrial cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Wnt proteins in mammary development and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Stem cells in normal breast development and breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Wnt signalling in mammalian development and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Cancer stem cells contribute to cisplatin resistance in Brca1/p53-mediated mouse mammary tumors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Radiation resistance and stem-like cells in brain tumors.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Premalignant and in situ breast disease: biology and clinical implications.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Reduced expression of PTEN correlates with breast cancer progression

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Lipopolysaccharide activates Akt in human alveolar macrophages resulting in nuclear accumulation and transcriptional activity of beta-catenin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683567

Reconstruction of human mammary tissues in a mouse model

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19492080

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phospho Akt mediates multidrug resistance of gastric cancer cells through regulation of P-gp, Bcl-2 and Bax

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19492080

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19492080

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PBIO.1000121

1 reference

1498433

1498433

1 reference

1 reference

1 reference