LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors (Q28475761)

2

object named as

Dyana T Saenz

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author name string

Anne M Meehan

1

0 references

Jose A Garcia-Rivera

4

0 references

Mary Peretz

5

0 references

Manuel Llano

6

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Eric M Poeschla

Creative Commons Attribution 4.0 International

7

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language of work or name

English

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publication date

July 2009

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published in

PLOS Pathogens

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volume

5

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page(s)

e1000522

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issue

7

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copyright license

start time

17 July 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

19 March 2017

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An essential role for LEDGF/p75 in HIV integration

19 March 2017

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A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo

19 March 2017

1 reference

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Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus

19 March 2017

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H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain

19 March 2017

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Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

19 March 2017

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19 March 2017

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Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase

19 March 2017

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Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase

19 March 2017

1 reference

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LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

19 March 2017

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Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes

19 March 2017

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The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo

19 March 2017

1 reference

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LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

19 March 2017

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HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

19 March 2017

1 reference

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The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds

19 March 2017

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Large-scale identification of mammalian proteins localized to nuclear sub-compartments

19 March 2017

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Initial sequencing and analysis of the human genome

19 March 2017

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Dynamic binding of histone H1 to chromatin in living cells

19 March 2017

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Rapid exchange of histone H1.1 on chromatin in living human cells

19 March 2017

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Nucleosomes, linker DNA, and linker histone form a unique structural motif that directs the higher-order folding and compaction of chromatin

19 March 2017

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Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation

19 March 2017

1 reference

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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

19 March 2017

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Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Chromatin tethering of incoming foamy virus by the structural Gag protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Menin critically links MLL proteins with LEDGF on cancer-associated target genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Nucleosome repeat length and linker histone stoichiometry determine chromatin fiber structure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

The life cycle of the metazoan nuclear envelope

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

The lentiviral integrase binding protein LEDGF/p75 and HIV-1 replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Integrase, LEDGF/p75 and HIV replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Mobility and immobility of chromatin in transcription and genome stability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

HIV integration site selection: analysis by massively parallel pyrosequencing reveals association with epigenetic modifications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Disruption of Ledgf/Psip1 results in perinatal mortality and homeotic skeletal transformations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Modulating target site selection during human immunodeficiency virus DNA integration in vitro with an engineered tethering factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Transcriptional co-activator p75 binds and tethers the Myc-interacting protein JPO2 to chromatin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Determinants of histone H1 mobility and chromatin binding in living cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Role of linker histone in chromatin structure and function: H1 stoichiometry and nucleosome repeat length

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Mapping the interaction surface of linker histone H1(0) with the nucleosome of native chromatin in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Variations in the association of papillomavirus E2 proteins with mitotic chromosomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

A role for LEDGF/p75 in targeting HIV DNA integration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

What functions do linker histones provide?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Unintegrated lentivirus DNA persistence and accessibility to expression in nondividing cells: analysis with class I integrase mutants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Metaphase chromosome tethering is necessary for the DNA synthesis and maintenance of oriP plasmids but is insufficient for transcription activation by Epstein-Barr nuclear antigen 1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

The roles of cellular factors in retroviral integration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

HIV integrase, a brief overview from chemistry to therapeutics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Coupling of mitotic chromosome tethering and replication competence in epstein-barr virus-based plasmids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Maintenance of Epstein-Barr virus (EBV) oriP-based episomes requires EBV-encoded nuclear antigen-1 chromosome-binding domains, which can be replaced by high-mobility group-I or histone H1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

CXCR4 is required by a nonprimate lentivirus: heterologous expression of feline immunodeficiency virus in human, rodent, and feline cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Integration of murine leukemia virus DNA depends on mitosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Histories H1 and H5: one or two molecules per nucleosome?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

LEDGF/p75 interacts with divergent lentiviral integrases and modulates their enzymatic activity in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Nuclear reassembly excludes large macromolecules

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706977

Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication

2 June 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000522

Kaposi's sarcoma-associated herpesvirus LANA hitches a ride on the chromosome.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000522

Dynamic interaction of HMGA1a proteins with chromatin.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000522

Nucleocytoplasmic sorting of macromolecules following mitosis: fate of nuclear constituents after inhibition of pore complex function

21 January 2018

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https://pubmed.ncbi.nlm.nih.gov/19609362

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A MENage à Trois in leukemia

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19609362