Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75 (Q28250867)

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11 January 2020

title

Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75 (English)

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11 January 2020

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4

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6

Alan Engelman

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11 January 2020

1

Peter Cherepanov

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11 January 2020

author name string

Zhen-Yu J Sun

series ordinal

2

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11 January 2020

Shaila Rahman

series ordinal

3

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11 January 2020

Gerhard Wagner

series ordinal

5

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language of work or name

English

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publication date

15 May 2005

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Nature Structural & Molecular Biology

11 January 2020

published in

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11 January 2020

volume

12

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issue

6

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11 January 2020

page(s)

526-532

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Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleus

11 January 2020

cites work

1 reference

Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation

21 April 2017

1 reference

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

21 April 2017

1 reference

LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

21 April 2017

1 reference

Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase

21 April 2017

1 reference

Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75

21 April 2017

1 reference

Degradation of HIV-1 integrase by the N-end rule pathway

21 April 2017

1 reference

Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase

21 April 2017

1 reference

The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds

21 April 2017

1 reference

A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery

21 April 2017

1 reference

Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp

21 April 2017

1 reference

RNA recognition via the SAM domain of Smaug

21 April 2017

1 reference

Crystal structure of human eIF3k, the first structure of eIF3 subunits

21 April 2017

1 reference

Transcriptional regulation of the antioxidant protein 2 gene, a thiol-specific antioxidant, by lens epithelium-derived growth factor to protect cells from oxidative stress

21 April 2017

1 reference

Specificity of interaction of INI1/hSNF5 with retroviral integrases and its functional significance

21 April 2017

1 reference

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 April 2017

1 reference

AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

21 April 2017

1 reference

MOLMOL: a program for display and analysis of macromolecular structures

21 April 2017

1 reference

Comparison of ARM and HEAT protein repeats

21 April 2017

1 reference

Anatomy of hot spots in protein interfaces

21 April 2017

1 reference

HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

21 April 2017

1 reference

LEDGF/p75: a novel nuclear autoantigen at the crossroads of cell survival and apoptosis

21 January 2018

1 reference

Genetic control of retrovirus susceptibility in mammalian cells

21 January 2018

1 reference

Human cell proteins and human immunodeficiency virus DNA integration

21 January 2018

1 reference

Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.

21 January 2018

1 reference

High-level expression of active HIV-1 integrase from a synthetic gene in human cells

21 January 2018

1 reference

Intracellular transport of human immunodeficiency virus type 1 integrase

21 January 2018

1 reference

Targeting survival: integration site selection by retroviruses and LTR-retrotransposons

21 January 2018

1 reference

The ups and downs of gene expression and retroviral DNA integration

21 January 2018

1 reference

Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering

21 January 2018

1 reference

Solution structure and heparin interaction of human hepatoma-derived growth factor

21 January 2018

1 reference

Activity of recombinant HIV-1 integrase on mini-HIV DNA.

21 January 2018

1 reference

HIV-1 infection requires a functional integrase NLS.

21 January 2018

1 reference

Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import

21 January 2018

1 reference

Reversion of the lethal phenotype of an HIV-1 integrase mutant virus by overexpression of the same integrase mutant protein.

21 January 2018

1 reference

Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replication

21 January 2018

1 reference

HIV-1-associated uracil DNA glycosylase activity controls dUTP misincorporation in viral DNA and is essential to the HIV-1 life cycle

21 January 2018

1 reference

Functional role of HIV-1 virion-associated uracil DNA glycosylase 2 in the correction of G:U mispairs to G:C pairs.

21 January 2018

1 reference

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location

21 January 2018

1 reference

IBIS--a tool for automated sequential assignment of protein spectra from triple resonance experiments

21 January 2018

1 reference

Multidimensional heteronuclear nuclear magnetic resonance of proteins

21 January 2018

1 reference

NMR spectroscopy: a multifaceted approach to macromolecular structure

21 January 2018

1 reference

Protein backbone angle restraints from searching a database for chemical shift and sequence homology

21 January 2018

1 reference

Support of1H NMR assignments in proteins by biosynthetically directed fractional13C-labeling

21 January 2018

1 reference

t(9;11)(p22;p15) with NUP98-LEDGF fusion gene in pediatric acute myeloid leukemia

21 January 2018

1 reference

The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding

31 March 2020

1 reference

Protein Motifs. 7. The four-helix bundle: what determines a fold?

31 March 2020

1 reference

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

31 March 2020

1 reference

Measuring protein-protein interactions inside living cells using single color fluorescence correlation spectroscopy. Application to human immunodeficiency virus type 1 integrase and LEDGF/p75.

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Antiviral activity of the proteasome on incoming human immunodeficiency virus type 1.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NSMB937

2 references

Consolidated OpenCitations Corpus – April 2017

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11 January 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017