Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice (Q28476642)

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19 January 2020

title

Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice (English)

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19 January 2020

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1

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Carlos M Rodriguez-Ortigosa

19 January 2020

4

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19 January 2020

Jesus M Banales

5

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19 January 2020

Saioa Goñi

7

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19 January 2020

Juan Angel Recio

11

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19 January 2020

Sophie Lotersztajn

12

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19 January 2020

Jesús Prieto

13

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19 January 2020

Carmen Berasain

14

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19 January 2020

Matias Avila

17

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19 January 2020

author name string

Carmen Gil-Puig

2

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19 January 2020

Maite G Fernández-Barrena

3

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19 January 2020

Raquel Urtasun

6

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19 January 2020

Miriam Méndez

8

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19 January 2020

Sara Arcelus

9

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19 January 2020

Nerea Juanarena

10

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19 January 2020

Fernando J Corrales

15

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19 January 2020

Jon Lecanda

16

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19 January 2020

language of work or name

English

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publication date

29 December 2010

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19 January 2020

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19 January 2020

volume

5

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19 January 2020

issue

12

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19 January 2020

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e15690

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Creative Commons Attribution 4.0 International

19 January 2020

copyright license

start time

29 December 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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2 June 2018

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2 June 2018

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27 November 2018

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Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells

27 November 2018

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JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation

27 November 2018

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Deficiency of tenascin-C attenuates liver fibrosis in immune-mediated chronic hepatitis in mice.

27 November 2018

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c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity

27 November 2018

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Methylthioadenosine reverses brain autoimmune disease

27 November 2018

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Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout mice

27 November 2018

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Differential regulation of the JNK/AP-1 pathway by S-adenosylmethionine and methylthioadenosine in primary rat hepatocytes versus HuH7 hepatoma cells.

27 November 2018

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27 November 2018

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27 November 2018

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The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation

27 November 2018

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Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

27 November 2018

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FGF2-induced chromatin remodeling regulates CNTF-mediated gene expression and astrocyte differentiation

27 November 2018

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Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase

27 November 2018

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Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts

27 November 2018

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S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells.

27 November 2018

1 reference

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5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication.

27 November 2018

1 reference

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Mdr2 (Abcb4)-/- mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes

27 November 2018

1 reference

12 December 2020

Secretion of MCP-1/CCL2 by bile duct epithelia induces myofibroblastic transdifferentiation of portal fibroblasts

1 reference

12 December 2020

Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient mice

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12 December 2020

Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C

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12 December 2020

Multiple inflammatory-, tissue remodelling- and fibrosis genes are differentially transcribed in the livers of Abcb4 (-/ - ) mice harbouring chronic cholangitis

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12 December 2020

Expression of cyclins D1, D2 and E correlates with proliferation of rat stellate cells in culture

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12 December 2020

Biological effects of C-type natriuretic peptide in human myofibroblastic hepatic stellate cells

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12 December 2020

10.1371/JOURNAL.PONE.0015690

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21209952%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21209952%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

21209952

1 reference