Antifungal drug discovery: something old and something new (Q28483546)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22969422%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

review article

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title

Antifungal drug discovery: something old and something new (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22969422%20AND%20SRC:MED&resulttype=core&format=json

biomedical investigative technique

13 February 2020

main subject

drug discovery

0 references

1 reference

19 September 2019

2

1 reference

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13 February 2020

author name string

Arielle Butts

series ordinal

1

1 reference

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13 February 2020

language of work or name

English

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publication date

6 September 2012

1 reference

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13 February 2020

4 references

20 June 2019

22 June 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22969422%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

8

1 reference

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13 February 2020

issue

9

1 reference

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13 February 2020

page(s)

e1002870

1 reference

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Creative Commons Attribution 4.0 International

13 February 2020

copyright license

3 references

20 June 2019

22 June 2019

Identification and characterization of antifungal compounds using a Saccharomyces cerevisiae reporter bioassay

19 September 2019

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Discovery of a small-molecule inhibitor of {beta}-1,6-glucan synthesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Antifungal chemical compounds identified using a C. elegans pathogenicity assay

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Inhibiting GPI anchor biosynthesis in fungi stresses the endoplasmic reticulum and enhances immunogenicity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

The antidepressant sertraline provides a promising therapeutic option for neurotropic cryptococcal infections

29 September 2017

1 reference

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Discovery of a novel class of orally active antifungal beta-1,3-D-glucan synthase inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

In vitro activity of E1210, a novel antifungal, against clinically important yeasts and molds

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Efficacy of oral E1210, a new broad-spectrum antifungal with a novel mechanism of action, in murine models of candidiasis, aspergillosis, and fusariosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Confronting the challenges of natural product-based antifungal discovery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Identification, in vitro activity and mode of action of phosphoinositide-dependent-1 kinase inhibitors as antifungal molecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Antifungal activity of tamoxifen: in vitro and in vivo activities and mechanistic characterization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

A high-throughput screening assay for small molecules that disrupt yeast cell integrity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Current challenges in the management of invasive fungal infections

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Teaching old drugs new tricks: reincarnating immunosuppressants as antifungal drugs.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Observation and significance of growth inhibition of Saccharomyces cerevisiae (A224A) by the anti-oestrogen drug tamoxifen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

Tackling Human Fungal Infections

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435257

10.1371/JOURNAL.PPAT.1002870

27 November 2018

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22969422%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22969422%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

22969422

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22969422%20AND%20SRC:MED&resulttype=core&format=json