Portal fibroblasts: Underappreciated mediators of biliary fibrosis (Q37704267)

22 August 2017

1 reference

title

Portal fibroblasts: Underappreciated mediators of biliary fibrosis (English)

1 reference

22 August 2017

Jonathan A Dranoff

1

1 reference

PMCID

2850946

22 August 2017

Rebecca G Wells

series ordinal

2

1 reference

PMCID

2850946

22 August 2017

language of work or name

English

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publication date

1 April 2010

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22 August 2017

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22 August 2017

51

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22 August 2017

1438-1444

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22 August 2017

4

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Immunohistochemical study of the phenotypic change of the mesenchymal cells during portal tract maturation in normal and fibrous (ductal plate malformation) fetal liver

22 August 2017

1 reference

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CCR2 promotes hepatic fibrosis in mice

23 August 2017

1 reference

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Foxl1 is a marker of bipotential hepatic progenitor cells in mice

23 August 2017

1 reference

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Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development

23 August 2017

1 reference

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p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver

23 August 2017

1 reference

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IL-6 downregulates transcription of NTPDase2 via specific promoter elements

23 August 2017

1 reference

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Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

An immunohistochemical method for identifying fibroblasts in formalin-fixed, paraffin-embedded tissue

23 August 2017

1 reference

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Thy-1 is expressed in hepatic myofibroblasts and not oval cells in stem cell-mediated liver regeneration.

23 August 2017

1 reference

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Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling.

23 August 2017

1 reference

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Hepatic fibrosis and cirrhosis: the (myo)fibroblastic cell subpopulations involved

23 August 2017

1 reference

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Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization

23 August 2017

1 reference

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Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Ectonucleotidase NTPDase2 is selectively down-regulated in biliary cirrhosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Portal tract fibrogenesis in the liver

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

The ecto-nucleoside triphosphate diphosphohydrolase NTPDase2/CD39L1 is expressed in a novel functional compartment within the liver

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Mesenchymal cells in the liver--one cell type or two?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Beauty is in the eye of the beholder: emerging concepts and pitfalls in hepatic stellate cell research

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Rat liver myofibroblasts and hepatic stellate cells differ in CD95-mediated apoptosis and response to TNF-alpha

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Myofibroblasts and mechano-regulation of connective tissue remodelling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

The pathobiology of biliary epithelia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Peribiliary myofibroblasts in biliary type liver fibrosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Proliferating bile duct epithelial cells are a major source of connective tissue growth factor in rat biliary fibrosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: correlation with monocyte infiltration.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Hepatic lipocytes: the principal collagen-producing cells of normal rat liver

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Transforming growth factors beta 1 and beta 2 are differentially expressed in fibrotic liver disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Fibrillin-1 expression in normal and fibrotic rat liver and in cultured hepatic fibroblastic cells: modulation by mechanical stress and role in cell adhesion.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Hepatic fibrosis. Correlation of biochemical and morphologic investigations

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Cellular retinol-binding protein-1 expression and modulation during in vivo and in vitro myofibroblastic differentiation of rat hepatic stellate cells and portal fibroblasts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Studies on the fine structure of proliferated bile ductules. II. Changes of the ductule-connective tissue envelope relationship

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Tropoelastin expression is up-regulated during activation of hepatic stellate cells and in the livers of CCl(4)-cirrhotic rats

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Extracellular matrix deposition, lysyl oxidase expression, and myofibroblastic differentiation during the initial stages of cholestatic fibrosis in the rat.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Thy-1 is expressed in myofibroblasts but not found in hepatic stellate cells following liver injury

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

The hedgehog pathway regulates remodelling responses to biliary obstruction in rats.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Prominent contribution of portal mesenchymal cells to liver fibrosis in ischemic and obstructive cholestatic injuries.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Fibrosis correlates with a ductular reaction in hepatitis C: roles of impaired replication, progenitor cells and steatosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Autocrine release of TGF-beta by portal fibroblasts regulates cell growth.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

The myofibroblastic conversion of peribiliary fibrogenic cells distinct from hepatic stellate cells is stimulated by platelet-derived growth factor during liver fibrogenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Tumor necrosis factor-alpha and transforming growth factor-beta reflect severity of liver damage in primary biliary cirrhosis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

PDGF-mediated chemoattraction of hepatic stellate cells by bile duct segments in cholestatic liver injury

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

The role of TGFbeta1 in initiating hepatic stellate cell activation in vivo

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

The myofibroblast: a quarter century after its discovery.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850946

Ectonucleotidase NTPDase2 Is Selectively Down-Regulated in Biliary Cirrhosis

1 September 2018

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Crossref

https://api.crossref.org/works/10.1002%2FHEP.23405

Connective tissue growth factor in human liver cirrhosis

21 January 2018

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12 December 2020

Secretion of MCP-1/CCL2 by bile duct epithelia induces myofibroblastic transdifferentiation of portal fibroblasts

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12 December 2020

Portal fibroblasts and myofibroblasts in baboons after long-term alcohol consumption

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12 December 2020

Phenotypic change in portal fibroblasts in biliary fibrosis

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12 December 2020

Expression and cellular localization of fibrillin-1 in normal and pathological human liver

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12 December 2020

Isolation of primary rat liver fibroblasts

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12 December 2020

Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells: evidence for matrix-dependent deactivation of stellate cells

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12 December 2020

Isolation and culture of hepatic lipocytes, Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan

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12 December 2020

HEPATIC MESENCHYMAL CELL REACTION IN LIVER DISEASE

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12 December 2020

Transforming growth factor-beta and substrate stiffness regulate portal fibroblast activation in culture

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12 December 2020

The correlation between portal myofibroblasts and development of intrahepatic bile ducts and arterial branches in human liver

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12 December 2020

Localization of liver myofibroblasts and hepatic stellate cells in normal and diseased rat livers: distinct roles of (myo-)fibroblast subpopulations in hepatic tissue repair

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12 December 2020

Reversal of activation of human myofibroblast-like cells by culture on a basement membrane-like substrate

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12 December 2020

Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat

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12 December 2020

Fat-storing cells of the rat liver. Their isolation and purification

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12 December 2020

The ductular cell reaction of rat liver in extrahepatic cholestasis. II. The proliferation of connective tissue

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12 December 2020

Increased expression of interleukin-6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: in situ and culture study

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12 December 2020

Identifiers

DOI

10.1002/HEP.23405

1 reference

22 August 2017

1 reference

22 August 2017

1 reference

PMCID

2850946