Necdin, a negative growth regulator, is a novel STAT3 target gene down-regulated in human cancer (Q28477663)

1

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Steven Eschrich

2

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Gregory Bloom

3

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Yihong Ma

4

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Susan Minton

5

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Richard Jove

6

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W Douglas Cress

Creative Commons Attribution 4.0 International

7

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language of work or name

English

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publication date

2011

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published in

PLOS One

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volume

6

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issue

10

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page(s)

e24923

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copyright license

start time

27 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells

29 September 2017

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Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

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29 September 2017

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29 September 2017

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Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

29 September 2017

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Interleukin-6 induces prostate cancer cell growth accompanied by activation of stat3 signaling pathway .

29 September 2017

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IL-6 up-regulates mcl-1 in human myeloma cells through JAK / STAT rather than ras / MAP kinase pathway

29 September 2017

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

29 September 2017

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Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

29 September 2017

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STAT3 mediates the survival signal in oncogenic ras-transfected intestinal epithelial cells

29 September 2017

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Regulation of STAT-dependent pathways by growth factors and cytokines.

29 September 2017

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Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203112

Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells

29 September 2017

1 reference

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A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203112

Identification of novel direct Stat3 target genes for control of growth and differentiation

29 September 2017

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Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity.

2 June 2018

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Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203112

Arrest of Cell Growth by Necdin, a Nuclear-Protein Expressed in Postmitotic Neurons

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203112

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203112

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

2 June 2018

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Activated signal transducers and activators of transcription 3 signaling induces CD46 expression and protects human cancer cells from complement-dependent cytotoxicity

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024923

Necdin: a multi functional protein with potential tumor suppressor role?

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024923

Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases.

21 January 2018

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Transformation fingerprint: induced STAT3-C, v-Src and Ha-Ras cause small initial changes but similar established profiles in mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024923

Full oncogenic activities of v-Src are mediated by multiple signaling pathways. Ras as an essential mediator for cell survival.

21 January 2018

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Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203112

Small changes in expression affect predisposition to tumorigenesis

27 November 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024923

Stat3 mediates interleukin-6 [correction of interelukin-6] inhibition of human endothelial nitric-oxide synthase expression

21 January 2018

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12 December 2020

Inhibition of constitutively activated Stat3 signaling pathway suppresses growth of prostate cancer cells

1 reference

12 December 2020

Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas

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12 December 2020

Interleukin-6 as a paracrine and autocrine growth factor in human prostatic carcinoma cells in vitro

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12 December 2020

Circulating levels of interleukin-6 in patients with hormone refractory prostate cancer

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12 December 2020

10.1371/JOURNAL.PONE.0024923

Identifiers

DOI

1 reference

ADS bibcode

2011PLoSO...624923H

0 references

1 reference

1 reference

PubMed publication ID

22046235

1 reference