Stabilization of the tertiary structure of the cholera toxin A1 subunit inhibits toxin dislocation and cellular intoxication (Q28485727)

24 January 2017

title

Stabilization of the tertiary structure of the cholera toxin A1 subunit inhibits toxin dislocation and cellular intoxication (English)

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24 January 2017

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2

Tuhina Banerjee

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24 January 2017

Shane Massey

1

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24 January 2017

Abhay H. Pande

3

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24 January 2017

Michael Taylor

4

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24 January 2017

Suren A. Tatulian

5

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24 January 2017

Ken Teter

6

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24 January 2017

language of work or name

English

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publication date

13 November 2009

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Journal of Molecular Biology

24 January 2017

published in

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24 January 2017

volume

393

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24 January 2017

issue

5

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24 January 2017

page(s)

1083–1096

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Ricin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37 {degrees}C

24 January 2017

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One step at a time: endoplasmic reticulum-associated degradation

19 March 2017

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The pertussis toxin S1 subunit is a thermally unstable protein susceptible to degradation by the 20S proteasome

19 March 2017

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Cholera toxin: a paradigm for multi-functional engagement of cellular mechanisms (Review)

19 March 2017

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19 March 2017

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Novel cell-based method to detect Shiga toxin 2 from Escherichia coli O157:H7 and inhibitors of toxin activity

19 March 2017

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Cholera toxin structure, gene regulation and pathophysiological and immunological aspects

29 September 2017

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Order-disorder-order transitions mediate the activation of cholera toxin.

29 September 2017

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Cholera toxin up-regulates endoplasmic reticulum proteins that correlate with sensitivity to the toxin

29 September 2017

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Derlin-1 facilitates the retro-translocation of cholera toxin

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Protein disulfide isomerase-like proteins play opposing roles during retrotranslocation

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The cholera toxin A1(3) subdomain is essential for interaction with ADP-ribosylation factor 6 and full toxic activity but is not required for translocation from the endoplasmic reticulum to the cytosol

29 September 2017

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29 September 2017

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The intracellular voyage of cholera toxin: going retro.

29 September 2017

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Role of ubiquitination in retro-translocation of cholera toxin and escape of cytosolic degradation

29 September 2017

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Inhibition of endoplasmic reticulum-associated degradation in CHO cells resistant to cholera toxin, Pseudomonas aeruginosa exotoxin A, and ricin

29 September 2017

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Transfer of the cholera toxin A1 polypeptide from the endoplasmic reticulum to the cytosol is a rapid process facilitated by the endoplasmic reticulum-associated degradation pathway

29 September 2017

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29 September 2017

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Chemical chaperones mediate increased secretion of mutant alpha 1-antitrypsin (alpha 1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in alpha 1-AT deficiency

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Protein-disulfide isomerase-mediated reduction of the A subunit of cholera toxin in a human intestinal cell line.

29 September 2017

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Entry of cholera toxin into polarized human intestinal epithelial cells. Identification of an early brefeldin A sensitive event required for A1-peptide generation

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Internalization and degradation of cholera toxin by cultured cells: relationship to toxin action

29 September 2017

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Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway

29 September 2017

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Structure, stability, and receptor interaction of cholera toxin as studied by Fourier-transform infrared spectroscopy

29 September 2017

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Conformational instability of the cholera toxin A1 polypeptide

29 September 2017

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Cholera toxin is exported from microsomes by the Sec61p complex

2 June 2018

1 reference

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Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells

2 June 2018

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Brefeldin A blocks the response of cultured cells to cholera toxin. Implications for intracellular trafficking in toxin action.

2 June 2018

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BiP‐dependent export of cholera toxin from endoplasmic reticulum‐derived microsomes

2 June 2018

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27 November 2018

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A class of mutant CHO cells resistant to cholera toxin rapidly degrades the catalytic polypeptide of cholera toxin and exhibits increased endoplasmic reticulum-associated degradation.

27 November 2018

1 reference

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27 November 2018

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27 November 2018

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Effects of temperature on ADP-ribosylation factor stimulation of cholera toxin activity

27 November 2018

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Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus

27 November 2018

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Protein Disulfide Isomerase Acts as a Redox-Dependent Chaperone to Unfold Cholera Toxin

27 November 2018

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12 December 2020

Thermal stability and intersubunit interactions of cholera toxin in solution and in association with its cell-surface receptor ganglioside GM1

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12 December 2020

ELISA-type titertray assay of IgM anti-GM1 autoantibodies

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12 December 2020

Reduction of protein disulfide bonds in an oxidizing environment. The disulfide bridge of cholera toxin A-subunit is reduced in the endoplasmic reticulum

1 reference

12 December 2020

10.1016/J.JMB.2009.09.013

Identifiers

DOI

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PMC publication ID

2782630

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1 reference