Integrating cellular metabolism into a multiscale whole-body model (Q28484829)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133351%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Integrating cellular metabolism into a multiscale whole-body model (English)

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17 February 2020

2

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17 February 2020

Rolf Findeisen

4

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17 February 2020

Jörg Lippert

5

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17 February 2020

Lars Kuepfer

6

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17 February 2020

author name string

Markus Krauss

1

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17 February 2020

Steffen Borchers

3

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17 February 2020

language of work or name

English

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publication date

25 October 2012

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PLOS Computational Biology

17 February 2020

published in

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17 February 2020

volume

8

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17 February 2020

issue

10

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17 February 2020

page(s)

e1002750

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Creative Commons Attribution 4.0 International

17 February 2020

copyright license

start time

25 October 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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Dynamic analysis of integrated signaling, metabolic, and regulatory networks

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Physiologically Based Pharmacokinetic Modeling: Principles and Applications

29 September 2017

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Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention

29 September 2017

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A computational systems biology software platform for multiscale modeling and simulation: integrating whole-body physiology, disease biology, and molecular reaction networks.

29 September 2017

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Towards whole-body systems physiology.

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Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism

2 June 2018

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Physiologically based pharmacokinetic modeling 1: predicting the tissue distribution of moderate-to-strong bases.

2 June 2018

1 reference

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Severity of hyperammonemic encephalopathy correlates with brain ammonia level and saturation of glutamine synthetase in vivo.

2 June 2018

1 reference

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High-throughput classification of yeast mutants for functional genomics using metabolic footprinting.

2 June 2018

1 reference

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Physiologically based pharmacokinetic modelling 2: predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions.

21 January 2018

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A physiologic model for simulating gastrointestinal flow and drug absorption in rats.

21 January 2018

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Risk to the breast-fed neonate from codeine treatment to the mother: a quantitative mechanistic modeling study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002750

Integrating metabolic, transcriptional regulatory and signal transduction models in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002750

Xanthine oxidase inhibition by allopurinol affects the reliability of urinary caffeine metabolic ratios as markers for N -acetyltransferase 2 and CYP1A2 activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002750

Correlation between ammonia levels and the severity of hepatic encephalopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002750

Persistent arterial hyperammonemia increases the concentration of glutamine and alanine in the brain and correlates with intracranial pressure in patients with fulminant hepatic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002750

Development of a physiology-based whole-body population model for assessing the influence of individual variability on the pharmacokinetics of drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002750

Mechanism-based prediction of particle size-dependent dissolution and absorption: cilostazol pharmacokinetics in dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002750

Analysis of structural robustness of metabolic networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002750

Monte Carlo sampling can be used to determine the size and shape of the steady-state flux space.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1002750

Pharmacogenomics of codeine, morphine, and morphine-6-glucuronide: model-based analysis of the influence of CYP2D6 activity, UGT2B7 activity, renal impairment, and CYP3A4 inhibition.

21 January 2018

1 reference

12 December 2020

1 reference

12 December 2020

Physiology-based pharmacokinetic modeling: ready to be used

1 reference

12 December 2020

Network-based prediction of human tissue-specific metabolism

1 reference

12 December 2020

Plasma glutamine concentration: A guide in the management of urea cycle disorders

1 reference

12 December 2020

Ammonia metabolism during exercise in man

1 reference

12 December 2020

10.1371/JOURNAL.PCBI.1002750

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133351%20AND%20SRC:MED&resulttype=core&format=json

journals/ploscb/KraussSBFLK12

17 February 2020

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133351%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133351%20AND%20SRC:MED&resulttype=core&format=json